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Total 2168 results found since Jan 2013.

Type I Thyroplasty Is Safe in Patients Undergoing Antithrombotic Therapy
Conclusion: Type I thyroplasty with careful pre- and postoperative management is safe in patients undergoing antithrombotic therapy.ORL
Source: ORL - April 26, 2023 Category: ENT & OMF Source Type: research

Increased major bleeding incidence in atrial fibrillation patients with apixaban: a review of Japanese post-marketing surveillance studies of direct oral anticoagulants
AbstractLarge-scaled post-marketing surveillance studies (PMSSs) of 4 direct oral anticoagulants (DOACs) for stroke prevention in non-valvular atrial fibrillation (AF) were conducted since 2011 in Japan, and the results of the last one have recently been published. Each reported a more than acceptable ischemic stroke prevention. The major bleeding rates were also acceptably low and comparable to each other in the PMSSs of dabigatran (J-dabigatran), rivaroxaban (XAPASS), and edoxaban (ETNA-AF-Japan). However, the incidence in PMSS of apixaban (STANDARD) was more than double the others. This finding appeared to contradict th...
Source: European Journal of Clinical Pharmacology - April 25, 2023 Category: Drugs & Pharmacology Source Type: research

Prescription patterns and therapeutic effects of second-line drugs in Japanese patients with type 2 diabetes mellitus: Analysis of claims data for metformin and dipeptidyl peptidase-4 inhibitors as the first-line hypoglycemic agents
CONCLUSIONS: Metformin was suggested to have larger effect to reduce death than sulfonylurea in patients receiving first-line DPP4i. The order of first- and second-line for the DPP4i and metformin combination did not affect the outcomes. Given the nature of the study design, certain limitations, including potential under-adjustment for confounders, should be considered.PMID:37096493 | DOI:10.1080/14656566.2023.2206016
Source: Expert Opinion on Pharmacotherapy - April 25, 2023 Category: Drugs & Pharmacology Authors: Rimei Nishimura Tomomi Takeshima Kosuke Iwasaki Sumiko Aoi Source Type: research

History of Carotid Artery Reconstruction around the World and in Japan
Neurol Med Chir (Tokyo). 2023 Apr 20. doi: 10.2176/jns-nmc.2022-0362. Online ahead of print.ABSTRACTSince ancient times, physicians have been aware of correlations between the carotid artery and consciousness; however, carotid stenosis was only recently identified as the cause of atherothrombotic ischemic stroke. In 1658, Wepfer described the first suggestion of a link between symptoms of cerebral arterial insufficiency and carotid pathology. In 1951, Fisher reported details of the symptoms and pathological findings and emphasized that cervical atheromatous lesions induced cerebral infarction with various symptoms. The beg...
Source: Neurologia Medico-Chirurgica - April 21, 2023 Category: Neurosurgery Authors: Masaaki Uno Source Type: research

Significance of coronary artery calcification for predicting major adverse cardiovascular events: results from the NADESICO study in Japan
CONCLUSIONS: Adding assessment of Agatston CAC scores to Suita score was useful to improve the predictive ability for future MACE in Japanese patients. Agatston CAC scores of ≥100 or 200 in male and ≥ 400 in female patients in addition to Suita score improved the MACE risk prediction.PMID:37085027 | DOI:10.1016/j.jjcc.2023.04.006
Source: Journal of Cardiology - April 21, 2023 Category: Cardiology Authors: Shinichi Wada Yoshitaka Iwanaga Michikazu Nakai Yoko M Nakao Yoshihiro Miyamoto Teruo Noguchi NADESICO Study Investigators Source Type: research

History of Carotid Artery Reconstruction around the World and in Japan
Neurol Med Chir (Tokyo). 2023 Apr 20. doi: 10.2176/jns-nmc.2022-0362. Online ahead of print.ABSTRACTSince ancient times, physicians have been aware of correlations between the carotid artery and consciousness; however, carotid stenosis was only recently identified as the cause of atherothrombotic ischemic stroke. In 1658, Wepfer described the first suggestion of a link between symptoms of cerebral arterial insufficiency and carotid pathology. In 1951, Fisher reported details of the symptoms and pathological findings and emphasized that cervical atheromatous lesions induced cerebral infarction with various symptoms. The beg...
Source: Neurologia Medico-Chirurgica - April 21, 2023 Category: Neurosurgery Authors: Masaaki Uno Source Type: research