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Specialty: Laboratory Medicine

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Total 458 results found since Jan 2013.

Hemophagocytic lymphohistiocytosis diagnosed by bone marrow trephine biopsy in living post-COVID-19 patients: case report and mini-review
AbstractHemophagocytic lymphohistiocytosis (HLH) constitutes a life-threatening inflammatory syndrome. Postmortem histological findings of bone marrow (BM) from COVID-19 patients showed histiocytosis and hemophagocytosis and supported the hypothesis that secondary HLH (sHLH) may be triggered by SARS-CoV-2 infection. However, there are a limited number of sHLH cases in which trephine has been performed in living post-COVID-19 patients. Here we present a recent case and a mini-review of sHLH diagnosed by trephine biopsy in living patients after COVID-19. An 81-year-old man with a past medical history of hypertension, diabete...
Source: Journal of Molecular Histology - June 14, 2022 Category: Laboratory Medicine Source Type: research

Muscle Energy Technique plus Neurac Method in Stroke Patients with Hemiplegia Complicated by Diabetes Mellitus and Assessment of Quality of Life
CONCLUSION: Neurac method plus MET improves the independent mobility of stroke patients with hemiplegia and diabetes, relieves pain, enhances balance and stability, mitigates limb dysfunction, and boosts patients' quality of life, so it is worthy of clinical application.PMID:35585937 | PMC:PMC9110136 | DOI:10.1155/2022/6318721
Source: Disease Markers - May 19, 2022 Category: Laboratory Medicine Authors: Jingyan Wang Shuang Wang Hongmei Wu Shuxin Dong Baojun Zhang Source Type: research

The Association of Serum Neurofilament Light Chain and Acute Ischaemic Stroke Is Influenced by Effective Revascularization
CONCLUSION: sNfL levels at admission could be a potential biomarker for predicting clinical deficits and prognosis in the natural course of AIS.PMID:35557872 | PMC:PMC9090527 | DOI:10.1155/2022/5236080
Source: Disease Markers - May 13, 2022 Category: Laboratory Medicine Authors: Fa-Ying Zhou Dong-Wan Chen Hui-Yun Li Chi Zhu Ying-Ying Shen Ze-Yan Peng Ling Li Xian-Le Bu Gui-Hua Zeng Meng Zhang Yan-Jiang Wang Wang-Sheng Jin Source Type: research

Reducing Laboratory Turnaround Time in Patients With Acute Stroke and the Lack of Impact on Time to Reperfusion Therapy
CONCLUSIONS.—: The new laboratory workflow significantly decreased transportation time, TAT of individual tests, and the blood drawn-to-laboratory reported time. However, the time to treatment of acute ischemic stroke patients was not different between preimplementation and postimplementation.PMID:35486488 | DOI:10.5858/arpa.2021-0444-OA
Source: Archives of Pathology and Laboratory Medicine - April 29, 2022 Category: Laboratory Medicine Authors: Sasipong Trongnit Kanit Reesukumal Gerald J Kost Yongchai Nilanont Busadee Pratumvinit Source Type: research

Construction of a Joint Prediction Model for the Occurrence of Ischemic Stroke and Acute Myocardial Infarction Based on Bioinformatic Analysis
Dis Markers. 2022 Apr 4;2022:5967131. doi: 10.1155/2022/5967131. eCollection 2022.ABSTRACTIschemic stroke (IS) has imposed significant threat to both middle-aged and elderly people worldwide. Acute myocardial infarction (AMI) is a rare but serious complication following IS, which can further increase patient disability and mortality rates. With the development of intravenous thrombolysis and endovascular treatment, the prognosis of IS has been greatly improved. However, the pathogenesis of IS complicated with AMI is still unclear. To fill this gap, this work uses bioinformatic analysis, where IS and AMI datasets were combi...
Source: Disease Markers - April 14, 2022 Category: Laboratory Medicine Authors: Zhaolei Ma Lan Chu Chun-Feng Liu Wupeng Liu Jing Wei Source Type: research

Infarction Patterns and Recurrent Adverse Cerebrovascular Events in Moyamoya Disease
Dis Markers. 2022 Mar 29;2022:8255018. doi: 10.1155/2022/8255018. eCollection 2022.ABSTRACTFor moyamoya disease (MMD) patients who suffered an acute ischemic attack, the infarction patterns on DWI and its association with recurrent adverse cerebrovascular events (ACEs) after bypass surgery remain unknown. 327 patients who suffered an acute ischemic attack and received following revascularization surgery were retrospectively reviewed and were divided into three patterns according to the lesion number and distribution on DWI that obtained within 7 days of onset: no acute infarction (NAI), single acute infarction (SAI), and m...
Source: Disease Markers - April 8, 2022 Category: Laboratory Medicine Authors: Shao-Chen Yu Zi-Han Yin Chao-Fan Zeng Fa Lin Long Ma Yan Zhang Dong Zhang Ji-Zong Zhao Source Type: research

Circulating ADAMTS13 Levels Are Associated with an Increased Occurrence of Obstructive Sleep Apnea
CONCLUSION: Circulating ADAMTS13 levels were significantly correlated with the presence of OSA. ADAMTS13 may therefore function as a novel biomarker for monitoring the development and progression of OSA.PMID:35392493 | PMC:PMC8983172 | DOI:10.1155/2022/1504137
Source: Disease Markers - April 8, 2022 Category: Laboratory Medicine Authors: Mengling Huang Sheng Liu Shuang Liu Wanwan Wen Yu Ning Yifan Jia Yunxiao Yang Xiaolu Jiao Weiping Zheng Ming Zhang Source Type: research

Infarction Patterns and Recurrent Adverse Cerebrovascular Events in Moyamoya Disease
Dis Markers. 2022 Mar 29;2022:8255018. doi: 10.1155/2022/8255018. eCollection 2022.ABSTRACTFor moyamoya disease (MMD) patients who suffered an acute ischemic attack, the infarction patterns on DWI and its association with recurrent adverse cerebrovascular events (ACEs) after bypass surgery remain unknown. 327 patients who suffered an acute ischemic attack and received following revascularization surgery were retrospectively reviewed and were divided into three patterns according to the lesion number and distribution on DWI that obtained within 7 days of onset: no acute infarction (NAI), single acute infarction (SAI), and m...
Source: Disease Markers - April 8, 2022 Category: Laboratory Medicine Authors: Shao-Chen Yu Zi-Han Yin Chao-Fan Zeng Fa Lin Long Ma Yan Zhang Dong Zhang Ji-Zong Zhao Source Type: research

Circulating ADAMTS13 Levels Are Associated with an Increased Occurrence of Obstructive Sleep Apnea
CONCLUSION: Circulating ADAMTS13 levels were significantly correlated with the presence of OSA. ADAMTS13 may therefore function as a novel biomarker for monitoring the development and progression of OSA.PMID:35392493 | PMC:PMC8983172 | DOI:10.1155/2022/1504137
Source: Disease Markers - April 8, 2022 Category: Laboratory Medicine Authors: Mengling Huang Sheng Liu Shuang Liu Wanwan Wen Yu Ning Yifan Jia Yunxiao Yang Xiaolu Jiao Weiping Zheng Ming Zhang Source Type: research