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Specialty: Neurology
Source: Frontiers in Neurology

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Total 2557 results found since Jan 2013.

Establishing a pediatric acute stroke protocol: experience of a new pediatric stroke program and predictors of acute stroke
ConclusionA trainee developed and initiated pediatric acute stroke protocol quickly implemented a hospital wide change in management that led to rapid diagnosis and triage of pediatric stroke and suspected stroke. No additional personnel or resources were needed for this change, and we encourage other hospitals and emergency departments to implement similar systems. Additionally, hemiparesis and altered mental status were predictors of stroke for pediatric acute stroke activation in our Bayesian statistical analysis. However credible intervals were wide due to the small sample size. Further multicenter data collection coul...
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research

Causal relationship between ischemic stroke and its subtypes and frozen shoulder: a two-sample Mendelian randomization analysis
ConclusionsOur study confirmed the causal relationship between any IS level and increased risk of FS. Furthermore, the same results were obtained in the replication stage with lacunar stroke as an exposure factor. However, there was no direct causal relationship between the subtypes of IS and FS. Our study provides theoretical support for shoulder care for patients with IS.
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research

Associations of lesion location, structural disconnection, and functional diaschisis with depressive symptoms post stroke
DiscussionBased on our results, and other recent lesion studies, we see growing evidence for a prominent role of right frontostriatal brain circuits in PSDS.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

The effect of telerehabilitation on balance in stroke patients: is it more effective than the traditional rehabilitation model? A meta-analysis of randomized controlled trials published during the COVID-19 pandemic
ConclusionStudies on changes in medical conditions during the COVID-19 pandemic also demonstrated that, for stroke patients, telerehabilitation achieves similar effects as the conventional rehabilitation model and can act as a continuation of the conventional rehabilitation model. Owing to the different equipment and intervention programs of telerehabilitation, its curative effect on the static balance and reactive balance of stroke patients may be different. Currently, telerehabilitation may be more conducive to the rehabilitation of patients' static balance abilities, while conventional rehabilitation is more effective f...
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

Determinants of cerebral collateral circulation in acute ischemic stroke due to large vessel occlusion
DiscussionThe results of our study suggest that risk factors and demographics do not influence the development of collateral circles, except for a negative relation with previous ischemic events. We confirm an already reported observation of a possible protective effect of collaterals on tissue damage assuming NIHSS as its surrogate. The association between left hemispheric stroke and better collaterals deserves to be further explored. Further efforts are needed to identify the factors that favor the development of collaterals.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

Effects of herpes zoster vaccination and antiviral treatment on the risk of stroke: a systematic review and meta-analysis
ConclusionsThis meta-analysis suggests that the HZV, but not antiviral treatment, decreases the odds of developing stroke.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

Transcriptomic analysis reveals the potential biological mechanism of AIS and lung adenocarcinoma
DiscussionOur findings suggest that the hub genes we found in this study contribute to the development and progression of AIS and LUAD by altering the cellular senescence pathway. Thus, they may be promising markers for diagnosis and prognosis.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

Capsular warning syndrome and its clinical awareness and therapeutic approach: two case reports and a systematic review of the literature
ConclusionOur cases fit with the description of patients with partial recovery and risk factors (hypertension, diabetes, and smoking) in male patients. There is a lack of evidence regarding the best treatment option; dual antiplatelet therapy and anticoagulation therapy are strong contenders for a favorable result.
Source: Frontiers in Neurology - May 16, 2023 Category: Neurology Source Type: research

Patent foramen ovale closure in non-elderly and elderly patients with cryptogenic stroke: a hospital-based cohort study
DiscussionPFO closure was associated with a reduced risk of the primary outcome in patients with PFO and CS in our total cohort, which included non-elderly and elderly patients. Compared to those without PFO closure, elderly patients with PFO closure had a better functional outcome at 180 days. PFO closure might be considered in selected elderly patients with PFO.
Source: Frontiers in Neurology - May 16, 2023 Category: Neurology Source Type: research

Women and stroke: disparities in clinical presentation, severity, and short- and long-term outcomes
ConclusionOlder age at presentation contributes to poor outcomes following acute stroke in women. Other contributing factors include delays in admission to the hospital, lower rates of thrombolysis, and lower rates of provision of preventative treatments.
Source: Frontiers in Neurology - May 15, 2023 Category: Neurology Source Type: research

The role of homocysteine levels as a risk factor of ischemic stroke events: a systematic review and meta-analysis
ConclusionThis meta-analysis and systematic review indicate that ischemic stroke patients have significantly higher homocysteine levels than controls. Detecting hyperhomocysteinemia and reducing homocysteine levels should be explored among individuals at increased risk for ischemic stroke.
Source: Frontiers in Neurology - May 12, 2023 Category: Neurology Source Type: research

The efficacy of stereotactic minimally invasive thrombolysis at different catheter positions in the treatment of small- and medium-volume basal ganglia hemorrhage (SMITDCP I): a randomized, controlled, and blinded endpoint phase 1 trial
ConclusionStereotactic minimally invasive puncture combined with urokinase for the treatment of small- and medium-volume hemorrhage in the basal ganglia, including catheterization through the long axis of the hematoma, led to significantly better drainage effects and fewer complications. However, there was no significant difference in short-term NIHSS scores between the two types of catheterization.
Source: Frontiers in Neurology - May 12, 2023 Category: Neurology Source Type: research

CT-based thrombus radiomics nomogram for predicting secondary embolization during mechanical thrombectomy for large vessel occlusion
ConclusionThis nomogram could be used to optimize the surgical MT procedure for LVO based on the risk of developing SE.
Source: Frontiers in Neurology - May 12, 2023 Category: Neurology Source Type: research

Lasting impairments following transient ischemic attack and minor stroke: a systematic review protocol
IntroductionThe focus on medical management and secondary prevention following Transient Ischemic Attack (TIA) and minor stroke is well-established. Evidence is emerging that people with TIA and minor stroke can experience lasting impairments as fatigue, depression, anxiety, cognitive impairment, and communication difficulties. These impairments are often underrecognized and inconsistently treated. Research in this area is developing rapidly and an updated systematic review is required to evaluate new evidence as it emerges. This living systematic review aims to describe the prevalence of lasting impairments and how they a...
Source: Frontiers in Neurology - May 12, 2023 Category: Neurology Source Type: research

Effect of Tai Chi Yunshou training on the balance and motor functions of stroke patients: a systematic review and meta-analysis of randomized controlled trials
ConclusionInitial evidence seems to show that Tai Chi Yunshou training can improve the balance and motor function of stroke survivors and further improve walking ability and daily living ability, and the rehabilitation effect may be better than that of conventional rehabilitation training.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=376969, identifier [CRD42022376969].
Source: Frontiers in Neurology - May 12, 2023 Category: Neurology Source Type: research