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Vagus nerve stimulation paired with tactile training improved sensory function in a chronic stroke patient.
CONCLUSIONS: Sensory function significantly improved in this man following VNS paired with tactile stimulation. This approach merits further study in controlled clinical trials. PMID: 29562561 [PubMed - in process]
Source: NeuroRehabilitation - March 28, 2018 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Effect of vagus nerve stimulation paired with rehabilitation for upper limb function improvement after stroke: a systematic review and meta-analysis of randomized controlled trials
Vagus nerve stimulation (VNS) could potentially facilitate arm function recovery after stroke. The aim of this review was to evaluate the effect of VNS paired with rehabilitation on upper limb function recovery after stroke. We considered randomized controlled trials (RCTs) that used VNS paired with rehabilitation for the improvement of upper limb function after stroke and were published in English. Eligible RCTs were identified by searching electronic databases, including MEDLINE, Web of Science, Embase, CENTRAL and PEDro, from their inception until June 2021. Quality of included studies was assessed using PEDro score and...
Source: International Journal of Rehabilitation Research - May 15, 2022 Category: Rehabilitation Tags: Review Articles Source Type: research

Vagus Nerve Stimulation Paired With Upper-Limb Rehabilitation After Stroke: 2- and 3-Year Follow-up From the Pilot Study
More than 50% of people post-stroke have significant limitations in their ability to carry out day-to-day functional activities long term and are unable to effectively incorporate their impaired hand and arm during everyday tasks.1,2 The disabling effects typically persist for many years after the initial stroke.3,4 People with stroke often compensate by using the less impaired limb for daily activities, which may precipitate learned non-use and result in further deterioration of arm and hand function.
Source: Archives of Physical Medicine and Rehabilitation - March 29, 2023 Category: Rehabilitation Authors: Gerard E. Francisco, Navzer D. Engineer, Jesse Dawson, Teresa J. Kimberley, Steven C. Cramer, Cec ília N. Prudente, David Pierce, W. Brent Tarver, Reema H. Adham Hinds, Ann Van de Winckel, Nuray Yozbatiran Tags: ORIGINAL RESEARCH Source Type: research

Efficacy and safety of vagus nerve stimulation on upper extremity motor function in patients with stroke: A meta-analysis of randomized controlled trials
CONCLUSION: For stroke victims with upper limb disabilities, VNS paired with rehabilitation was significantly safe and effective. More high-quality multicentric RCTs are needed to validate this conclusion.PMID:37694313 | DOI:10.3233/NRE-230106
Source: NeuroRehabilitation - September 11, 2023 Category: Rehabilitation Authors: Tianqi We Xiangyang Ge Lingfeng Lu Jing Li Panpan Xu Qinfeng Wu Source Type: research

Vagus Nerve Stimulation Paired with Upper-Limb Rehabilitation After Stroke: Two- and Three-Year Follow-up from the Pilot Study
More than 50% of people post-stroke have significant limitations in their ability to carry out day-to-day functional activities long term and are unable to effectively incorporate their impaired hand and arm during everyday tasks1,2. The disabling effects typically persist for many years after the initial stroke3,4. People with stroke often compensate by using the less impaired limb for daily activities, which may precipitate learned non-use and result in further deterioration of arm and hand function5.
Source: Archives of Physical Medicine and Rehabilitation - March 29, 2023 Category: Rehabilitation Authors: Gerard E. Francisco, Navzer Engineer, Jesse Dawson, Teresa J. Kimberley, Steven Cramer, Cec ília N. Prudente, David Pierce, Brent W. Tarver, Reema H. Adham Hinds, Ann Van de Winckel, Nuray Yozbatiran Tags: Original Research Source Type: research

Neurostimulation After Stroke
This article explores its applications in upper and lower limb stroke rehabilitation. The authors review various methods to target the corticomotor system, including transcranial direct current stimulation, repetitive transcranial magnetic stimulation, and vagus nerve stimulation. In addition, the authors review the use of peripheral neuromuscular electrical stimulation for therapeutic and assistive purposes, including transcutaneous electrical nerve stimulation, neuromuscular electrical stimulation, and functional electrical stimulation. For each, the authors examine the potential benefits, limitations, safety considerations, and FDA status.
Source: Physical Medicine and Rehabilitation Clinics of North America - August 21, 2023 Category: Rehabilitation Authors: Hala Osman, Ricardo Siu, Nathan S. Makowski, Jayme S. Knutson, David A. Cunningham Source Type: research

Characterization of an Algorithm for Autonomous, Closed-Loop Neuromodulation During Stroke Rehabilitation
Main Objective: To characterize a novel algorithm capable of triggering Vagus Nerve Stimulation (VNS) on large movements during post-stroke physical rehabilitation.Secondary Objective: To investigate a set of parameters that optimizes triggering rate and movement selectivity for the novel algorithm.
Source: Archives of Physical Medicine and Rehabilitation - September 28, 2021 Category: Rehabilitation Authors: Joseph Epperson, Eric Meyers, David Pruitt, Joel Wright, Michael Kilgard, Seth Hays Tags: Research Poster 1710197 Source Type: research

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