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Source: The American Journal of Cardiology
Procedure: Coronary Artery Bypass Graft
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Total 37 results found since Jan 2013.
Relation Between Preoperative Renal Dysfunction and Cardiovascular Events (Stroke, Myocardial Infarction, or Heart Failure or Death) Within Three Months of Isolated Coronary Artery Bypass Grafting
Renal dysfunction is related to long-term mortality and myocardial infarction after coronary artery bypass grafting (CABG). We aimed to investigate the association between preoperative renal dysfunction and early risk of stroke, myocardial infarction, or heart failure after CABG. From the Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies registry, we included all 36,284 patients who underwent primary isolated CABG from 2000 to 2008 in Sweden. The Swedish National Inpatient Registry was used to obtain the primary end point, which was rehos...
Source: The American Journal of Cardiology - July 18, 2013 Category: Cardiology Authors: Martin J. Holzmann, Ulrik Sartipy Tags: Coronary Artery Disease Source Type: research
Predictors of Stroke Associated with Coronary Artery Bypass Grafting in Patients with Diabetes Mellitus and Multivessel Coronary Artery Disease
This study assesses demographic and clinical variables associated with perioperative and late stroke in diabetes mellitus patients following multivessel coronary artery bypass grafting (CABG). FREEDOM is the largest randomized trial of diabetic patients undergoing multivessel CABG. FREEDOM patients had improved survival free of death, myocardial infarction or stroke and increased overall survival following CABG compared to percutaneous intervention (PCI). However, the stroke rate was greater following CABG than PCI.
Source: The American Journal of Cardiology - February 20, 2015 Category: Cardiology Authors: Michael J. Domanski, Michael E. Farkouh, Victor Zak, Steven Feske, Donald Easton, Jesse Weinberger, Martial Hamon, Jorge Escobedo, Peter Shrader, Flora S. Siami, Valentin Fuster Source Type: research
Periprocedural Stroke After Coronary Revascularization (From the CREDO-Kyoto PCI/CABG Registry Cohort-3)
There is a scarcity of data on incidence, risk factors, especially clinical severity, and long-term prognostic impact of periprocedural stroke after coronary revascularization in contemporary real-world practice. Among 14867 consecutive patients undergoing first coronary revascularization between January 2011 and December 2013 (percutaneous coronary intervention [PCI]: N=13258, and coronary artery bypass grafting [CABG]: N=1609) in the CREDO-Kyoto PCI/CABG registry Cohort-3, we evaluated the details on periprocedural stroke.
Source: The American Journal of Cardiology - December 3, 2020 Category: Cardiology Authors: Ko Yamamoto, Masahiro Natsuaki, Takeshi Morimoto, Hiroki Shiomi, Yukiko Matsumura-Nakano, Kenji Nakatsuma, Hiroki Watanabe, Erika Yamamoto, Eri Kato, Masayuki Fuki, Kyohei Yamaji, Ryusuke Nishikawa, Kazuya Nagao, Yasuaki Takeji, Hirotoshi Watanabe, Junich Source Type: research
Comparison of Intermediate-Term Outcomes of Coronary Artery Bypass Grafting Versus Drug-Eluting Stents for Patients ≥75 Years of Age
In conclusion, older patients experienced similar mortality and stroke/MI/mortality rates for CABG and PCI with DES, although repeat revascularization rates were higher for patients undergoing PCI with DES.
Source: The American Journal of Cardiology - December 16, 2013 Category: Cardiology Authors: Edward L. Hannan, Ye Zhong, Peter B. Berger, Gary Walford, Jeptha P. Curtis, Chuntao Wu, Ferdinand J. Venditti, Robert S.D. Higgins, Craig R. Smith, Stephen J. Lahey, Spencer B. King Tags: Coronary Artery Disease Source Type: research
Relation of Major Depression to Survival After Coronary Artery Bypass Grafting
In conclusion, we found a strong and significant association between depression and long-term survival in patients with established ischemic heart disease who underwent CABG. Depression was also associated with an increased risk for a combination of death or rehospitalization for heart failure, myocardial infarction, or stroke.
