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Total 4983 results found since Jan 2013.

Management and outcome of patients with acute ischemic stroke and tandem carotid occlusion in the ESCAPE-NA1 trial
Conclusions Tandem cervical carotid occlusion in patients with acute large vessel stroke did not lower the odds of good functional outcome in our study. Functional outcomes were similar irrespective of the management of the cervical ICA occlusion (stenting vs not stenting).
Source: Journal of NeuroInterventional Surgery - April 19, 2022 Category: Neurosurgery Authors: Marko, M., Cimflova, P., Poppe, A. Y., Kashani, N., Singh, N., Ospel, J., Mayank, A., van Adel, B., McTaggart, R. A., Nogueira, R. G., Demchuk, A. M., Rempel, J. L., Joshi, M., Zerna, C., Menon, B. K., Tymianski, M., Hill, M. D., Goyal, M., Almekhlafi, M. Tags: Ischemic stroke Source Type: research

Operator assessment versus core laboratory adjudication of recanalization following endovascular treatment of acute ischemic stroke: a systematic review and meta-analysis
Conclusion Operator angiographic reads are statistically significantly higher than core laboratory-read readings following stroke thrombectomy, especially for complete recanalization. These differences should be considered when interpreting reports of angiographic outcomes after thrombectomy.
Source: Journal of NeuroInterventional Surgery - January 11, 2023 Category: Neurosurgery Authors: Ibrahim, M. K., Shehata, M. A., Ghozy, S., Bilgin, C., Jabal, M. S., Heiferman, D. M., Kadirvel, R., Kallmes, D. F. Tags: Ischemic stroke Source Type: research

Endovascular thrombectomy beyond 24 hours from ischemic stroke onset: a propensity score matched cohort study
Conclusion In this real world study, EVT beyond 24 hours from stroke onset or last known well appeared to be feasible, with comparable safety and functional outcomes to EVT initiation between 6 and 24 hours. Randomized trials assessing the efficacy of EVT in the VL window are warranted, but may only be feasible with a large international collaborative approach.
Source: Journal of NeuroInterventional Surgery - February 14, 2023 Category: Neurosurgery Authors: Dhillon, P. S., Butt, W., Podlasek, A., Barrett, E., McConachie, N., Lenthall, R., Nair, S., Malik, L., James, M. A., Dineen, R. A., England, T. J. Tags: Ischemic stroke Source Type: research

Early and Continuous Neurologic Improvements after Intravenous Thrombolysis Are Strong Predictors of Favorable Long-term Outcomes in Acute Ischemic Stroke
Background: Intravenously administered tissue plasminogen activator (IV tPA) remains the only approved therapeutic agent for arterial recanalization in acute ischemic stroke (AIS). Considerable proportion of AIS patients demonstrate changes in their neurologic status within the first 24 hours of intravenous thrombolysis with IV tPA. However, there are little available data on the course of clinical recovery in subacute 2- to 24-hour window and its impact. We evaluated whether neurologic improvement at 2 and 24 hours after IV tPA bolus can predict functional outcomes in AIS patients at 3 months.Methods: Data for consecutive...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Leonard LL. Yeo, Prakash Paliwal, Hock L. Teoh, Raymond C. Seet, Bernard PL. Chan, Benjamin Wakerley, Shen Liang, Rahul Rathakrishnan, Vincent F. Chong, Eric YS. Ting, Vijay K. Sharma Tags: Original Articles Source Type: research

Clinical Use of Computed Tomographic Perfusion for the Diagnosis and Prediction of Lesion Growth in Acute Ischemic Stroke
Conclusions: In real-world use, acute imaging with CTP did not predict stroke or DWI lesions with sufficient accuracy. Our findings argue against the use of CTP for screening AIS patients until real-world implementations match the accuracy reported from specialized research centers.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Branko N. Huisa, William P. Neil, Ronald Schrader, Marcel Maya, Benedict Pereira, Nhu T. Bruce, Patrick D. Lyden Tags: Original Articles Source Type: research

Assessment of Arterial Collateralization and Its Relevance to Intra-arterial Therapy for Acute Ischemic Stroke
Evidence from recent randomized controlled studies comparing intra-arterial (IA) therapy with intravenous tissue plasminogen activator highlighted the mismatch between recanalization success and clinical outcomes in patients presenting with acute ischemic stroke. There is emerging interest in the impact of arterial collateralization, as determined by leptomeningeal anastomoses (LMAs), on the treatment outcomes of IA therapy. The system of LMA constitutes the secondary network of cerebral collateral circulation apart from the Circle of Willis. Both anatomic and angiographic studies confirmed significant interindividual vari...
Source: Journal of Stroke and Cerebrovascular Diseases - April 18, 2013 Category: Neurology Authors: Siva Seeta Ramaiah, Peter Mitchell, Richard Dowling, Bernard Yan Tags: Review Articles Source Type: research

Angiographic outcome of endovascular stroke therapy correlated with MR findings, infarct growth, and clinical outcome in the DEFUSE 2 trial
ConclusionThrombolysis in cerebral infarction reperfusion following endovascular therapy for ischemic stroke is highly correlated with magnetic resonance imaging reperfusion, infarct growth, and clinical outcome.
Source: International Journal of Stroke - March 31, 2014 Category: Neurology Authors: Michael P. Marks, Maarten G. Lansberg, Michael Mlynash, Stephanie Kemp, Ryan A. McTaggart, Greg Zaharchuk, Roland Bammer, Gregory W. Albers, Tags: Research Source Type: research

