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Total 12 results found since Jan 2013.

P005/44 Using the pEGASUS-stent with antithrombogenic properties and single antiplatelet therapy in a case of thrombectomy
IntroductionRescue stenting is used more and more in stroke cases with large-vessel-occlusion or medium-vessel-occlusion refractory to mechanical thrombectomy. The pEGASUS-stent(Phenox) represents a device which is equipped with a hydrophilic polymer coating(HPC) with antithrombogenic properties. The coating allows for implantation under single antiplatelet therapy, thus possibly reducing the risk of bleeding in acute stroke cases.Case HistoryA 79-year-old woman was rushed to emergency room due to left-sided hemiparesis and National-Institutes-of-Health-Stroke-Scale(NIHSS) of 14. Computed-tomography-image showed an occlusi...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Krug, N., Schulze-Zachau, V., Ntoulias, N., Psychogios, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

E-023 Predictors of outcomes in tandem anterior circulation occlusions following mechanical thrombectomy
In this study, we present outcomes of patients undergoing tandem mechanical thrombectomy. We demonstrate that stenting is associated with improved final reperfusion, but increased odds of asymptomatic ICH. Additional clinical trials should be performed to optimize the procedure and improve patient outcomes.Disclosures J. Catapano: None. D. Farhadi: None. A. Naik: None. S. Koester: None. E. Winkler: None. V. Srinivasan: None. K. Karahalios: None. J. Rulney: None. S. Desai: None. A. Jadhav: None. F. Albuquerque: None. A. Ducruet: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Catapano, J., Farhadi, D., Naik, A., Koester, S., Winkler, E., Srinivasan, V., Karahalios, K., Rulney, J., Desai, S., Jadhav, A., Albuquerque, F., Ducruet, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Clinical study of stent forming for symptomatic internal carotid artery stenosis
Stroke is one of the diseases that seriously threaten the survival and health of human beings. In Europe and the United States, stroke is the second leading cause of death after heart disease and tumors.[1] Stroke is also one of the fatal diseases in Asian countries. On average, about 1.5 million new stroke patients are added each year in China, and the incidence of stroke is increasing year by year. About 80% of all stroke patients are ischemic stroke, and symptomatic internal carotid atherosclerotic stenosis is another important cause of ischemic stroke. Ipsilateral carotid stenosis ≥50% increases the incidence of tran...
Source: Medicine - June 19, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

12 Innovations That Will Change Health Care and Medicine in the 2020s
Pocket-size ultrasound devices that cost 50 times less than the machines in hospitals (and connect to your phone). Virtual reality that speeds healing in rehab. Artificial intelligence that’s better than medical experts at spotting lung tumors. These are just some of the innovations now transforming medicine at a remarkable pace. No one can predict the future, but it can at least be glimpsed in the dozen inventions and concepts below. Like the people behind them, they stand at the vanguard of health care. Neither exhaustive nor exclusive, the list is, rather, representative of the recasting of public health and medic...
Source: TIME: Health - October 25, 2019 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized HealthSummit19 technology Source Type: news

Intracranial mechanical thrombectomy without extracranial revascularization for a tandem occlusion with robust Circle of Willis: case report
Publication date: Available online 4 October 2019Source: Interdisciplinary NeurosurgeryAuthor(s): Mateja de Leonni Stanonik, Christopher Sy, Cameron McDougall, Lee Birnbaum, Justin MascitelliAbstractA 59-year-old male presented with a severe left middle cerebral artery (MCA) syndrome, a National Institutes of Health Stroke Scale (NIHSS) of 17, and was last known well 26 hours prior. Computed tomography angiography (CTA) of the head demonstrated a tandem extracranial ICA and intracranial ICA/MCA occlusion. Computed tomography perfusion (CTP) demonstrated a large mismatch. The patient underwent a mechanical thrombectomy usin...
Source: Interdisciplinary Neurosurgery - October 4, 2019 Category: Neurosurgery Source Type: research

Comparison of 1-year clinical outcomes between prasugrel and ticagrelor versus clopidogrel in type 2 diabetes patients with acute myocardial infarction underwent successful percutaneous coronary intervention
Although the new oral P2Y12 inhibitors, prasugrel/ticagrelor have shown greater efficacy than clopidogrel in patients with the acute coronary syndrome, but they have not shown better efficacy in Korean patients. So we evaluated the efficacy of the prasugrel/ticagrelor in patients with myocardial infarction (MI) and diabetes, a more high-risk patients group. From the Korea Acute Myocardial Infarction Registry-National Institute of Health, 3985 patients with MI and diabetes who underwent PCI were enrolled between November 2011 and December 2015. The patients were divided into 2 groups: clopidogrel (n = 2985) and prasugr...
Source: Medicine - March 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Management of ruptured hidden mirror intracranial aneurysm during mechanical thrombectomy
Publication date: Available online 7 February 2019Source: Interdisciplinary NeurosurgeryAuthor(s): Kamil Zeleňák, Martin Vorčák, Ján Sýkora, Zuzana Trabalková, Jana Zeleňáková, Ema Kantorová, Vladimír NosáľAbstractA 55-year-old woman with acute ischaemic stroke was referred for endovascular treatment after unsuccessful intravenous thrombolysis. Her initial National Institutes of Health Stroke Score (NIHSS) was 20. The right carotid artery stenting was performed because of the inappropriate result of angioplasty of the right internal carotid artery stenosis at origin, followed by recanalization of right intern...
Source: Interdisciplinary Neurosurgery - February 8, 2019 Category: Neurosurgery Source Type: research

