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Percutaneous coronary intervention versus coronary artery bypass graft for stable angina: Meta-regression of randomized trials
Conclusion: PCI significantly reduces the risk of stroke compared to CABG particularly in female patients: however the risk of revascularization is increased with PCI, especially in women and in those with diabetes.
Source: Contemporary Clinical Trials - May 1, 2014 Category: Radiology Authors: Fabrizio D'Ascenzo, Umberto Barbero, Claudio Moretti, Tullio Palmerini, Diego Della Riva, Andrea Mariani, Pierluigi Omedè, James J. DiNicolantonio, Giuseppe Biondi-Zoccai, Fiorenzo Gaita Tags: Study Design, Statistical Design, Study Protocols Source Type: research

Cardiac function assessed by exercise echocardiography on the first morning after coronary artery bypass grafting
Summary Cardiac surgery patients are urged to resume light physical activity on the first postoperative day, even if cardiac function may not have recovered fully after the operation. To elucidate the postoperative recovery process, we examined cardiac surgery patients with exercise echocardiography before and on the first day after the operation. Patients undergoing on‐pump coronary artery bypass grafting were examined with echocardiography during semirecumbent cycle exercise. Patients exercised for five minutes at 10 W intensity and five minutes at 30 W intensity in bed with the upper body supported to approximately ...
Source: Clinical Physiology and Functional Imaging - December 23, 2014 Category: Radiology Authors: Hans Henrik Dedichen, Idar Kirkeby‐Garstad, Petter Aadahl, Jonny Hisdal, Brage H. Amundsen Tags: Original Article Source Type: research

Speckle-Tracking Imaging to Monitor Myocardial Function After Coronary Artery Bypass Graft Surgery
Conclusions— Based on the results of our study in all age groups, speckle-tracking imaging parameters are more effective than the LVEF, left ventricular end-diastolic dimension, and stroke volume for monitoring improvement in myocardial function after CABG surgery.
Source: Journal of Ultrasound in Medicine - October 23, 2013 Category: Radiology Authors: Yin, Z.-Y., Li, X.-F., Tu, Y.-F., Dong, D.-D., Zhao, D.-L., Shen, B. Tags: Original Research Source Type: research

The early diastolic myocardial velocity: a marker of increased risk in patients with coronary heart disease
ConclusionEm appears to be a sensitive echocardiographic index in identifying non‐diabetic patients with AMI at risk of new cardiovascular events.
Source: Clinical Physiology and Functional Imaging - December 3, 2013 Category: Radiology Authors: Jonas Johnson, Aristomenis Manouras, Fredrik Bergholm, Lars Åke Brodin, Stefan Agewall, Loghman Henareh Tags: Original Article Source Type: research

Maximum plaque height in carotid ultrasound predicts cardiovascular disease outcomes: a population-based validation study of the American society of echocardiography ’s grade II–III plaque characterization and protocol
AbstractThe presence of carotid arterial plaque by ultrasound enhances cardiovascular risk stratification beyond traditional risk factors. However, plaque quantification techniques require further outcomes-based investigation. The purpose of this study was to evaluate the utility of a focused carotid ultrasound protocol and novel plaque grading system developed by the American Society of Echocardiography (ASE). A retrospective analysis of 514 outpatients who were referred for coronary angiography between 2011 and 2014 was performed using a province-sponsored health database. All participants prospectively received a focuse...
Source: The International Journal of Cardiovascular Imaging - January 27, 2021 Category: Radiology Source Type: research

Ticagrelor Effects on Myocardial Infarction and the Impact of Event Adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) Trial
ConclusionsIn patients with ACS, ticagrelor significantly reduced the incidence of MI compared with clopidogrel, with consistent results across most MI subtypes. CEC procedures identified more MI endpoints compared with site investigators. (A Comparison of Ticagrelor [AZD6140] and Clopidogrel in Patients With Acute Coronary Syndrome [PLATO]; NCT00391872)
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - April 14, 2014 Category: Radiology Source Type: research

