Filtered By:
Specialty: Lipidology

This page shows you your search results in order of relevance. This is page number 7.

Order by Relevance | Date

Total 122 results found since Jan 2013.

Cytochrome P450 derived epoxidized fatty acids as a therapeutic tool against neuroinflammatory diseases
Publication date: April 2020Source: Prostaglandins & Other Lipid Mediators, Volume 147Author(s): Jogen Atone, Karen Wagner, Kenji Hashimoto, Bruce D. HammockAbstractCytochrome P450 (CYP) metabolism of arachidonic acid (ARA) produces epoxy fatty acids (EpFAs) such as epoxyeicosatrienoic acids (EETs) that are known to exert protective effects in inflammatory disorders. Endogenous EpFAs are further metabolized into corresponding diols by the soluble epoxide hydrolase (sEH). Through inhibition of sEH, many studies have demonstrated the cardioprotective and renoprotective effects of EpFAs; however, the role of sEH inhibition in...
Source: Prostaglandins and Other Lipid Mediators - December 6, 2019 Category: Lipidology Source Type: research

Associations between GUCY1A3 genetic polymorphisms and large artery atherosclerotic stroke risk in Chinese Han population: a case-control study
Previous genome-wide association studies have found two single nucleotide polymorphisms (SNP) rs7692387 and rs1842896 located on or near the GUCY1A3 gene were associated with coronary artery disease (CAD). GUCY1A...
Source: Lipids in Health and Disease - December 28, 2019 Category: Lipidology Authors: Jian-li Li, Liu-yu Liu, Dong-dong Jiang, Yi-ying Jiang, Guo-qiu Zhou, Dong-can Mo and Man Luo Tags: Research Source Type: research

Response to: “Arrhythmia paradox in patients with familial hypercholesterolemia”
We read the letter by Mirzaee and Cameron with great interest. We recently assessed the prognostic impact of clinically diagnosed familial hypercholesterolemia (FH) on long-term adverse cardiovascular outcomes in patients undergoing percutaneous coronary intervention for chronic and acute coronary syndromes. In our cohort, patients with probable or definite FH according to the Dutch Lipid Clinic Network faced a significant, approximate 2-fold increased risk for subsequent atherothrombotic events (death, myocardial infarction, or stroke) during a 6-year period of follow-up compared with patients with possible or unlikely FH.
Source: Journal of Clinical Lipidology - December 23, 2019 Category: Lipidology Authors: Maximilian Tscharre, Kurt Huber Tags: Letter to Editor Source Type: research

The LDL cholesterol in stroke limbo: how low can we go?
No abstract available
Source: Current Opinion in Lipidology - May 1, 2020 Category: Lipidology Tags: BIMONTHLY UPDATE: Edited by Alan Rees Source Type: research

Low-density Lipoprotein Cholesterol Levels Among Individuals Experiencing Statin-Associated Symptoms: Data from the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
Guidelines recommend adults who discontinue statin therapy due to statin-associated symptoms be re-initiated. Low-density lipoprotein cholesterol (LDL-C) levels achieved after statin re-initiation are unknown.
Source: Journal of Clinical Lipidology - June 16, 2020 Category: Lipidology Authors: Rikki M. Tanner, Lisandro D. Colantonio, Meredith L. Kilgore, Matthew T. Mefford, Dayl T. Chachappan, Katherine E. Mues, Monika M. Safford, Robert S. Rosenson, Paul Muntner Tags: Original Research Source Type: research

Lipoprotein(a) Levels and Association with Myocardial Infarction and Stroke in a Nationally Representative Cross-Sectional US Cohort
Lipoprotein(a) (Lp(a)) has not been well-studied in a nationally representative US cohort.
Source: Journal of Clinical Lipidology - July 2, 2020 Category: Lipidology Authors: Eric J. Brandt, Arya Mani, Erica S. Spatz, Nihar Desai, Khurram Nasir Tags: Original Research Source Type: research

Relationship between the non-HDLc-to-HDLc ratio and carotid plaques in a high stroke risk population: a cross-sectional study in China
This study...
Source: Lipids in Health and Disease - July 13, 2020 Category: Lipidology Authors: Yan Liu, Zhenwen Zhang, Binlan Xia, Liping Wang, Hengzhong Zhang, Yan Zhu, Chao Liu and Bin Song Tags: Research Source Type: research

Epigenetics of paraoxonases
Purpose of review Studies have shown the three-member paraoxonase (PON) multigene family to be involved in the development of a large variety of diseases with an inflammatory component. Environmental factors such as lifestyle-related factors differ widely between populations and it is important to consider that their impacts may be exerted through the epigenetic mechanisms, which connect genes, the environment and disease development and are a potential therapeutic avenue. Recent findings In the review period, very little was published on epigenetics of PON2 or PON3, mostly on their diagnostic value in cancer by measu...
Source: Current Opinion in Lipidology - July 30, 2020 Category: Lipidology Tags: HYPERLIPIDEMIA AND CARDIOVASCULAR DISEASE: Edited by Paul N. Durrington Source Type: research