Compliant balloon angioplasty for the treatment of internal carotid artery dissection.
This report describes the innovative management of a severe haemodynamic stroke related to an occlusive extracranial internal carotid artery dissection. Intravenous thrombolysis combined with endovascular treatment were undertaken on the basis of a total mismatch profile (National Institutes of Health stroke scale (NIHSS) score of 27 and infarct volume on diffusion-weighted imaging of 0 mL). Balloon angioplasty using a long and compliant balloon microcatheter allowed complete recovery of the intracranial blood flow. The patient showed dramatic clinical improvement (day 1, NIHSS 5) and favourable functional outcome (day 9...
Source: Interventional Neuroradiology - September 1, 2018 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Alteplase for Acute Ischemic Stroke after Heparin Reversal with Protamine: A Case Report and Review
We describe the first reported case of a patient receiving full‐dose intravenous (IV) alteplase for AIS after heparin reversal with protamine. A 73‐year‐old man presented with AIS. He was treated with IV heparin, tirofiban, loading‐dose prasugrel, and aspirin before percutaneous coronary intervention (PCI) for placement of a right coronary artery stent. One hour following PCI, he abruptly developed left hemiparesis and dysphagia. The National Institutes of Health Stroke Scale was 12, and activated partial thromboplastin time (aPTT) was longer than 150 seconds. Head computed tomography (CT) showed no acute patholog...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 4, 2017 Category: Drugs & Pharmacology Authors: Gabriel V. Fontaine, Shawn M. Smith Tags: Case Report Source Type: research

Is There Benefit from Stenting on Cognitive Function in Intracranial Atherosclerosis
Background: Revascularization of stenotic cerebral arteries is hypothesized to improve cognition by increasing cerebral perfusion.Aims: We compared cognition impairment among patients treated with percutaneous angioplasty and stenting (PTAS) and aggressive medical management (AMM) versus AMM alone in the Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis (SAMMPRIS) Trial.Methods: In SAMMPRIS, 451 patients with recent transient ischemic attack or stroke attributed to 70-99% intracranial stenosis were randomized to PTAS plus AMM or AMM alone. Patients who had stroke as the qualifying event with Nat...
Source: Cerebrovascular Diseases - November 8, 2016 Category: Neurology Source Type: research

Treatment Trends In Management Of Intracranial Stenosis In The Pre- And Post-Sammpris Era (I8-1.008)
DISCUSSION: SAMMPRIS had a major impact on treatment trends of physicians managing patients with intracranial stenosis. In the Post-SAMMPRIS survey, 91% of respondents participating in SAMMPRIS and 82% of overall respondents indicated that the SAMMPRIS results changed the way they managed patients with ICAS.As aggressive medical management coupled with optimal risk factor reduction shows promise in reducing rates of recurrent stroke, a novel endovascular therapy will have to seek newer heights of increasing RRR to gain acceptance by practitioners.Disclosure: Dr. Pawar has nothing to disclose. Dr. Turan has received persona...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Pawar, S., Turan, T., Cotsonis, G., Lynn, M., Wooley, R., Stern, B., Derdeyn, C., Fiorella, D., Chimowitz, M. Tags: Clinical Decision Making After the Dust Settles on Clinical Trials Poster Presentations Source Type: research

Treatment Trends In Management Of Intracranial Stenosis In The Pre- And Post-Sammpris Era (P1.146)
DISCUSSION: SAMMPRIS had a major impact on treatment trends of physicians managing patients with intracranial stenosis. In the Post-SAMMPRIS survey, 91% of respondents participating in SAMMPRIS and 82% of overall respondents indicated that the SAMMPRIS results changed the way they managed patients with ICAS.As aggressive medical management coupled with optimal risk factor reduction shows promise in reducing rates of recurrent stroke, a novel endovascular therapy will have to seek newer heights of increasing RRR to gain acceptance by practitioners.Disclosure: Dr. Pawar has nothing to disclose. Dr. Turan has received persona...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Pawar, S., Turan, T., Cotsonis, G., Lynn, M., Wooley, R., Stern, B., Derdeyn, C., Fiorella, D., Chimowitz, M. Tags: Cerebrovascular Disease and Interventional Neurology: Intracranial Disease Source Type: research