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Nutrition: Sodium Chloride
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Total 383 results found since Jan 2013.
Excess salt intake promotes M1 microglia polarization via a p38/MAPK/AR-dependent pathway after cerebral ischemia in mice.
In conclusion, HSD promotes polarization in pro-inflammatory M1 microglia by upregulating the expression of the AR protein via p38/MAPK, thereby exacerbating the development of ischemia stroke.
PMID: 32044667 [PubMed - as supplied by publisher]
Source: International Immunopharmacology - February 6, 2020 Category: Allergy & Immunology Authors: Zhang T, Wang D, Li X, Jiang Y, Wang C, Zhang Y, Kong Q, Tian C, Dai Y, Zhao W, Jiang M, Chang Y, Wang G Tags: Int Immunopharmacol Source Type: research
24-h urinary sodium excretion and the risk of adverse outcomes.
Conclusion: High sodium intake is associated with an increased incidence of CVD and DM.
PMID: 32602794 [PubMed - as supplied by publisher]
Source: Annals of Medicine - July 2, 2020 Category: Internal Medicine Tags: Ann Med Source Type: research
Cinnamon May Slow Progression To Type 2 Diabetes, Boston Study Finds
(CNN) — Cinnamon may improve blood sugar control in people with a condition known as prediabetes and may slow the progression to type 2 diabetes, according to a new pilot study of 51 people with elevated blood sugars.
“We are looking for safe, durable and cost-effective approaches to reduce the progression from prediabetes to type 2 diabetes,” said study author Dr. Giulio Romeo, a staff physician at Boston’s Joslin Diabetes Center and the division of endocrinology at Beth Israel Deaconess Medical Center. The study published Tuesday in the Journal of the Endocrine Society.
“Our 12-week study sh...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 21, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated CBSN Boston Cinnamon CNN Diabetes Source Type: news
20-HETE Enzymes and Receptors in the Neurovascular Unit: Implications in Cerebrovascular Disease
20-HETE is a potent vasoconstrictor that is implicated in the regulation of blood pressure, cerebral blood flow and neuronal death following ischemia. Numerous human genetic studies have shown that inactivating variants in the cytochrome P450 enzymes that produce 20-HETE are associated with hypertension, stroke and cerebrovascular disease. However, little is known about the expression and cellular distribution of the cytochrome P450A enzymes (CYP4A) that produce 20-HETE or the newly discovered 20-HETE receptor (GPR75) in the brain. The present study examined the cell types and regions in the rat forebrain that express CYP4...
Source: Frontiers in Neurology - September 3, 2020 Category: Neurology Source Type: research
Salt Substitute Cut Disease and Death Rates in Large Trial
A randomized trial recently reported in the New England Journal of Medicine focused on an important question for older adults with high blood pressure or a previous stroke: Can switching from regular salt to a 75% sodium chloride and 25% potassium chloride substitute help protect against stroke, major cardiovascular events, or death?
Source: JAMA - October 26, 2021 Category: General Medicine Source Type: research
Salt Substitute Reduces Mortality and Stroke in Older Adults Who Have a History or Are at Risk of Stroke
Am Fam Physician. 2022 Mar 1;105(3):322-323.NO ABSTRACTPMID:35289576
Source: American Family Physician - March 15, 2022 Category: Primary Care Authors: Mark H Ebell Source Type: research
