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Oral probiotic therapy improves motor function in a rodent model of sensorimotor stroke
In this study, we examined the effect of post-stroke oral probiotic therapy on motor behavior in the pre-clinical mouse endothelin-1 (ET-1) model of sensorimotor stroke. We found that post-stroke oral probiotic therapy with Cerebiome® (Lallemand, Montreal, Canada), containing B. longum R0175 and L. helveticus R0052, improved functional recovery and changed the composition of the post-stroke gut microbiota. Interestingly, oral Cerebiome® administration did not result in alterations of lesion volume or the number of CD8+/Iba1+ cells in the injured tissue. Overall, these findings suggest that probiotic treatment following i...
Source: Brain Research - June 26, 2023 Category: Neurology Authors: E Daniele Y Nazer I Kortebi D Lozano Casasbuenas Y Fan M Trinh T A Tompkins M Faiz Source Type: research

Supporting stroke survivors to meet their personal rehabilitation needs in community-based arm rehabilitation: development of initial programme theories to explore what may work for whom, how and under what circumstances
ConclusionThis realist-informed study enabled the development of initial programme theories to explain how and in what circumstances the augmented arm rehabilitation intervention may have enabled participants to meet their personal rehabilitation needs. Encouraging participants’ sense of intrinsic motivation and building therapeutic relationships appeared instrumental. These initial programme theories require further testing, refinement, and integration with the wider literature.
Source: Frontiers in Neurology - June 2, 2023 Category: Neurology Source Type: research

A qualitative pilot study exploring clients' and health-care professionals' experiences with aquatic therapy post-stroke in Ontario, Canada
CONCLUSIONS: Health-care professionals and clients reported numerous benefits of aquatic therapy post-stroke including, but not limited to, improvements in mobility, balance, wellbeing, and socialization. Lack of formal and informal education and communication as participants' transition from rehab to community were viewed as barriers to aquatic therapy use post-stroke. Developing education material and communication strategies may improve the uptake of aquatic therapy post-stroke.PMID:36999561 | DOI:10.1080/10749357.2023.2195590
Source: Topics in Stroke Rehabilitation - March 31, 2023 Category: Neurology Authors: Andresa R Marinho-Buzelli Abirami Vijayakumar Elizabeth Linkewich Catherine Gareau Hasnain Mawji Zoe Li Sander L Hitzig Source Type: research

Advance Consent in Acute Stroke Trials: Survey of Canadian Stroke Physicians
Can J Neurol Sci. 2023 Feb 17:1-4. doi: 10.1017/cjn.2023.12. Online ahead of print.ABSTRACTAdvance consent presents a potential solution to the challenge of obtaining informed consent for participation in acute stroke trials. Clinicians in stroke prevention clinics are uniquely positioned to identify and seek consent from potential stroke trial participants. To assess the acceptability of advance consent to Canadian stroke clinic physicians, we performed an online survey. We obtained 58 respondents (response rate 35%): the vast majority (82%) expressed comfort with obtaining advance consent and 92% felt that doing so would...
Source: The Canadian Journal of Neurological Sciences - February 17, 2023 Category: Neurology Authors: Ubong Udoh Brian Dewar Stuart Nicholls Mark Fedyk Robert Fahed Jeff Perry Michael D Hill Bijoy Menon Richard H Swartz Alexandre Y Poppe Sophia Gocan Jamie Brehaut Katie Dainty Victoria Shepherd Dar Dowlatshahi Michel Shamy Source Type: research

Mediation of post-stroke function by cognition in the Canadian Longitudinal Study on Aging
Can J Neurol Sci. 2023 Jan 11:1-29. doi: 10.1017/cjn.2023.6. Online ahead of print.NO ABSTRACTPMID:36627236 | DOI:10.1017/cjn.2023.6
Source: The Canadian Journal of Neurological Sciences - January 10, 2023 Category: Neurology Authors: Raed A Joundi Megan E O'Connell Scott Patten Eric E Smith Source Type: research

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