Epidemiology of Moyamoya Disease in Taiwan: A Nationwide Population-Based Study Clinical Sciences
Conclusions— The incidence of moyamoya disease has increased in adults but not in children from 2000 to 2011 in Taiwan. Sex ratio and comorbid conditions differed by age and study period.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Chen, P.-C., Yang, S.-H., Chien, K.-L., Tsai, I.-J., Kuo, M.-F. Tags: Cerebrovascular disease/stroke, Epidemiology Clinical Sciences Source Type: research

Prediction of recanalization in acute stroke patients receiving intravenous and endovascular revascularization therapy
ConclusionThe overall likelihood of recanalization was the highest in the endovascular group, and higher for intravenous thrombolysis compared with no revascularization therapy. However, our statistical models of recanalization for each individual patient indicate significant variability between treatment options, suggesting the need to include this prediction in the personalized treatment selection.
Source: International Journal of Stroke - June 30, 2014 Category: Neurology Authors: Guangming Zhu, Patrik Michel, Tudor Jovin, James T. Patrie, Wenjun Xin, Ashraf Eskandari, Weiwei Zhang, Max Wintermark Tags: Research Source Type: research

Noncardiogenic Stroke Patients with Metabolic Syndrome Have More Border-zone Infarction and Intracranial Artery Stenosis
Little is known about the clinical character of stroke patients with metabolic syndrome (MetS) in Chinese population. In this hospital-based cross-sectional study, we elucidated the prevalence of MetS among patients with acute noncardiogenic cerebral infarction from south China, the topographic infarction patterns in magnetic resonance imaging, and vascular angiography findings of stroke patients with MetS.
Source: Journal of Stroke and Cerebrovascular Diseases - January 2, 2015 Category: Neurology Authors: Zheng Zhang, Meijuan Xiao, Zusen Ye, Wanli Zhang, Bin Han, Youcheng Li Source Type: research

Endovascular treatment of tandem vascular occlusions in acute ischemic stroke
Conclusions Our study shows preliminary data from three centers on recanalization of tandem occlusions in patients presenting with AIS. There was a preference to revascularize the proximal occlusion using a stent followed by distal recanalization with mechanical thrombectomy, intra-arterial thrombolysis or a combination of these. This approach has low periprocedural complications and can achieve an excellent angiographic and clinical outcome.
Source: Journal of NeuroInterventional Surgery - February 12, 2015 Category: Neurosurgery Authors: Puri, A. S., Kuhn, A. L., Kwon, H.-J., Khan, M., Hou, S. Y., Lin, E., Chueh, J., van der Bom, I. M., Dabus, G., Linfante, I., Gounis, M. J., Wakhloo, A. K. Tags: Ischemic stroke Source Type: research

Frequency of New Pulmonary Neoplasm Incidentally Detected by Computed Tomography Angiography in Acute Stroke Patients—A Single-Center Study
Incidental findings of suspect lung opacities are common in computed tomography (CT)–based thorax examinations, especially in high-risk patients, such as stroke patients. Screening with CT of the thorax has detected lung cancer in approximately .31%-1.20% of high-risk populations. The aim of the present study was to report the frequency of suspect lung opacities on routine acute stroke imaging.
Source: Journal of Stroke and Cerebrovascular Diseases - March 25, 2015 Category: Neurology Authors: Line Bentsen, Anders Christensen, Inger Havsteen, Hanne Hansen, Christian Ovesen, Hanne Christensen Source Type: research

Value of utilizing both ASPECTS and CT angiography collateral score for outcome prediction in acute ischemic stroke
ConclusionsOutcome predictability improves when using ASPECTS and CTA‐CS together.
Source: International Journal of Stroke - April 23, 2015 Category: Neurology Authors: Dongbeom Song, Kijeong Lee, Eun Hye Kim, Young Dae Kim, Jinkwon Kim, Tae‐Jin Song, Hye Sun Lee, Hyo Suk Nam, Ji Hoe Heo Tags: Research Source Type: research

A Case of Recurrent Ischemic Stroke Involving Subacute, Progressive Intracranial Cerebral Arterial Sclerosis Prior to Diagnosis with -mutated Polycythemia Vera
A 58-year-old man presenting with no vascular risk factors visited our hospital with right hemiparesis and total aphasia. Diffusion-weighted magnetic resonance imaging of the brain showed multiple hyperintensities in watershed distributions in the left hemisphere. Magnetic resonance angiography (MRA) revealed stenosis of the middle cerebral artery, despite normal MRA findings 2 months prior. One year after the first stroke, the patient experienced a recurrent ischemic stroke involving the left anterior choroidal artery, pulmonary embolism, and deep venous thrombosis.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2015 Category: Neurology Authors: Tomohisa Nezu, Shiro Aoki, Kazuhide Ochi, Sayaka Sugihara, Tetsuya Takahashi, Naohisa Hosomi, Hirofumi Maruyama, Masayasu Matsumoto Tags: Case Studies Source Type: research

Congenital Spinal Malformation and Stroke: Aneurysmal Dilatations and Bilateral Rotational Vertebral Artery Occlusion
A 30-year-old woman suffered from acute vertebrobasilar stroke. Cranial tomography (CT) scans showed multiple vertebral abnormalities suggestive of congenital spine malformation, and angiographic CT revealed aneurysmal dilatations (ADs) at segment V2 of both vertebral arteries (VAs). Dynamic neuroimaging tests including angiography and angio-CT were performed and showed occlusion of both VAs at the point of the ADs with contralateral rotation of the neck. The presence of a bony structure causing the artery compression was excluded and embolic phenomena originating at the AD was proposed as the likely source of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - December 8, 2015 Category: Neurology Authors: Patricia de la Riva, Maria Teresa Martínez-Zabaleta, Edurne Pardo, Nicolás Samprón, Elisabet Mondragón-Rezola, Maialen Arruti González, Jose Ángel Larrea, José Félix Martí-Massó Tags: Case Studies Source Type: research