Source: The American Journal of Cardiology - June 20, 2014 Category: Cardiology Authors: Malin Stenman, Martin J. Holzmann, Ulrik Sartipy Tags: Coronary Artery Disease Source Type: research
Meta-Analysis of Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting in Left Main Coronary Arterial Disease
Despite the increase in use of percutaneous coronary intervention (PCI) in left main (LM) coronary disease, its efficacy compared with coronary artery bypass grafting (CABG) is unclear. We performed a meta-analysis of randomized controlled trials to assess the optimal revascularization strategy. Our search yielded 8 studies reporting relevant outcomes which were pooled using the inverse-variance method, and the hazard ratio (HR) was calculated. The primary outcome was all-cause mortality, myocardial infarction (MI), or stroke (MACE), and the secondary outcome was death/MI/stroke/repeat revascularization (expanded MACE).
Source: The American Journal of Cardiology - March 28, 2017 Category: Cardiology Authors: Abdur R. Khan, Harsh Golwala, Avnish Tripathi, Haris Riaz, Arnav Kumar, Michael P. Flaherty, Deepak L. Bhatt Source Type: research
Prehospitalization Antiplatelet Therapy and Outcomes After Saphenous Vein Graft Intervention
In conclusion, prehospital use of antiplatelet therapy was associated with a lower occurrence of major adverse cardiac events after SVG intervention. We did not find that DAPT improved outcomes compared to single antiplatelet therapy.
Source: The American Journal of Cardiology - October 26, 2012 Category: Cardiology Authors: Ralf E. Harskamp, Marcel A. Beijk, Peter Damman, Jan G. Tijssen, Renato D. Lopes, Robbert J. de Winter Tags: Coronary Artery Disease Source Type: research
Alice in Wonderland of Drug-Eluting Stent for Unprotected Left Main Disease
We read the recent meta-analysis by Jang et al of 3 randomized trials and 9 observational studies (with 5,079 patients) comparing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus coronary artery bypass grafting (CABG) for unprotected left main coronary artery (ULMCA) disease. At 1-year follow-up, there were trends toward lower risk for death (odds ratio [OR] 0.68, 95% confidence interval [CI] 0.45 to 1.02, p = 0.06) and the composite end point of death, myocardial infarction, or stroke (OR 0.70, 95% CI 0.49 to 1.00, p = 0.05) in the DES group compared to the CABG group. However, target vess...
Source: The American Journal of Cardiology - March 15, 2013 Category: Cardiology Authors: Hisato Takagi, Takuya Umemoto Tags: Readers' Comments Source Type: research
Development and Validation of a Cardiovascular Risk Assessment Model in Patients With Established Coronary Artery Disease
In conclusion, in patients with established coronary artery disease, the risk of cardiovascular mortality during longer term follow-up can be adequately predicted using the clinical characteristics available at baseline. However, the prediction of nonfatal outcomes, both separately and combined with fatal outcomes, poses major challenges for clinicians and model developers.
Source: The American Journal of Cardiology - April 3, 2013 Category: Cardiology Authors: Linda Battes, Rogier Barendse, Ewout W. Steyerberg, Maarten L. Simoons, Jaap W. Deckers, Daan Nieboer, Michel Bertrand, Roberto Ferrari, Willem J. Remme, Kim Fox, Johanna J.M. Takkenberg, Eric Boersma, Isabella Kardys Tags: Coronary Artery Disease Source Type: research
Comparison of the Efficacy and Safety of Two Rivaroxaban Doses in Acute Coronary Syndrome (from ATLAS ACS 2–TIMI 51)
In conclusion, the 2 doses of rivaroxaban reduced cardiovascular events in patients with recent acute coronary syndromes treated with antiplatelet therapies; however, the 2.5-mg dose was associated with lower mortality and fewer bleeding complications than the 5-mg dose. Thus, the addition of rivaroxaban 2.5 mg twice daily offers a more favorable balance of efficacy and safety in patients with recent acute coronary syndromes.
Source: The American Journal of Cardiology - May 28, 2013 Category: Cardiology Authors: Jessica L. Mega, Eugene Braunwald, Stephen D. Wiviott, Sabina A. Murphy, Alexei Plotnikov, Nina Gotcheva, Mikhail Ruda, C. Michael Gibson Tags: Coronary Artery Disease Source Type: research
Comparison by Meta-Analysis of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With a Mean Age of ≥70 Years
A paucity of published data evaluating the outcomes of older patients (age ≥70 years) undergoing revascularization for unprotected left main coronary artery disease is available. We performed aggregate data meta-analyses of the clinical outcomes (all-cause mortality, nonfatal myocardial infarction, stroke, repeat revascularization, and major adverse cardiac and cerebrovascular events at 30 days and 12 and 22 months) in studies comparing percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients with a mean age of ≥70 years and unprotected left main coronary artery disease. A compre...
