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Specialty: Laboratory Medicine
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Total 458 results found since Jan 2013.
Efficacy of Butylphthalide in Combination with Edaravone in the Treatment of Acute Ischemic Stroke and the Effect on Serum Inflammatory Factors
CONCLUSION: The treatment of acute ischemic stroke with butylphthalide combined with edaravone has positive significance in improving blood circulation regulation and serum inflammatory factor levels and is reliable and worthy of clinical promotion.PMID:37082457 | PMC:PMC10113042 | DOI:10.1155/2023/9969437
Source: Disease Markers - April 11, 2023 Category: Laboratory Medicine Authors: Yan Li Zhen Hong Shaoquan Li Songwang Xie Junyong Wang Jian Wang Yongchang Liu Source Type: research
miR-9a-5p Protects Ischemic Stroke by Regulating Oxidative Stress and Mitochondrial Autophagy
CONCLUSION: miR-9a-5p protects against ischemic stroke by inhibiting OGD/R-induced mitochondrial autophagy and alleviating cellular oxidative stress injury.PMID:36845011 | PMC:PMC9957637 | DOI:10.1155/2023/5146305
Source: Disease Markers - February 27, 2023 Category: Laboratory Medicine Authors: Chunli Ma Qing Gao Li Zhang Geng Wu Chao Li Jun Chen Yuxuan Fu Lei Yang Source Type: research
Elabela-APJ axis mediates angiogenesis via YAP/TAZ pathway in cerebral ischemia/reperfusion injury
Transl Res. 2023 Feb 20:S1931-5244(23)00020-8. doi: 10.1016/j.trsl.2023.02.002. Online ahead of print.ABSTRACTAngiogenesis helps to improve neurological recovery by repairing damaged brain tissue and restoring cerebral blood flow (CBF). The role of the Elabela (ELA)-Apelin receptor (APJ) system in angiogenesis has gained much attention. We aimed to investigate the function of endothelial ELA on post-ischemic cerebral angiogenesis. Here, we demonstrated that the endothelial ELA expression was upregulated in the ischemic brain and treatment with ELA-32 mitigated brain injury and enhanced the restoration of CBF and newly form...
Source: Translational Research : the journal of laboratory and clinical medicine - February 22, 2023 Category: Laboratory Medicine Authors: Wenyu Li Pengfei Xu Lingqi Kong Shuo Feng Nan Shen Hongmei Huang Wuxuan Wang Xiang Xu Xinyue Wang Guoping Wang Yan Zhang Wen Sun Wei Hu Xinfeng Liu Source Type: research
CircFOXP1 alleviates brain injury after acute ischemic stroke by regulating STAT3/apoptotic signaling
Transl Res. 2023 Feb 12:S1931-5244(23)00022-1. doi: 10.1016/j.trsl.2023.01.007. Online ahead of print.ABSTRACTAccording to previous studies, circular RNAs (circRNAs) are involved in multiple pathological processes of acute ischemic stroke (AIS). However, the relationship between circFOXP1 and IS has not yet been reported. Here, we found that circFOXP1 expression was significantly decreased in the peripheral blood of AIS patients compared to controls and was associated with the severity and prognosis of AIS. Functionally, knockdown and overexpression of circFOXP1 promoted and inhibited apoptotic signaling, respectively, fol...
Source: Translational Research : the journal of laboratory and clinical medicine - February 14, 2023 Category: Laboratory Medicine Authors: Jialei Yang Wanting He Lian Gu Lulu Zhu Tian Liang Xueying Liang Qingqing Zhong Ruirui Zhang Aruo Nan Li Su Source Type: research
