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Total 383 results found since Jan 2013.
Estimated burden of cardiovascular disease and value-based price range for evolocumab in a high-risk, secondary-prevention population in the US payer context.
CONCLUSION: Real-world CVD burden is substantial. Using the observed CVD burden in CPRD and the CTTC relationship, the cost-effectiveness analysis showed that, accounting for uncertainties, the expected value-based price for evolocumab is higher than its current annual cost as long as the payer discount off list price is greater than 20%.
PMID: 28097904 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - January 19, 2017 Category: Health Management Tags: J Med Econ Source Type: research
Global aphasia without hemiparesis may be caused by blunt head trauma: an adolescent boy with transient aphasia - Şahin S, Türkdoğan D, Hacıfazlıoğlu NE, Yalçın EU, Eksen ZY, Ekinci G.
We report a 15-year old boy with transient global aphasia without hemiparesis due...
Source: SafetyLit - January 25, 2017 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Simple and effective method to lower body core temperatures of hyperthermic patients - O'Connor JP.
Hyperthermia is a potentially life threatening scenario that may occur in patients due to accompanying morbidities, exertion, or exposure to dry and arid environmental conditions. In particular, heat stroke may result from environmental exposure combined w...
Source: SafetyLit - February 16, 2017 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
The impact of post-procedural complications on reimbursement, length of stay and mechanical ventilation among patients undergoing transcatheter aortic valve implantation in Germany
ConclusionsPost procedural complications such as bleeding events, acute kidney injuries and strokes are associated with increased resource use and substantial amounts of additional reimbursement in Germany, which has important implications for decision making outside of the usual clinical sphere.
Source: The European Journal of Health Economics - February 21, 2017 Category: Health Management Source Type: research
War during Childhood: The Long Run Effects of Warfare on Health
Publication date: Available online 7 March 2017 Source:Journal of Health Economics Author(s): Mevlude Akbulut-Yuksel This paper estimates the causal long-term consequences of an exposure to war in utero and during childhood on the risk of obesity and the probability of having a chronic health condition in adulthood. Using the plausibly exogenous city-by-cohort variation in the intensity of WWII destruction as a unique quasi-experiment, I find that individuals who were exposed to WWII destruction during the prenatal and early postnatal periods have higher BMIs and are more likely to be obese as adults. I also find an eleva...
Source: Journal of Health Economics - March 7, 2017 Category: Health Management Source Type: research
Vitamin C supplementation for the primary prevention of cardiovascular disease.
CONCLUSIONS: Currently, there is no evidence to suggest that vitamin C supplementation reduces the risk of CVD in healthy participants and those at increased risk of CVD, but current evidence is limited to one trial of middle-aged and older male physicians from the USA. There is limited low- and very low-quality evidence currently on the effect of vitamin C supplementation and risk of CVD risk factors.
PMID: 28301692 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - March 15, 2017 Category: Journals (General) Authors: Al-Khudairy L, Flowers N, Wheelhouse R, Ghannam O, Hartley L, Stranges S, Rees K Tags: Cochrane Database Syst Rev Source Type: research
Does my high blood pressure improve your survival? Overall and subgroup learning curves in health
Summary
Learning curves in health are of interest for a wide range of medical disciplines, healthcare providers, and policy makers. In this paper, we distinguish between three types of learning when identifying overall learning curves: economies of scale, learning from cumulative experience, and human capital depreciation. In addition, we approach the question of how treating more patients with specific characteristics predicts provider performance. To soften collinearity problems, we explore the use of least absolute shrinkage and selection operator regression as a variable selection method and Theil–Goldberger mixed es...
Source: Health Economics - April 27, 2017 Category: Health Management Authors: Raf Van Gestel, Tobias Müller, Johan Bosmans Tags: RESEARCH ARTICLE Source Type: research
Effects of experimental traumatic brain injury and impaired glutamate transport on cortical spreading depression - Hosseini-Zare MS, Gu F, Abdulla A, Powell S, Žiburkus J.
Cortical spreading depression (CSD) is associated with traumatic brain injury (TBI), stroke, migraines, and seizures. Typically, following TBIs and other insults, neuronal excitability in and around the area of the injury is affected, with reported increas...
