Meta-Analysis of Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting in Left Main Coronary Arterial Disease

Despite the increase in use of percutaneous coronary intervention (PCI) in left main (LM) coronary disease, its efficacy compared with coronary artery bypass grafting (CABG) is unclear. We performed a meta-analysis of randomized controlled trials to assess the optimal revascularization strategy. Our search yielded 8 studies reporting relevant outcomes which were pooled using the inverse-variance method, and the hazard ratio (HR) was calculated. The primary outcome was all-cause mortality, myocardial infarction (MI), or stroke (MACE), and the secondary outcome was death/MI/stroke/repeat revascularization (expanded MACE).
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research