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ASPECT Score and Its Application to Vasospasm in Aneurysmal Subarachnoid Haemorrhage: a Case –Control Study
AbstractDelayed cerebral ischaemia (DCI) is a significant complication of aneurysmal subarachnoid haemorrhage (aSAH) and is strongly associated with poorer outcome. The Alberta Stroke Program Early Computer Tomography (ASPECT) score is an established scoring tool, used in acute ischaemic stroke, to quantify early ischaemic changes on CT head scans. We aim to identify if ASPECT scoring correlates with functional outcome in DCI following aSAH. Retrospective case –control study. Inclusion criteria: admission to the Department of Neurosurgery at Leeds Teaching Hospitals NHS Trust (a tertiary neurosurgical centre in the Unite...
Source: Translational Stroke Research - August 9, 2022 Category: Neurology Source Type: research

Inflammation-mediated vitamin K and vitamin D effects on vascular calcifications in people with HIV on active antiretroviral therapy
Background: People with HIV (PWH) experience increased systemic inflammation and monocyte activation, leading to increased risk of cardiovascular events (death, stroke, and myocardial infarction) and higher coronary artery calcium scores (CACs). Vitamins D and K2 have significant anti-inflammatory effects; in addition, vitamin K2 is involved in preventing vascular calcifications in the general population. The roles of vitamins D and K in increased coronary calcifications in successfully treated PWH is less understood. Methods: We prospectively recruited 237 PWH on antiretroviral treatment (ART) and 67 healthy co...
Source: AIDS - March 25, 2022 Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research

Apical Lung Exam on CTA Aids COVID-19 Screen in Stroke Patients
THURSDAY, Oct. 29, 2020 -- For patients presenting with acute ischemic stroke (AIS), apical lung assessment on computed tomography angiography (CTA) may be useful as part of the screening approach for COVID-19, according to a study published online...
Source: Drugs.com - Pharma News - October 29, 2020 Category: Pharmaceuticals Source Type: news

First Automated Stroke Imaging Evaluation via Electronic Alberta Stroke Program Early CT Score in a Mobile Stroke Unit
Conclusions: This study on the integration of e-ASPECTS into the prehospital stroke management via a MSU showed for the first time that such integration is feasible, and aids both decision regarding the treatment option and the triage regarding the most appropriate target hospital.Cerebrovasc Dis 2016;42:332-338
Source: Cerebrovascular Diseases - June 15, 2016 Category: Neurology Source Type: research

Otitis Media Leads to Brain Abscess Presenting as Stroke
By Mikhail Elfond, DO; Esi Quayson, MD; & Joseph V.M. Kelly, MD, MBA   A 65-year-old man presented to the ED via EMS with symptoms of stroke. The paramedics stated his right-sided weakness and speech difficulty started 40 minutes prior to presentation in the ED. En route to the hospital, paramedics observed four episodes of facial twitching.     Vitals signs were significant for a rectal temperature of 100.2°F and a fingerstick blood sugar of 220 mg/dL. History of present illness was significant for a diagnosis of left otitis media treated with Augmentin and Vicodin at an urgent care center one day prior to prese...
Source: The Case Files - January 20, 2015 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Addition of Hyperacute MRI Aids in Patient Selection, Decreasing the Use of Endovascular Stroke Therapy Clinical Sciences
Conclusions— Implementation of hyperacute MRI protocol decreases the number of endovascular stroke interventions by half. Further investigation of MRI use for patient selection is warranted.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Wisco, D., Uchino, K., Saqqur, M., Gebel, J. M., Aoki, J., Alam, S., George, P., Newey, C. R., Man, S., Tateishi, Y., McNeil, J., Winfield, M., Cheng-Ching, E., Hui, F. K., Toth, G., Bain, M., Rasmussen, P. A., Masaryk, T., Ruggieri, P., Hussain, M. S. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research