Source: The American Journal of Cardiology - May 31, 2013 Category: Cardiology Authors: Mahboob Alam, Salim S. Virani, Saima A. Shahzad, Sahar Siddiqui, Khaleeq H. Siddiqui, Shahzad A. Mumtaz, Neal S. Kleiman, Joseph S. Coselli, Nasser M. Lakkis, Hani Jneid Tags: Coronary Artery Disease Source Type: research
Contemporary Analysis of Incidence and Outcomes of Stent Thrombosis Presenting as ST Elevation Myocardial Infarction in a Primary Percutaneous Coronary Intervention Cohort
There are limited data about the effectiveness of primary percutaneous coronary intervention (PPCI) for stent thrombosis treatment. We aimed to evaluate the prevalence and outcomes of PPCI in patients with ST elevation acute myocardial infarction (STEMI) due to stent thrombosis, and comparing the outcomes with patients treated for de novo coronary thrombosis. This was an observational cohort study of 2,935 patients who underwent PPCI from 2003 to 2011 with follow-up for a median of 3.0 years (interquartile range 1.2 to 4.6). The primary end point was the first major adverse cardiac event (MACE) defined as death, nonfatal ...
Source: The American Journal of Cardiology - September 9, 2013 Category: Cardiology Authors: Daniel A. Jones, Sean Gallagher, Krishnaraj S. Rathod, Mohammed Akhtar, Charles J. Knight, Martin T. Rothman, Akhil Kapur, Anthony Mathur, Ajay K. Jain, Adam D. Timmis, Elliot J. Smith, Andrew Wragg Tags: Coronary Artery Disease Source Type: research
Association Between Intraprocedural Thrombotic Events and Adverse Outcomes After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction (a Harmonizing Outcomes With RevasculariZatiON and Stents in Acute Myocardial Infarction HORIZONS-AMI Substudy)
The present study sought to determine the extent to which adverse angiographic events encountered during percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI) are associated with adverse clinical outcomes. Patients with STEMI represent a cohort at particularly high risk of intraprocedural thrombotic events (IPTEs). The overall frequency and implications of IPTEs occurring in patients with STEMI have not been systematically quantified in previous studies. A total of 3,163 patients undergoing primary percutaneous coronary intervention with stent implantation for STEMI in the Harmonizing Ou...
Source: The American Journal of Cardiology - October 28, 2013 Category: Cardiology Authors: Ajay J. Kirtane, Prabhdeep Sandhu, Roxana Mehran, Margaret McEntegart, Ecaterina Cristea, Sorin J. Brener, Ke Xu, Martin Fahy, Philippe Généreux, Jeffrey D. Wessler, Gregg W. Stone Tags: Coronary Artery Disease Source Type: research
Minimal Changes in Postoperative Creatinine Values and Early and Late Mortality and Cardiovascular Events After Coronary Artery Bypass Grafting
In conclusion, already a minimal increase in the postoperative serum creatinine level after CABG was independently associated with long-term all-cause mortality and cardiovascular outcomes, regardless of preoperative renal function.
Source: The American Journal of Cardiology - October 30, 2013 Category: Cardiology Authors: Marcus Liotta, Daniel Olsson, Ulrik Sartipy, Martin J. Holzmann Tags: Coronary Artery Disease Source Type: research
Usefulness of Brachial Artery Flow-Mediated Dilation to Predict Long-Term Cardiovascular Events in Subjects Without Heart Disease
Endothelial dysfunction is considered an important prognostic factor in atherosclerosis. To determine the long-term association of brachial artery flow-mediated dilation (FMD) and adverse cardiovascular (CV) events in healthy subjects, we prospectively assessed brachial FMD in 618 consecutive healthy subjects with no apparent heart disease, 387 men (63%), and mean age 54 ± 11 years. After overnight fasting and discontinuation of all medications for ≥12 hours, FMD was assessed using high-resolution linear array ultrasound. Subjects were divided into 2 groups: FMD ≤11.3% (n = 309) and>11.3% (n = 309), where 11.3% is...
Source: The American Journal of Cardiology - October 28, 2013 Category: Cardiology Authors: Michael Shechter, Alon Shechter, Nira Koren-Morag, Micha S. Feinberg, Liran Hiersch Tags: Miscellaneous Source Type: research