Case Report: Acute Stroke Due to Cerebrovascular Atherosclerosis in Chinese-american Woman with Extremely High Level of High Density Lipoprotein-cholesterol (HDL-C) and Coronary Artery Calcium Score Equal Zero
Nothing to disclose.
Source: Journal of Clinical Lipidology - June 30, 2020 Category: Lipidology Authors: Jan Gong, Daniel Soffer Tags: Lipid Management in Special Populations Source Type: research

Case Report: 68 yo Chinese-American woman with high HDL-C and ischemic stroke attributed to intracranial atherosclerotic stenosis
Atherosclerotic cardiovascular disease (ASCVD) events are the most common cause of death in the United States and for most individuals who experience these events, may be predicted by risk identification tools. ASCVD risk calculators enable a clinician-patient discussion and the presence of risk-enhancing factors may further inform decision-making with respect to preventive pharmacotherapy, especially statin prescription. In cases where the decision of whether to treat with medicine is unclear, coronary artery calcium scoring by computed tomography offers enhanced risk stratification and may allow both clinicians and patie...
Source: Journal of Clinical Lipidology - January 27, 2021 Category: Lipidology Authors: Jan Gong, Stephanie Byers Asher, Brett Cucchiara, Marina Cuchel, Daniel Soffer Tags: Case Report Source Type: research

A cohort study on risk factors of high-density lipoprotein cholesterol hypolipidemia among urban Chinese adults
High-density lipoprotein cholesterol (HDL-C) hypolipidemia, a major type of dyslipidemia, has been associated with many kinds of diseases, such as stroke, coronary heart disease, obesity and diabetes, and has ...
Source: Lipids in Health and Disease - February 22, 2021 Category: Lipidology Authors: Fang Tang, Jian Wang, Stephen Nicholas, Dongfu Qian and Rugang Liu Tags: Research Source Type: research

Depression and cardiovascular disease
Purpose of review The purpose of this review is to outline the relationship between cardiovascular disease (CVD) and depression, both as a cause of and a result of CVD. Recent findings The prevalence of depression seems to be increasing in the general population. It is likely that depression will be even more of a problem for CVD patients in the post-COVID-19 pandemic era. New studies confirm the independent association of depression with later incident CVD, although perhaps not as strong as suggested by some previous studies. Depression seems to be becoming even more prevalent in CVD patients, with new...
Source: Current Opinion in Lipidology - April 30, 2021 Category: Lipidology Tags: LIPID METABOLISM Source Type: research

Triglyceride-lowering and Anti-inflammatory Mechanisms of Omega-3 Polyunsaturated Fatty Acids for Atherosclerotic Cardiovascular Risk Reduction
Atherosclerotic cardiovascular disease (ASCVD) is defined as acute coronary syndrome, stable angina, history of myocardial infarction, coronary or other arterial revascularization, ischemic stroke, transient ischemic attack, or peripheral arterial disease presumed to be of atherosclerotic origin.1 Despite continuous advances in medical intervention and surgical therapy for the treatment of ASCVD, the latter remains the leading cause of morbidity and mortality globally. In the United States, nearly 808,000 people died of ASCVD in 2014, translating to about 1 of every 3 deaths,2 and the death rate from ASCVD rose in 2015 by ...
Source: Journal of Clinical Lipidology - June 5, 2021 Category: Lipidology Authors: Qiyuan Keith Liu Tags: Review Article Source Type: research

Prostaglandin E2, 9S-, 13S-HODE and resolvin D1 are strongly associated with the post-stroke cognitive impairment
Publication date: Available online 10 June 2021Source: Prostaglandins & Other Lipid MediatorsAuthor(s): Dariusz Kotlęga, Barbara Peda, Arleta Drozd, Agnieszka Zembroń-Łacny, Ewa Stachowska, Jarosław Gramacki, Małgorzata Szczuko
Source: Prostaglandins and Other Lipid Mediators - June 12, 2021 Category: Lipidology Source Type: research

JCL Roundtable: Global Think Tank on Lipoprotein(a)
Lipoprotein(a) operates in causal pathways to promote atherosclerosis, arterial thrombosis, and aortic stenosis. It has been associated with rare cases of nonatherosclerotic arterial thrombotic stroke at any age. Inherited variation of lipoprotein(a) levels substantially increases cardiovascular risk in 20% of people worldwide. Recent progress in identifying the risk associated with lipoprotein(a) and in pursuing effective treatment has led to a recent Global Think Tank including representatives from the European Atherosclerosis Society, American Heart Association, Preventive Cardiovascular Nurses Association, National Lip...
Source: Journal of Clinical Lipidology - May 1, 2021 Category: Lipidology Authors: Lisa L. Maher, S. Lale Tokg özoğlu, Eduardo J. Sanchez, James A. Underberg, John R. Guyton Source Type: research