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Specialty: Hematology
Infectious Disease: COVID-19
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Total 85 results found since Jan 2013.
Platelets and COVID-19
Hamostaseologie. 2021 Oct;41(5):379-385. doi: 10.1055/a-1581-4355. Epub 2021 Oct 25.ABSTRACTIn 2019 first reports about a new human coronavirus emerged, which causes common cold symptoms as well as acute respiratory distress syndrome. The virus was identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe thrombotic events including deep vein thrombosis, pulmonary embolism, and microthrombi emerged as additional symptoms. Heart failure, myocardial infarction, myocarditis, and stroke have also been observed. As main mediator of thrombus formation, platelets became one of the key aspects in SARS-C...
Source: Hamostaseologie - October 25, 2021 Category: Hematology Authors: Anne-Katrin Rohlfing Dominik Rath Tobias Geisler Meinrad Gawaz Source Type: research
Thrombogenicity markers for early diagnosis and prognosis in COVID-19: a change from the current paradigm?
Standard biomarkers have been widely used for COVID-19 diagnosis and prognosis. We hypothesize that thrombogenicity metrics measured by thromboelastography will provide better diagnostic and prognostic utility versus standard biomarkers in COVID-19 positive patients. In this observational prospective study, we included 119 hospitalized COVID-19 positive patients and 15 COVID-19 negative patients. On admission, we measured standard biomarkers and thrombogenicity using a novel thromboelastography assay (TEG-6s). In-hospital all-cause death and thrombotic occurrences (thromboembolism, myocardial infarction and stroke) were re...
Source: Blood Coagulation and Fibrinolysis - November 19, 2021 Category: Hematology Tags: ORIGINAL ARTICLES Source Type: research
Cerebral Venous Thrombosis
Semin Thromb Hemost DOI: 10.1055/s-0042-1742738Cerebral venous thrombosis (CVT) is a rare form of stroke that often affects younger age groups, especially reproductive age group females. CVT is a potentially fatal neurological condition that can be frequently overlooked due to the vague nature of its clinical and radiological presentation. Headache is the most common presenting symptom. However, a wide range of symptoms can be present and the symptom onset can be acute, subacute, or chronic. Neuroimaging is mandatory in cases where CVT is suspected. Both magnetic resonance venography and computed tomography venography can ...
Source: Seminars in Thrombosis and Hemostasis - February 15, 2022 Category: Hematology Authors: Aamodt, Anne Hege Skatt ør, Thor Håkon Tags: Review Article Source Type: research
Arterial Thrombotic Events in Hospitalized COVID-19 Patients: A Short Review and Meta-Analysis
In conclusion, we found a non-negligible proportion of ATE in patients hospitalized for COVID-19. Our results are similar to those found in hospitalized patients with influenza or with non-COVID viral pneumonia. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Seminars in Thrombosis and Hemostasis - July 6, 2022 Category: Hematology Authors: Candeloro, Matteo Schulman, Sam Tags: Review Article Source Type: research
Erythrocyte aggregation in sudden flow arrest is linked to hyperthermia, hypoxemia and band 3 availability
CONCLUSIONS: We show that the C-terminal domain of band 3 plays a pivotal role in RBC aggregation. Further, aggregation is enhanced by hyperthermia and hypoxemia.PMID:35841276 | DOI:10.1111/jth.15821
Source: Thrombosis and Haemostasis - July 16, 2022 Category: Hematology Authors: Samantha Weber-Fishkin Harrison S Seidner Geoffrey Gunter Mary D Frame Source Type: research
The long haul COVID-19 arterial thrombosis
The presence of a coexisting hypercoagulable state associated with Covid-19 infection has gained attention and several studies have already described acute limb ischemia (ALI) and peripheral arterial disease in critically ill patients, as well as coronary artery disease and ischemic stroke as manifestations usually associated with respiratory distress. Actually no information is currently available on how long inflammation and thrombotic derangements can last after recovery from Covid-19 symptoms and which patients are prone to develop acute arterial thrombosis.
Source: Thrombosis Research - July 26, 2022 Category: Hematology Authors: Maria Pia Borrelli, Adelaide Buora, Paolo Frigatti Tags: Letter to the Editors-in-Chief Source Type: research
Hereditary thrombotic thrombocytopenic purpura and COVID-19: Impacts of vaccination and infection in this rare disease
DISCUSSION: The risk of an acute episode triggered by COVID-19 seems higher than following vaccination in hTTP patients, who can be safely vaccinated against SARS-CoV-2.PMID:36284639 | PMC:PMC9585384 | DOI:10.1002/rth2.12814
Source: Thrombosis and Haemostasis - October 26, 2022 Category: Hematology Authors: Erika Tarasco Anne Sophie von Krogh Radomira Hrdlickova Thomas R Braschler Teresa Iwaniec Paul N Kn öbl Eriko Hamada Oleg Pikovsky Stefan Farese Odit Gutwein Petr Kessler Nina H Schultz Charis von Auer Jerzy Windyga Kenneth Friedman Ingrid Hrachovinova J Source Type: research
Thrombosis and bleeding in patients with COVID-19 requiring extracorporeal membrane oxygenation: a systematic review and meta-analysis
CONCLUSIONS: Circuit thrombosis and major bleeding were the most common thrombotic and bleeding events. The incidence of ICH was significantly higher when ECMO was indicated for COVID-19 than for other respiratory diseases. There is no evidence for stronger anticoagulation practice, and remains no consistent anticoagulation strategy to reduce the occurrence of thrombosis and bleeding under the double "hit" of COVID-19 and ECMO.PMID:36999123 | PMC:PMC9993729 | DOI:10.1016/j.rpth.2023.100103
Source: Thrombosis and Haemostasis - March 31, 2023 Category: Hematology Authors: Yu Jin Yang Zhang Jinping Liu Zhou Zhou Source Type: research
Prevention of Venous Thromboembolism in Medical Patients with Thrombocytopenia or with Platelet Dysfunction: The Last 10 Years
Semin Thromb Hemost DOI: 10.1055/s-0043-1769013Current guideline recommendations for primary prophylaxis of venous thromboembolism (VTE) are based on randomized clinical trials that usually exclude subjects at a potentially high risk of bleeding complications. For this reason, no specific guideline is available for thromboprophylaxis in hospitalized patients with thrombocytopenia and/or platelet dysfunction. However, except in patients with absolute contraindications to anticoagulant drugs, antithrombotic prophylaxis should always be considered, for example, in hospitalized cancer patients with thrombocytopenia, especially...
Source: Seminars in Thrombosis and Hemostasis - May 18, 2023 Category: Hematology Authors: Tufano, Antonella Brenner, Benjamin Tags: Review Article Source Type: research
