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Risk of Bleeding Complications With Different Peri-Operative Antithrombotic Regimens During Carotid Endarterectomy: a National Registry Analysis
Antithrombotic therapy is one of the cornerstones of the prevention of (recurrent) ocular or cerebral ischaemic events in patients with carotid artery stenosis. Randomised controlled trials on antithrombotic therapy for patients with minor ischaemic stroke and transient ischaemic attack (TIA) have recommended dual antiplatelet therapy (DAPT) in the three weeks following the index event. However, these trials excluded patients undergoing carotid revascularisation. To date, the optimal antithrombotic therapy during the peri-operative period of carotid endarterectomy (CEA) remains unclear.
Source: Journal of Vascular Surgery - January 19, 2023 Category: Surgery Authors: S.J.A. Donners, J.M. Mekke, E.S. van Hattum, R.J. Toorop, G.J. de Borst, Dutch Audit for Carotid Interventions (DACI) Collaborators Source Type: research

Management of extracranial carotid artery stenosis during endovascular treatment for acute ischaemic stroke: results from the MR CLEAN Registry
CONCLUSIONS: Functional outcomes were comparable after EVT with and without CAS. CAS during EVT might be a feasible option to treat the extracranial ICA stenosis but randomised studies are warranted to prove non-inferiority or superiority.PMID:36572506 | DOI:10.1136/svn-2022-001891
Source: Atherosclerosis - December 26, 2022 Category: Cardiology Authors: Sabine L Collette Michael P Rodgers Marianne A A van Walderveen Kars C J Compagne Paul J Nederkoorn Jeannette Hofmeijer Jasper M Martens Gert J de Borst Gert Jan R Luijckx Charles B L M Majoie Aad van der Lugt Reinoud P H Bokkers Maarten Uyttenboogaart MR Source Type: research

Risk of bleeding complications per different perioperative antithrombotic regimes during carotid endarterectomy: a national registry analysis
CONCLUSION: The effectiveness and safety of DAPT did not differ from single antiplatelet therapy (SAPT) in patients undergoing CEA and needs further evaluation in prospective studies. Considering additional data from the literature and guideline recommendations DAPT should be started immediately after stroke until 30 days after CEA followed by SAPT, due to possible reduction in the risk of recurrency.PMID:36031046 | DOI:10.1016/j.ejvs.2022.08.020
Source: PubMed: Eur J Vasc Endovasc ... - August 28, 2022 Category: Surgery Authors: Simone Ja Donners Joost M Mekke Eline S van Hattum Raechel J Toorop Gert J de Borst Dutch Audit for Carotid Interventions (DACI) Collaborators Source Type: research

Risk of Bleeding Complications With Different Peri-Operative Antithrombotic Regimens During Carotid Endarterectomy: a National Registry Analysis
Antithrombotic therapy is one of the cornerstones of the prevention of (recurrent) ocular or cerebral ischaemic events in patients with carotid artery stenosis. Randomised controlled trials on antithrombotic therapy for patients with minor ischaemic stroke and transient ischaemic attack (TIA) have recommended dual antiplatelet therapy (DAPT) in the three weeks following the index event. However, these trials excluded patients undergoing carotid revascularisation. To date, the optimal antithrombotic therapy during the peri-operative period of carotid endarterectomy (CEA) remains unclear.
Source: European Journal of Vascular and Endovascular Surgery - August 28, 2022 Category: Surgery Authors: Simone J.A. Donners, Joost M. Mekke, Eline S. van Hattum, Raechel J. Toorop, Gert J. de Borst, Dutch Audit for Carotid Interventions (DACI) Collaborators Source Type: research

