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How AI Is Changing Medical Imaging to Improve Patient Care
That doctors can peer into the human body without making a single incision once seemed like a miraculous concept. But medical imaging in radiology has come a long way, and the latest artificial intelligence (AI)-driven techniques are going much further: exploiting the massive computing abilities of AI and machine learning to mine body scans for differences that even the human eye can miss. Imaging in medicine now involves sophisticated ways of analyzing every data point to distinguish disease from health and signal from noise. If the first few decades of radiology were about refining the resolution of the pictures taken of...
Source: TIME: Health - November 4, 2022 Category: Consumer Health News Authors: Alice Park and Video by Andrew D. Johnson Tags: Uncategorized Frontiers of Medicine 2022 healthscienceclimate Innovation sponsorshipblock Source Type: news

Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer
We examined associations of biomarkers of oxidative stress (myeloperoxidase, growth differentiation factor-15, 8-hydroxy-2'-deoxyguanosine [8-OH-dG], placental growth factor), cardiac injury (troponin I, cystatin-C), inflammation (interleukin-6, C-reactive protein), and myocardial fibrosis (transforming growth factor-ß) with long-term RICVD in breast cancer (BC) survivors. We conducted a nested case-control study within the Women's Health Initiative of postmenopausal women with incident BC stages I-III, who received radiation and had pre- and post-BC diagnosis serum samples. Cases (n = 55) were defined as developing incid...
Source: Cancer Control - September 30, 2022 Category: Cancer & Oncology Authors: Alexi Vasbinder Richard K Cheng Susan R Heckbert Hilaire Thompson Oleg Zaslavksy Rowan T Chlebowski Aladdin H Shadyab Lisa Johnson Jean Wactawski-Wende Gretchen Wells Rachel Yung Lisa Warsinger Martin Electra D Paskett Kerryn Reding Source Type: research

Breast cancer survivors with preserved or rescued cardiorespiratory fitness have similar cardiac, pulmonary and muscle function compared to controls
AbstractBreast cancer survivors (BCS) have a high prevalence of cardiovascular disease and low cardiorespiratory fitness (CRF). CRF is an important predictor of survival in BCS. However, the physiological factors that contribute to low CRF in BCS have not been completely elucidated. To assess differences in physiological factors (cardiac, pulmonary, muscle function) related to CRF between BCS and controls. Twenty-three BCS and 23 age-body mass index (BMI) matched controls underwent a peak cycling exercise test to determine CRF, with physiological factors measured at resting and at peak exercise. Cardiac hemodynamics (strok...
Source: European Journal of Applied Physiology - September 16, 2022 Category: Physiology Source Type: research

Mutation of breast cancer susceptibility genes increases cerebral microbleeds: A pilot study
Growing evidence suggests breast cancer susceptibility gene (BRCA) mutations may augment cerebrovascular risk factors. With this influence in mind, we aimed to identify if BRCA mutations increased the prevalence of cerebral small vessel disease (CSVD).
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2022 Category: Neurology Authors: Brandon Pope, Zoe Wolcott, Marissa Castillo, Jacqueline Jin, Ka-Ho Wong, Adam de Havenon, Shadi Yaghi, Eric D. Goldstein Source Type: research

Prevalence of Cardiovascular Diseases Among Breast Cancer Survivors: Findings From the NHANES 2003-2018
CONCLUSION: Our findings suggest that BC survivors are at risk of suffering from CVD and public health strategies for the long-term management of CVD risk factors in this vulnerable population group is recommended.PMID:35975972 | DOI:10.1177/08901171221120910
Source: American Journal of Health Promotion : AJHP - August 17, 2022 Category: International Medicine & Public Health Authors: Youngdeok Kim R Lee Franco Alexander R Lucas Arnethea L Sutton Jessica G LaRose Jonathan Kenyon Jeremy Via Richard K Cheng Ralph B D'Agostino Vanessa B Sheppard W Gregory Hundley Source Type: research

Effectiveness and implementation of SHared decision-making supported by OUTcome information among patients with breast cancer, stroke and advanced kidney disease: SHOUT study protocol of multiple interrupted time series
Introduction Within the value-based healthcare framework, outcome data can be used to inform patients about (treatment) options, and empower them to make shared decisions with their health care professional. To facilitate shared decision-making (SDM) supported by outcome data, a multicomponent intervention has been designed, including patient decision aids on the organisation of post-treatment surveillance (breast cancer); discharge location (stroke) and treatment modality (advanced kidney disease), and training on SDM for health care professionals. The SHared decision-making supported by OUTcome information (SHOUT) study ...
Source: BMJ Open - August 1, 2022 Category: General Medicine Authors: Hackert, M. Q. N., Ankersmid, J. W., Engels, N., Prick, J. C. M., Teerenstra, S., Siesling, S., Drossaert, C. H. C., Strobbe, L. J. A., van Riet, Y. E. A., van den Dorpel, R. M. A., Bos, W. J. W., van der Nat, P. B., van den Berg-Vos, R. M., van Schaik, S Tags: Open access, Health services research Source Type: research

Oncological Benefit versus Cardiovascular Risk in Breast Cancer Patients Treated with Modern Radiotherapy
J Clin Med. 2022 Jul 4;11(13):3889. doi: 10.3390/jcm11133889.ABSTRACTRadiotherapy (RT) is an essential part of breast cancer (BC) treatments. Unfortunately, heart exposure to radiation can also impair the long-term survival of patients. Our study aimed to quantify the oncological benefit and the cardiovascular (CV) risk associated with modern RT in a real-world cohort of BC patients. Our descriptive study enrolled BC patients who received adjuvant RT. Ten-year overall survival (OS) was estimated using Predict® version 2.1 (National Health Service, London, UK). The basal risk of CV events was estimated using the American H...
Source: Clinical Breast Cancer - July 9, 2022 Category: Cancer & Oncology Authors: Francisco Acevedo Teresa Ip Mar ía Orellana Gonzalo Mart ínez Luigi Gabrielli Marcelo Andia Cecilia Besa Mauricio P Pinto Cesar S ánchez Tomas Merino Source Type: research