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Stroke and the risk of gastrointestinal disorders: A Mendelian randomization study
ConclusionThis study provides proof of the presence of a brain–gut axis. Among the complications of ICH, PUD and GERD were more common and associated with the site of hemorrhage.
Source: Frontiers in Neurology - February 21, 2023 Category: Neurology Source Type: research

Canadian Stroke Best Practice Recommendations: Acute Stroke Management, 7 < sup > th < /sup > Edition Practice Guidelines Update, 2022
Can J Neurol Sci. 2022 Dec 19:1-94. doi: 10.1017/cjn.2022.344. Online ahead of print.NO ABSTRACTPMID:36529857 | DOI:10.1017/cjn.2022.344
Source: The Canadian Journal of Neurological Sciences - December 18, 2022 Category: Neurology Authors: Manraj Heran Patrice Lindsay Gord Gubitz Amy Yu Aravind Ganesh Rebecca Lund Sacha Arsenault Doug Bickford Donnita Derbyshire Shannon Doucette Esseddeeg Ghrooda Devin Harris Nick Kanya-Forstner Eric Kaplovitch Zachary Liederman Shauna Martiniuk Marie McCle Source Type: research

Mortality after total anterior circulation stroke: a 25-year observational study
Can J Neurol Sci. 2022 Jun 20:1-28. doi: 10.1017/cjn.2022.262. Online ahead of print.NO ABSTRACTPMID:35722755 | DOI:10.1017/cjn.2022.262
Source: The Canadian Journal of Neurological Sciences - June 20, 2022 Category: Neurology Authors: J Oliver Neal Sherry Hu John Reid Kara Matheson Gord Gubitz Wendy Simpkin Christine Christian Stephen Phillips Source Type: research

Patients with Cerebral Stroke Have an Increased Risk of Gastroesophageal Reflux Disease: A Population-Based Cohort Study
This study was designed to investigate the prevalence and risk of gastroesophageal reflux disease (GERD) between patients with stroke and those without stroke in Taiwan.
Source: Journal of Stroke and Cerebrovascular Diseases - January 8, 2018 Category: Neurology Authors: Chen-Shu Chang, Hsuan-Ju Chen, Chun-Hui Liao Source Type: research

Proton Pump Inhibitors and Dementia Incidence
To the Editor I read with interest the article by Gomm et al investigating the association of proton pump inhibitors and dementia. The authors are to be commended for their large data set, analysis, and detailed proposed pathophysiologic mechanism by which this association might occur. However, 2 important medical comorbidities seem to be missing from their study: gastroesophageal reflux disease and obstructive sleep apnea. Both of these comorbidities can cause cognitive issues, especially in those with apolipoprotein E genetic variants and those who have had a stroke. Gastroesophageal reflux disease would constitute the r...
Source: JAMA Neurology - June 20, 2016 Category: Neurology Source Type: research

Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue Following Stroke practice guidelines, update 2015
Every year, approximately 62 000 people with stroke and transient ischemic attack are treated in Canadian hospitals, and the evidence suggests one‐third or more will experience vascular‐cognitive impairment, and/or intractable fatigue, either alone or in combination. The 2015 update of the Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue Module guideline is a comprehensive summary of current evidence‐based recommendations for clinicians in a range of settings, who provide care to patients following stroke. The three consequences of stroke that are the focus of the this guideline (poststrok...
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Gail A. Eskes, Krista L. Lanctôt, Nathan Herrmann, Patrice Lindsay, Mark Bayley, Laurie Bouvier, Deirdre Dawson, Sandra Egi, Elizabeth Gilchrist, Theresa Green, Gord Gubitz, Michael D. Hill, Tammy Hopper, Aisha Khan, Andrea King, Adam Kirton, Paige Moorh Tags: Guidelines Source Type: research

Striving for excellence: stroke guidelines are a crucial foundation
Source: International Journal of Stroke - March 16, 2015 Category: Neurology Authors: Mark Bayley, Stephen Phillips, M. Patrice Lindsay, Gord Gubitz, Eric E. Smith, Robert Côtê, Michael D. Hill Tags: Editorial Source Type: research

Differences in wake‐up and unknown onset stroke examined in a stroke registry
ConclusionWUS has lower rates of ICH but similar stroke severity and outcomes to AOS. UOS prevalence appears to be increasing, with higher stroke severity and worse prognosis.
Source: International Journal of Stroke - October 1, 2014 Category: Neurology Authors: John M. Reid, Dingwei Dai, Bharath Cheripelli, Christine Christian, Yvette Reidy, Gord J. Gubitz, Stephen J. Phillips Tags: Research Source Type: research

Gastroesophageal Reflux during Enteral Feeding in Stroke Patients: A 24-hour Esophageal pH-monitoring Study
Conclusions: GER is associated with aspiration pneumonia and occurs more often in patients with stroke lesions in the left hemisphere.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2011 Category: Neurology Authors: Yukie Satou, Hiroaki Oguro, Yo Murakami, Keiichi Onoda, Shingo Mitaki, Chizuko Hamada, Ryo Mizuhara, Shuhei Yamaguchi Tags: Original Articles Source Type: research