Editor's Choice – Risk of Bleeding Complications With Different Peri-Operative Antithrombotic Regimens During Carotid Endarterectomy: a National Registry Analysis
Antithrombotic therapy is one of the cornerstones of the prevention of (recurrent) ocular or cerebral ischaemic events in patients with carotid artery stenosis. Randomised controlled trials on antithrombotic therapy for patients with minor ischaemic stroke and transient ischaemic attack (TIA) have recommended dual antiplatelet therapy (DAPT) in the three weeks following the index event. However, these trials excluded patients undergoing carotid revascularisation. To date, the optimal antithrombotic therapy during the peri-operative period of carotid endarterectomy (CEA) remains unclear.
Source: European Journal of Vascular and Endovascular Surgery - August 28, 2022 Category: Surgery Authors: Simone J.A. Donners, Joost M. Mekke, Eline S. van Hattum, Raechel J. Toorop, Gert J. de Borst, Dutch Audit for Carotid Interventions (DACI) Collaborators Source Type: research

A Composite Measure for Quality of Care in Patients with Symptomatic Carotid Stenosis Using Textbook Outcome.
CONCLUSION: In the Netherlands, most patients treated by CEA achieve TO. Variation between hospitals in achieving TO might imply differences in performance. TO may be used as an additive to the pre-existing IOM, especially in surgical care with low baseline risk such as CEA. PMID: 32732140 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - July 26, 2020 Category: Surgery Authors: Kuhrij LS, Karthaus EG, Vahl AC, Willems MCM, Elshof JW, de Borst GJ, Dutch Audit for Carotid Interventions (DACI) Group, DACI Collaborators Tags: Eur J Vasc Endovasc Surg Source Type: research

The Dutch Audit of Carotid Interventions: Transparency in Quality of Carotid Endarterectomy in Symptomatic Patients in the Netherlands.
CONCLUSION: CEA in The Netherlands is associated with an overall low mortality and (major) stroke/death rate. Whereas the indicator time to intervention varied between hospitals, mortality and (major) stroke/death were not significantly distinctive enough to identify worse practices and therefore were unsuitable for hospital comparison in the Dutch setting. Additionally, predictors of major stroke/death at population level could be identified. PMID: 30077438 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - August 1, 2018 Category: Surgery Authors: Karthaus EG, Vahl A, Kuhrij LS, Elsman BHP, Geelkerken RH, Wouters MWJM, Hamming JF, de Borst GJ, Dutch Society of Vascular Surgery, Steering Committee of the Dutch Audit for Carotid Interventions, Dutch Institute for Clinical Auditing Tags: Eur J Vasc Endovasc Surg Source Type: research

The Dutch Audit of Carotid Interventions: Transparency in Quality of Carotid Endarterectomy in Symptomatic Patients in the Netherlands
This study describes the design of the DACI and results of patients with a symptomatic stenosis undergoing carotid endarterectomy (CEA). It aimed to evaluate variation between hospitals in process of care and (adjusted) outcomes, as well as predictors of major stroke/death after CEA.
Source: European Journal of Vascular and Endovascular Surgery - August 1, 2018 Category: Surgery Authors: Eleonora G. Karthaus, Anco Vahl, Laurien S. Kuhrij, Bernard H.P. Elsman, Robert H. Geelkerken, Michel W.J.M. Wouters, Jaap F. Hamming, Gert J. de Borst, the Dutch Society of Vascular Surgery, the Steering Committee of the Dutch Audit for Carotid Intervent Source Type: research

Hospital costs of ischemic stroke and TIA in the Netherlands
Conclusions: Hospital costs are higher for inpatients and ischemic strokes compared with outpatients and TIAs, with length of stay (LOS) the most important contributor. LOS and hospital costs have substantially declined over the last 10 years, possibly due to improved hospital stroke care and efficient integrated stroke services.
Source: Neurology - June 1, 2015 Category: Neurology Authors: Buisman, L. R., Tan, S. S., Nederkoorn, P. J., Koudstaal, P. J., Redekop, W. K. Tags: Cost effectiveness/economic, Medical care, Infarction ARTICLE Source Type: research