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Total 6681 results found since Jan 2013.

Reperfusion Beyond 6 Hours Reduces Infarct Probability in Moderately Ischemic Brain Tissue Clinical Sciences
Conclusions— Brain tissue with mild to moderate ischemia can be salvaged by reperfusion even after 6 hours. Such tissue could be targeted for intervention beyond current treatment windows.
Source: Stroke - December 28, 2015 Category: Neurology Authors: An, H., Ford, A. L., Eldeniz, C., Chen, Y., Vo, K. D., Zhu, H., Powers, W. J., Lin, W., Lee, J.-M. Tags: Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Treatment, Ischemic Stroke Clinical Sciences Source Type: research

Patterns and Implications of Intracranial Arterial Remodeling in Stroke Patients Clinical Sciences
Conclusions— Intracranial arteries remodel in response to plaque formation, and posterior circulation arteries have a greater capacity for positive remodeling and, consequently, may more likely elude angiographic detection. Arterial remodeling may provide insight into stroke risk.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Qiao, Y., Anwar, Z., Intrapiromkul, J., Liu, L., Zeiler, S. R., Leigh, R., Zhang, Y., Guallar, E., Wasserman, B. A. Tags: Pathophysiology, Risk Factors, Computerized Tomography (CT), Imaging, Magnetic Resonance Imaging (MRI) Clinical Sciences Source Type: research

Letter by Reale et al Regarding Article, "Clinically Confirmed Stroke With Negative Diffusion-Weighted Imaging Magnetic Resonance Imaging: Longitudinal Study of Clinical Outcomes, Stroke Recurrence, and Systematic Review" Letters to the Editor
Source: Stroke - February 22, 2016 Category: Neurology Authors: Reale, G., Profice, P., Caliandro, P. Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Letters to the Editor Source Type: research

Clinical and Procedural Predictors of Outcomes From the Endovascular Treatment of Posterior Circulation Strokes Clinical Sciences
Conclusions— Time to the start of the procedure is an important predictor of clinical success after thrombectomy in patients with posterior circulation strokes. Both stent retriever and aspiration thrombectomy as primary treatment approaches are effective in achieving successful recanalization.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Mokin, M., Sonig, A., Sivakanthan, S., Ren, Z., Elijovich, L., Arthur, A., Goyal, N., Kan, P., Duckworth, E., Veznedaroglu, E., Binning, M. J., Liebman, K. M., Rao, V., Turner, R. D., Turk, A. S., Baxter, B. W., Dabus, G., Linfante, I., Snyder, K. V., Lev Tags: Cerebrovascular Disease/Stroke, Cerebrovascular Procedures Clinical Sciences Source Type: research

Fibroblast Growth Factor 23 Is Associated With Subclinical Cerebrovascular Damage: The Northern Manhattan Study Clinical Sciences
Conclusions— These cross-sectional community-based data from a diverse urban sample show an association between elevated FGF23 and small vessel disease and magnetic resonance imaging–defined brain infarction in men, independent of chronic kidney disease. Data on elevated FGF23 and subclinical cerebrovascular damage progression are needed.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Wright, C. B., Shah, N. H., Mendez, A. J., DeRosa, J. T., Yoshita, M., Elkind, M. S. V., Sacco, R. L., DeCarli, C., Rundek, T., Silverberg, S., Dong, C., Wolf, M. Tags: Growth Factors/Cytokines, Epidemiology, Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Brain activity underlying tool-related and imitative skills after major left hemisphere stroke
Apraxia is a debilitating cognitive motor disorder that frequently occurs after left hemisphere stroke and affects tool-associated and imitative skills. However, the severity of the apraxic deficits varies even across patients with similar lesions. This variability raises the question whether regions outside the left hemisphere network typically associated with cognitive motor tasks in healthy subjects are of additional functional relevance. To investigate this hypothesis, we explored regions where functional magnetic resonance imaging activity is associated with better cognitive motor performance in patients with left hem...
Source: Brain - April 25, 2016 Category: Neurology Authors: Martin, M., Nitschke, K., Beume, L., Dressing, A., Bühler, L. E., Ludwig, V. M., Mader, I., Rijntjes, M., Kaller, C. P., Weiller, C. Tags: CNS Injury and Stroke Original Articles Source Type: research

Stroke: Highlights of Selected Articles Stroke: Highlights of Selected Articles
Source: Stroke - June 26, 2016 Category: Neurology Tags: Stem Cells, Magnetic Resonance Imaging (MRI), Quality and Outcomes, Ischemic Stroke, Thrombosis Stroke: Highlights of Selected Articles Source Type: research

Cerebral Microbleeds and Cortical Superficial Siderosis in Patients Presenting With Minor Cerebrovascular Events Clinical Sciences
Conclusions— CMBs in TIA and minor stroke are moderately common but do not predict recurrence or 90-day outcome. CAA-related transient focal neurological episodes and TIA have overlapping clinical symptoms, suggesting that MRI may be needed for differentiation.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Zerna, C., Modi, J., Bilston, L., Shoamanesh, A., Coutts, S. B., Smith, E. E. Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Clinical Sciences Source Type: research