Long-Term Mortality After Coronary Revascularization in Nondiabetic Patients With Multivessel Disease
This study performed a patient-level meta-analysis to compare the effect of CABG versus PCI with drug-eluting stents on long-term mortality in 1,275 nondiabetic patients with multivessel CAD.MethodsIndividual patient data from the SYNTAX (Synergy between PCI with Taxus and Cardiac Surgery) and the BEST (Randomized Comparison of Coronary Artery Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients with Multivessel Coronary Artery Disease) trials were pooled. The primary outcome was death from any cause.ResultsThe median follow-up time was 61 months (interquartile range: 50 months to 62 month...
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - June 27, 2016 Category: Radiology Source Type: research

Medical Treatment and Revascularization Options in Patients With Type 2 Diabetes and Coronary Disease
This study determined the effect of optimal medical therapy (OMT), with or without percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), on long-term outcomes with respect to LVEF and number of diseased vessels, including proximal left anterior descending artery involvement.MethodsA patient-level pooled analysis was undertaken in 3 federally-funded trials. The primary endpoint was the composite of death, myocardial infarction (MI), or stroke, adjusted for trial and randomization strategy.ResultsAmong 5,034 subjects, 15% had LVEF  
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - August 29, 2016 Category: Radiology Source Type: research

Left Main Coronary Artery Disease Secular Trends in Patient Characteristics, Treatments,  and Outcomes
Left main coronary artery (LMCA) disease is the highest-risk lesion subset of ischemic heart disease, and has traditionally been an indication for coronary artery bypass grafting (CABG). Recent evidence suggests comparable clinical outcomes between percutaneous coronary intervention (PCI) and CABG for LMCA disease, with similar rates of mortality and serious composite outcomes, a higher rate of stroke with CABG, and a higher rate of repeat revascularization with PCI. These results have been translated to the current guideline recommendation that PCI is a reasonable alternative to CABG in patients with low to intermediate a...
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - September 5, 2016 Category: Radiology Source Type: research

Progression of CAC Score and Risk of Incident CVD
Conclusions Although CAC progression was independently, but modestly, associated with CVD outcomes, this relationship was no longer significant when including follow-up CAC in the model. These findings imply that if serial CAC scanning is performed, the latest scan should be used for risk assessment, and in this context, CAC progression provides no additional prognostic information.
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - November 30, 2016 Category: Radiology Authors: Radford, N. B., DeFina, L. F., Barlow, C. E., Lakoski, S. G., Leonard, D., Paixao, A. R. M., Khera, A., Levine, B. D. Tags: Original Research Source Type: research

Subclinical markers of cardiovascular disease predict adverse outcomes in chronic kidney disease patients with normal left ventricular ejection fraction
AbstractEmerging cardiovascular biomarkers, such as speckle tracking echocardiography (STE) and aortic pulse wave velocity (aPWV), have recently demonstrated the presence of subclinical left ventricular dysfunction and arterial stiffening in patients with chronic kidney disease (CKD) and no previous cardiovascular history. However, limited information exists on the prognostic impact of these biomarkers. We aimed to investigate whether STE and aPWV predict major adverse cardiac events (MACE) in this patient population. In this cohort study we prospectively analysed 106 CKD patients with no overt cardiovascular disease (CVD)...
Source: The International Journal of Cardiovascular Imaging - January 23, 2017 Category: Radiology Source Type: research

Severe loss of right ventricular longitudinal contraction occurs after cardiopulmonary bypass in patients with preserved right ventricular output
AbstractAssessment of right ventricular (RV) function is crucial since RV failure with a reduced cardiac output (CO) is associated with compromised outcome in cardiac surgery. Echocardiographic evaluation of RV function is commonly used, but a reduction in tricuspid annular plane systolic excursion (TAPSE) and tricuspid annulus tissue Doppler imaging (S ′) have been observed independently of clinical signs of RV failure. This has led to uncertainty of these variables’ validity in cardiac surgery. To describe transesophageal echocardiographic (TEE) measures of RV function during coronary artery bypass graft surgery with...
Source: The International Journal of Cardiovascular Imaging - May 1, 2019 Category: Radiology Source Type: research