• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Health Status, Late Effects and Long Term Survivorship of Allogeneic Bone Marrow Transplantation: A Retrospective Study
ConclusionThis study shows that allo‐HSCT recipients are living with high burdens of chronic diseases that warrant lifelong surveillance and engagement with healthcare. Structured, multi‐disciplinary care as recommended by published guidelines for allo‐HSCT survivors may reduce long term effects and improve their outcomes.
Source: Internal Medicine Journal - November 1, 2013 Category: Internal Medicine Authors: Grace Gifford, Joycelyn Sim, Annabel Horne, David Ma Tags: Original Article Source Type: research

Migration of Bone Marrow‐Derived Cells Into the Central Nervous System in Models of Neurodegeneration
This study confirms that BMDC infiltrate the CNS in animal models for stroke and Alzheimer's disease and that peripheral cells can be targeted to treat affected regions of the CNS. J. Comp. Neurol. 521:3863–3876, 2013. © 2013 Wiley Periodicals, Inc.
Source: The Journal of Comparative Neurology - October 7, 2013 Category: Neurology Authors: Antoine Lampron, Pedro M. Pimentel‐Coelho, Serge Rivest Tags: Cover Image Source Type: research

Percutaneous PFO closure for paradoxical stroke in 8‐kg twins
We present two cases of PFO closures in identical 8 kg twin boys with Hurler’s syndrome who had central lines for planned bone marrow transplants, with embolic stroke in one. We discuss the treatment options as well as the special challenges based on the patients’ age, size, and diagnoses. We also discuss the technical aspects and safety of percutaneous PFO closure. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - September 1, 2013 Category: Cardiovascular & Thoracic Surgery Authors: James Hill, Tamar Preminger Tags: Case Report Source Type: research

Development of psychological and intellectual performance in transplanted sickle cell disease patients: A prospective study from pretransplant period to 5years after HSCT.
CONCLUSION: At the end of follow-up, the patients improved their physical and psychological well-being. This allowed them to build projects for the future and to manifest the desire of becoming an adult. Bone marrow transplantation in this cohort of children with SCD and severe cerebral vasculopathy is associated with improved performance as measured by the Wechsler scale. PMID: 23769628 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - June 11, 2013 Category: Pediatrics Authors: Bockenmeyer J, Chamboredon E, Missud F, Benkerrou M, Holvoët L, Ithier G, Lescoeur B, Yakouben K, Ouachée-Chardin M, Rohrlich PS, Duval M, Baruchel A, Dalle JH Tags: Arch Pediatr Source Type: research

Migration of bone marrow‐derived cells into the CNS in models of neurodegeneration
This study confirms that bone marrow‐derived cells infiltrate the CNS in animal models for stroke and Alzheimer's disease and that peripheral cells can be targeted to treat affected regions of the CNS. J. Comp. Neurol., 2013. © 2013 Wiley Periodicals, Inc. Using a myeloablative chemotherapy regimen, the authors have investigated the capacity of bone marrow derived cells to enter into the central nervous system. These cells migrated specifically to sites of injuries in models of stroke and Alzheimer's disease but did not repopulate the entire parenchyma.
Source: The Journal of Comparative Neurology - May 16, 2013 Category: Neurology Authors: Antoine Lampron, Pedro M. Pimentel‐Coelho, Serge Rivest Tags: Research Article Source Type: research

Paradoxical protection from atherosclerosis and thrombosis in a mouse model of sickle cell disease
Summary Sickle cell disease (SCD) is associated with vascular complications including premature stroke. The role of atherothrombosis in these vascular complications is unclear. To determine the effect of SCD on atherosclerosis and thrombosis, mice with SCD along with controls were generated by transplantation of bone marrow from mice carrying the homozygous sickle cell mutation (Hbbhβs/hβs) or wild‐type mice (Hbb+/+) into C57BL6/J or apolipoprotein E deficient (Apoe−/−) recipient mice. At the time of sacrifice, 23–28 weeks following bone marrow transplantation, anaemia, reticulocytosis, and splenomegaly were pre...
Source: British Journal of Haematology - April 17, 2013 Category: Hematology Authors: Hui Wang, Wei Luo, Jintao Wang, Chiao Guo, Stephanie L. Wolffe, Julia Wang, Eddy B. Sun, Kori N. Bradley, Andrew D. Campbell, Daniel T. Eitzman Tags: Research Paper Source Type: research

Stem Cells for Cell-Based Therapies
The world of stem cells We know the human body comprises many cell types (e.g., blood cells, skin cells, cervical cells), but we often forget to appreciate that all of these different cell types arose from a single cell—the fertilized egg. A host of sequential, awe-inspiring events occur between the fertilization of an egg and the formation of a new individual: Embryonic stem (ES) cells are also called totipotent cells. The first steps involve making more cells by simple cell division: one cell becomes two cells; two cells become four cells, etc. Each cell of early development is undifferentiated; that is, it is...
Source: ActionBioscience - December 28, 2012 Category: Science Authors: Ali Hochberg Source Type: news

Pages: 1  2  3