Gadolinium Enhancement in Intracranial Atherosclerotic Plaque and Ischemic Stroke: A Systematic Review and Meta-Analysis Stroke
Conclusions Intracranial plaque enhancement on high-resolution vessel wall MRI is strongly associated with ischemic stroke. Evaluation for plaque enhancement on MRI may be a useful test to improve diagnostic yield in patients with ischemic strokes of undetermined etiology.
Source: JAHA:Journal of the American Heart Association - August 14, 2016 Category: Cardiology Authors: Gupta, A., Baradaran, H., Al-Dasuqi, K., Knight-Greenfield, A., Giambrone, A. E., Delgado, D., Wright, D., Teng, Z., Min, J. K., Navi, B. B., Iadecola, C., Kamel, H. Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke, Atherosclerosis Source Type: research

Cerebral Small Vessel Disease Burden Is Increased in Systemic Lupus Erythematosus Clinical Sciences
This study aimed to determine the association between SLE and features on neuroimaging of cerebral small vessel disease (SVD), a risk factor for stroke.Methods—Consecutive patients attending a clinic for SLE were recruited. All patients underwent brain magnetic resonance imaging; had blood samples taken for markers of inflammation, endothelial dysfunction, cholesterol, and autoantibodies; and underwent cognitive and psychiatric testing. The data were compared with sex- and age-matched healthy controls and patients with minor stroke. Features of SVD were measured, a total SVD score calculated, and associations sought with...
Source: Stroke - October 23, 2016 Category: Neurology Authors: Wiseman, S. J., Bastin, M. E., Jardine, C. L., Barclay, G., Hamilton, I. F., Sandeman, E., Hunt, D., Amft, E. N., Thomson, S., Belch, J. F. F., Ralston, S. H., Wardlaw, J. M. Tags: Risk Factors, Imaging, Ischemic Stroke Original Contributions Source Type: research

Infarct Pattern and Collateral Status in Adult Moyamoya Disease Clinical Sciences
Conclusions—In the studied population of adult MMD patients, embolic phenomenon played an important role in ischemic stroke. Therapeutic strategies against thromboembolism, as well as collateral enhancing strategies targeting improvement of hemodynamic status or increased washout of emboli, are warranted.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Dong Yeop Kim, Jeong Pyo Son, Je Young Yeon, Gyeong-Moon Kim, Jong-Soo Kim, Seung-Chyul Hong, Oh Young Bang Tags: Mechanisms, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Moyamoya Original Contributions Source Type: research

Frequency and Predictors of Dysphagia in Patients With Recent Small Subcortical Infarcts Brief Report
Background and Purpose—Detailed data on the occurrence of swallowing dysfunction in patients with recent small subcortical infarcts (RSSI) in the context of cerebral small vessel disease are lacking. This prompted us to assess the frequency of and risk factors for dysphagia in RSSI patients.Methods—We identified all inpatients with magnetic resonance imaging–confirmed RSSI between January 2008 and February 2013. Demographic and clinical data were extracted from our stroke database, and magnetic resonance imaging scans were reviewed for morphological changes. Dysphagia was determined according to the Gugging Swallowin...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Simon Fandler, Thomas Gattringer, Sebastian Eppinger, Kathrin Doppelhofer, Daniela Pinter, Kurt Niederkorn, Christian Enzinger, Joanna M. Wardlaw, Franz Fazekas Tags: Magnetic Resonance Imaging (MRI), Complications, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Is Unexplained Early Neurological Deterioration After Intravenous Thrombolysis Associated With Thrombus Extension? Clinical Sciences
Conclusions—In this study, unexplained END occurring after thrombolysis was independently associated with susceptibility vessel sign extension, suggesting in situ thrombus extension or re-embolization. These findings strengthen the need to further investigate early post-thrombolysis administration of antithrombotics to reduce the risk of this ominous clinical event.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Pierre Seners, Robert Hurford, Marie Tisserand, Guillaume Turc, Laurence Legrand, Olivier Naggara, Jean-Louis Mas, Catherine Oppenheim, Jean-Claude Baron Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research

Procalcitonin and Midregional Proatrial Natriuretic Peptide as Biomarkers of Subclinical Cerebrovascular Damage Clinical Sciences
Conclusions—Higher concentrations of procalcitonin, a marker of infection, and MR-proANP, a marker of cardiac dysfunction, are independently associated with subclinical cerebrovascular damage. If further studies demonstrate an incremental value for risk stratification, biomarker-guided primary prevention studies may lead to new approaches to prevent cerebrovascular disease.
Source: Stroke - February 26, 2017 Category: Neurology Authors: Mira Katan, Yeseon Moon, Arnold von Eckardstein, Kathartina Spanaus, Janet DeRosa, Jose Gutierrez, Charles DeCarli, Clinton Wright, Ralph Sacco, Mitchell Elkind Tags: Biomarkers, Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Cognitive Impairment Original Contributions Source Type: research