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Risks of neurological and psychiatric sequelae 2 years after hospitalisation or intensive care admission with COVID-19 compared to admissions for other causes
Brain Behav Immun. 2023 May 30:S0889-1591(23)00132-0. doi: 10.1016/j.bbi.2023.05.014. Online ahead of print.ABSTRACTThe association between COVID-19 and subsequent neurological and psychiatric disorders is well established. However, two important questions remain unanswered. First, what are the risks in those admitted to intensive care unit (ICU) with COVID-19? Admission to ICU is itself associated with neurological and psychiatric sequelae and it is not clear whether COVID-19 further increases those risks or changes their profile. Second, what are the trajectories of neurological and psychiatric risks in patients admitted...
Source: Brain, Behavior, and Immunity - June 1, 2023 Category: Neurology Authors: Harriet Ley Zuzanna Skorniewska Paul J Harrison Maxime Taquet Source Type: research

Sex and age effects on risk of non-traumatic subarachnoid hemorrhage: Retrospective cohort study of 124,234 cases using electronic health records
This study describes the antecedent characteristics of SAH patients, compares the risk of SAH between women and men, and explores if this changes with age.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2023 Category: Neurology Authors: Charlotte H Harrison, Maxime Taquet, Paul J Harrison, Peter J Watkinson, Matthew J Rowland Source Type: research

Impact of emergency department arrival time on door-to-needle time in patients with acute stroke
ConclusionFactors that contribute most to a delay in DTN time include arrival during the night shift, lack of a dedicated stroke team, longer time-to-CT read, and arrival as a walk-in. All of these are addressable factors from an operational standpoint and should be considered when performing quality improvement of hospital protocols.
Source: Frontiers in Neurology - March 30, 2023 Category: Neurology Source Type: research

Opioid-Use, COVID-19 Infection, and Their Neurological Implications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an imminent threat to human health and public safety. ACE2 and transmembrane serine protease 2 proteins on host cells provide the viral entry point to SARS-CoV-2. Although SARS-CoV-2 mainly infects the respiratory system, there have been reports of viral neurotropism and central nervous system injury as indicated by plasma biomarkers, including neurofilament light chain protein and glial fibrillary acidic protein. Even with a small proportion of infections leading to neurological manifestation, the overall number remains high. Common neurological manifestation...
Source: Frontiers in Neurology - May 23, 2022 Category: Neurology Source Type: research

Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits
Conclusions and Relevance: The hazard of incident cardiovascular disease is higher in those receiving eiASMs. The association is dose dependent and the absolute difference in hazard seems to reach clinical significance by approximately 10 years from first exposure.PMID:35444497 | PMC:PMC8988723 | DOI:10.1177/15357597211070392
Source: Epilepsy Curr - April 21, 2022 Category: Neurology Authors: David G Vossler Source Type: research

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