Source: SafetyLit - May 12, 2017 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Estimating lifetime medical costs from censored claims data
In this study, we propose a survival‐adjusted estimator for estimating mean lifetime costs, which integrates the product of the survival function and the mean cost function over the lifetime horizon. The survival function is estimated by a new algorithm of rolling extrapolation, aided by external information of age‐ and sex‐matched referents simulated from national vital statistics. The mean cost function is estimated by a weighted average of mean expenditures of patients in a number of months prior to their death, of which the number could be determined by observed costs in their final months, and the weights depend...
Source: Health Economics - May 12, 2017 Category: Health Management Authors: Jing ‐Shiang Hwang, Tsuey‐Hwa Hu, Lukas Jyuhn‐Hsiarn Lee, Jung‐Der Wang Tags: RESEARCH ARTICLE Source Type: research
Understanding the mechanisms of recovery and/or compensation following injury - Hylin MJ, Kerr AL, Holden R.
Injury due to stroke and traumatic brain injury result in significant long-term effects upon behavioral functioning. One central question to rehabilitation research is whether the nature of behavioral improvement observed is due to recovery or the developm...
Source: SafetyLit - May 29, 2017 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
The Shock of Falling Among Older Americans
Publication date: Available online 9 June 2017 Source:The Journal of the Economics of Ageing Author(s): Inas R. Kelly Direct medical costs associated with falls have been shown to be $34 billion in 2013, an underestimate since full costs are not factored in. Using the 1998-2012 waves of the Health and Retirement Study and several econometric methods to address the endogeneity of falls, this study seeks to answer the question of how much worse physical and mental health outcomes are for individuals who fall compared to their steadier counterparts. Results across various specifications suggest that falling leads to lower ac...
Source: The Journal of the Economics of Ageing - June 10, 2017 Category: Health Management Source Type: research
Methods for estimating costs in patients with hyperlipidemia experiencing their first cardiovascular event in the United Kingdom.
CONCLUSIONS: Hospital costs represent the largest portion of acute and long-term costs in this population. Detailed costing using utilization data is feasible and representative of UK clinical practice, but is labor intensive. The availability of a standardized coding system in the UK drug costing data would greatly facilitate drug costing.
PMID: 28635339 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - June 22, 2017 Category: Health Management Tags: J Med Econ Source Type: research
Associations between Greenness, Impervious Surface Area, and Nighttime Lights on Biomarkers of Vascular Aging in Chennai, India
Conclusion:
Greenness, ISA, and NTL were associated with increased SBP, DBP, and cPP, and with reduced FMD, suggesting a possible additional EVA pathway for the relationship between urbanization and increased CVD prevalence in urban India. https://doi.org/10.1289/EHP541
Received: 20 May 2016
Revised: 03 January 2017
Accepted: 23 January 2017
Published: 02 August 2017
Address correspondence to K.J. Lane, Yale School of Forestry and Environmental Studies, 195 Prospect Street, New Haven, CT 06511 USA. Telephone: (781) 696-4537; Email: kevin.lane@yale.edu
Supplemental Material is available online (https://doi.org/10.1289...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Predictors for total hospital and cardiology cost claims among patients with atrial fibrillation initiating dabigatran or acenocoumarol in the Netherlands.
CONCLUSION: Dabigatran treatment was as a predictor for lower cardiology costs and lower total hospital care costs in AF patients that initiated oral anticoagulation.
PMID: 28766370 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - August 4, 2017 Category: Health Management Tags: J Med Econ Source Type: research
A comprehensive analysis of dispatching of traumatic brain injuries in the Fifth Period at the RAJAIE Hospital in Ghachsaran - Alidadi A, Zaboli R, Abedi R, Soltanizarandi MR.
INTRODUCTION: Increasing car accidents in young group and head-stroke mechanisms in developing countryis are the main cause of brain lesions and injuries related to trauma, so that traumatic severe brain lesions and injuries and uncontrollable hemorrhage a...
Source: SafetyLit - August 7, 2017 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
