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Treatment of In-stent Restenosis of the Internal Carotid Artery Using Drug-eluting Balloons
ConclusionThe use of DEB angioplasty is a  safe and effective treatment of ICA ISR lesions, yielding significantly better results compared to other modalities. Randomized multicenter studies are warranted.
Source: Clinical Neuroradiology - September 7, 2023 Category: Neurology Source Type: research

Impact of ongoing intravenous thrombolysis until completion of endovascular treatment in large vessel occlusion stroke patients
ConclusionOur findings suggest that ongoing IVT until ET completion has a favorable impact on both clinical and angiographic outcomes, as well as on periprocedural conditions, regardless of the overall time intervals involved. Therefore, rapid ET after IVT should be sought in order to take advantage of the additive effect of ongoing IVT during ET. Future studies should consider IVT timing in the context of ET as a potential confounder and treatment target.
Source: Frontiers in Neurology - August 4, 2023 Category: Neurology Source Type: research

Associations between structure- and process-orientated measures and stroke long term mortality – an observational study based on routine data
This study analyzes these measures in combination, considering patients ’ comorbidities as well as stroke severity in a longitudinal perspective.
Source: Journal of Stroke and Cerebrovascular Diseases - July 27, 2023 Category: Neurology Authors: Dijana Ebbeler, Michael Schneider, Otto Busse, Klaus Berger, Patrik Dr öge, Christian Günster, Björn Misselwitz, Nina Timmesfeld, Max Geraedts Source Type: research

Outcome after intracranial hemorrhage under dabigatran and reversal with idarucizumab versus under vitamin-K-antagonists – the RIC-ICH study
ConclusionThese results, based on data from routine clinical practice, suggest that in-hospital mortality after idarucizumab treatment is comparable to that in patients pretreated with VKA. Due to the low precision of estimates, the results must be interpreted with caution.
Source: Frontiers in Neurology - July 24, 2023 Category: Neurology Source Type: research

Clinical Course and Recurrence in Transient Global Amnesia: A Study From the TEMPiS Telestroke Network
CONCLUSIONS: Arterial hypertension is prevalent in TGA patients, with elevated blood pressure being the most-frequent concomitant condition. In our cohort, recurrence of TGA occurred in approximately one-fifth of patients. Concomitant conditions such as migraine, hypothyroidism, and atrial fibrillation occurred at different frequencies in the two groups.PMID:37455507 | DOI:10.3988/jcn.2022.0368
Source: Journal of Clinical Neurology - July 17, 2023 Category: Neurology Authors: Shadi Taheri Nils Peters Annaelle Zietz Berthold Abel Gordian Hubert Filip Barinka Hanni Wiestler Irena Kovacic Ralf Linker Felix Schlachetzki Roland Backhaus Source Type: research

Prospective collection of blood plasma samples to identify potential biomarkers for the prehospital stroke diagnosis (ProGrEss-Bio): study protocol for a multicenter prospective observational study
This study will evaluate whether a single blood biomarker or a combination of biomarkers can distinguish patients with AIS and ICH from patients with stroke and SM in the early phase after symptom onset in the prehospital setting. In addition, the kinetics of blood biomarkers in AIS and ICH patients will be investigated. Our goal is to evaluate new ways to reliably diagnose stroke in the prehospital setting and thus accelerate the application of evidence-based therapies to stroke patients.
Source: Frontiers in Neurology - July 6, 2023 Category: Neurology Source Type: research

Radiation Exposure in Interventional Stroke Treatment
ConclusionWe conducted a  retrospective study on radiation exposure during MT in Germany. Based on the results of more than 41,000 procedures, we observed that the DRL of 14,000 cGy·cm2 is currently appropriate but may be lowered over the next years. Furthermore, we identified several factors that contribute to high radiation exposure. This can aid in detecting the cause of an exceeded DRL and optimize the treatment workflow.
Source: Clinical Neuroradiology - June 6, 2023 Category: Neurology Source Type: research

Data lake-driven analytics identify nocturnal non-dipping of heart rate as predictor of unfavorable stroke outcome at discharge
ConclusionsOur data suggest that a lack of circadian HR modulation, specifically nocturnal non-dipping, is associated with short-term unfavorable functional outcome after stroke, and that including HR into machine learning-based prediction models may lead to improved stroke outcome prediction.
Source: Journal of Neurology - April 20, 2023 Category: Neurology Source Type: research

Patterns of acute ischemic stroke and intracranial hemorrhage in patients with COVID-19
In this study, we sought to investigate associations between neuroimaging findings with clinical, demographic, blood and cerebrospinal fluid (CSF) parameters, pre-existing conditions and the severity of acute COVID-19.Materials and methodsRetrospective multicenter data retrieval from 10 university medical centers in Germany, Switzerland and Austria between February 2020 and September 2021. We included patients with COVID-19, acute neurological symptoms and cranial imaging. We collected demographics, neurological symptoms, COVID-19 severity, results of cranial imaging, blood and CSF parameters during the hospital stay.Resul...
Source: Journal of Neurology - February 23, 2023 Category: Neurology Source Type: research

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