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Specialty: Neurology
Source: Frontiers in Neurology

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Total 2557 results found since Jan 2013.

Predictive value of the Oxford Acute Severity of Illness Score in acute stroke patients with stroke-associated pneumonia
ConclusionOASIS can effectively predict the onset and death of SAP patients and provides a potential reference index for early diagnosis and the prediction of prognosis in patients with SAP. Our findings should be considered in clinical practice.
Source: Frontiers in Neurology - September 4, 2023 Category: Neurology Source Type: research

Secondary neurodegeneration following Stroke: what can blood biomarkers tell us?
Stroke is one of the leading causes of death and the primary source of disability in adults, resulting in neuronal necrosis of ischemic areas, and in possible secondary degeneration of regions surrounding or distant to the initial damaged area. Secondary neurodegeneration (SNDG) following stroke has been shown to have different pathogenetic origins including inflammation, neurovascular response and cytotoxicity, but can be associated also to regenerative processes. Aside from focal neuronal loss, ipsilateral and contralateral effects distal to the lesion site, disruptions of global functional connectivity and a transcallos...
Source: Frontiers in Neurology - September 1, 2023 Category: Neurology Source Type: research

Strengthening stroke prevention and awareness in the Philippines: a conceptual framework
This article focuses on stroke prevention and awareness in the Philippines, a country grappling with high stroke incidence and limited healthcare resources. The two-pronged approach presented by the authors aims to address the challenges of stroke care by combining community-based prevention and targeted public awareness campaigns. The community-based stroke prevention component involves personalized risk factor assessments and tailored interventions conducted at local health centers. By identifying modifiable risk factors such as hypertension, diabetes, smoking, and elevated cholesterol levels, healthcare professionals ca...
Source: Frontiers in Neurology - August 31, 2023 Category: Neurology Source Type: research

Prediction models for post-thrombectomy brain edema in patients with acute ischemic stroke: a systematic review and meta-analysis
ConclusionDespite the promising discriminative ability shown by studies on prediction models for post-thrombectomy brain edema in AIS patients, concerns related to a high risk of bias and limited external validation remain. Future research should prioritize the external validation and optimization of these models. There is an urgent need for large-scale, multicenter studies to develop robust, user-friendly models for real-world clinical application.Systematic review registrationhttps://www.crd.york.ac.uk, unique Identifier: CRD42022382790.
Source: Frontiers in Neurology - August 31, 2023 Category: Neurology Source Type: research

Comparison of three measures for insomnia in ischemic stroke patients: Pittsburgh sleep quality index, insomnia severity index, and Athens insomnia scale
ConclusionEach of the three questionnaires has advantages and disadvantages when assessing insomnia. In the evaluation of insomnia in IS patients, the best questionnaire selection should be made according to the purpose of clinical evaluation and considering the sensitivity and specificity.
Source: Frontiers in Neurology - August 30, 2023 Category: Neurology Source Type: research

Risk factors and a prediction model for unruptured intracranial aneurysms in patients with ischemic stroke using carotid intima-media thickness and systemic atherosclerosis
ConclusionThe findings revealed that the risk factors for UIA in patients with IS included aspirin use, elevated CRP level, and smaller carotid IMT, and the predictive value of the prediction model was relatively better.
Source: Frontiers in Neurology - August 29, 2023 Category: Neurology Source Type: research

Investigation of the efficacy of low-frequency repetitive transcranial magnetic stimulation on upper-limb motor recovery in subacute ischemic stroke without cortical involvement: a protocol paper for a multi-center, double-blind randomized controlled trial
ConclusionThis study will provide evidence on the efficacy of low-frequency rTMS in motor function recovery of the upper limb in patients with subacute, subcortical, and brainstem ischemic stroke.Clinical trial registrationClinicalTrials.gov, identifier [NCT05535504].
Source: Frontiers in Neurology - August 25, 2023 Category: Neurology Source Type: research

Quantitative assessment of collateral time on perfusion computed tomography in acute ischemic stroke patients
ConclusionOur results indicate that perfusion computed tomography can accurately quantify the collateral time after acute ischemic stroke.
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research

A patient with MELAS syndrome combined with autoimmune abnormalities: a case report
ConclusionMitochondrial encephalomyopathy is a rare clinical condition; however, the association with autoimmune diseases is not yet clear and still needs further research and analysis.
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research

Translation of obstructive sleep apnea pathophysiology and phenotypes to personalized treatment: a narrative review
Obstructive Sleep Apnea (OSA) arises due to periodic blockage of the upper airway (UA) during sleep, as negative pressure generated during inspiration overcomes the force exerted by the UA dilator muscles to maintain patency. This imbalance is primarily seen in individuals with a narrowed UA, attributable to factors such as inherent craniofacial anatomy, neck fat accumulation, and rostral fluid shifts in the supine posture. Sleep-induced attenuation of UA dilating muscle responsiveness, respiratory instability, and high loop gain further exacerbate UA obstruction. The widespread comorbidity profile of OSA, encompassing car...
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research

Editorial: Understanding PFO-associated stroke
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research

Kinematic analysis of movement patterns during a reach-and-grasp task in stroke patients
ConclusionPost-stroke patients have unique spatiotemporal and kinematic movement patterns during a reach-and grasp-task according to the impairment severity.
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research

Editorial: Machine learning in data analysis for stroke/endovascular therapy
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research

Botulinum toxin use in patients with post-stroke spasticity: a nationwide retrospective study from France
ConclusionOur analysis of the exhaustive PMSI database showed a suboptimal implementation of BoNT-A treatment recommendations in France. BoNT-A treatment initiation and re-administration are low, particularly in patients with post-stroke spasticity. Further investigations may help explain this observation, and may target specific actions to improve spasticity-related care pathway.
Source: Frontiers in Neurology - August 23, 2023 Category: Neurology Source Type: research

Addressing mood and fatigue in return-to-work programmes after stroke: a systematic review
ConclusionOverall, the findings demonstrated that mood and fatigue are poorly addressed in rehabilitation programmes aimed at improving return-to-work after stroke, despite being a significant predictor of return-to-work. There is limited and inconsistent use of mood and fatigue screening tools. The findings were generally able to provide guidance and recommendations in the development of a stroke rehabilitation programme for return-to-work, highlighting the need to include components addressing and measuring psychological support and fatigue management.
Source: Frontiers in Neurology - August 22, 2023 Category: Neurology Source Type: research