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Total 383 results found since Jan 2013.

Trickle-Down Economics of Medical ImagingTrickle-Down Economics of Medical Imaging
There's a whole lot of imaging going on with ischemic stroke and its management with 'clot busters. Medscape Radiology
Source: Medscape Today Headlines - February 5, 2015 Category: Consumer Health News Tags: Radiology Expert Column Source Type: news

Overweight and obesity on the island of Ireland: an estimation of costs
Conclusions The costs are substantial, and urgent public health action is required in Ireland to address the problem of increasing prevalence of overweight and obesity, which if left unchecked will lead to unsustainable cost escalation within the health service and unacceptable societal costs.
Source: BMJ Open - March 16, 2015 Category: Journals (General) Authors: Dee, A., Callinan, A., Doherty, E., O'Neill, C., McVeigh, T., Sweeney, M. R., Staines, A., Kearns, K., Fitzgerald, S., Sharp, L., Kee, F., Hughes, J., Balanda, K., Perry, I. J. Tags: Open access, Epidemiology, Health economics Research Source Type: research

Lung cancer CT screening is cost-effective but implementation matters
Commentary on: Black WC, Gareen IF, Soneji SS, et al.; National Lung Screening Trial Research Team. Cost-effectiveness of CT screening in the National Lung Screening Trial. N Engl J Med 2014;37:1793–802. Context The National Lung Screening Trial (NLST) revealed a 20% reduction in lung cancer mortality from three annual low-dose CT screening scans compared with chest radiographs in high-risk individuals.1 Since up to 10 million individuals in the USA may qualify for annual CT screening, policymakers have legitimately questioned whether the benefits of lung cancer screening justify the potential high costs of large-sca...
Source: Evidence-Based Medicine - March 17, 2015 Category: Internal Medicine Authors: Goulart, B. Tags: Smoking and tobacco, Health policy, Epidemiologic studies, Stroke, Screening (oncology), Radiology, Clinical diagnostic tests, Radiology (diagnostics), Screening (epidemiology), Health economics, Health service research, Health education, Screening (publi Source Type: research

Environmental Barriers and Supports to Everyday Participation: A Qualitative Insider Perspective From People With Disabilities.
CONCLUSIONS: Participants with disabilities voiced the need to evaluate the impact of the environment on their participation at the immediate, community, and societal levels. The results have implications for assessing environmental facilitators and barriers to participation within rehabilitation and community settings, evaluating outcomes of environmental interventions, and effecting system and policy changes to target environmental barriers that may result in societal participation disparities versus opportunities. PMID: 25813890 [PubMed - as supplied by publisher]
Source: Medical Physics - April 1, 2015 Category: Physics Authors: Hammel J, Magasi S, Heinemann A, Gray DB, Stark S, Kisala P, Carlozzi NE, Tulsky D, Garcia SF, Hahn EA Tags: Arch Phys Med Rehabil Source Type: research

Exertional heat illness: emerging concepts and advances in prehospital care - Pryor RR, Roth RN, Suyama J, Hostler D.
Exertional heat illness is a classification of disease with clinical presentations that are not always diagnosed easily. Exertional heat stroke is a significant cause of death in competitive sports, and the increasing popularity of marathons races and ultr...
Source: SafetyLit: All (Unduplicated) - April 17, 2015 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

A systematic review of the efficacy of self-management programs for increasing physical activity in community-dwelling adults with acquired brain injury (ABI) - Jones TM, Dean CM, Hush JM, Dear BF, Titov N.
BACKGROUND: Individuals living with acquired brain injury, typically caused by stroke or trauma, are far less likely to achieve recommended levels of physical activity for optimal health and well-being. With a growing number of people living with chronic d...
Source: SafetyLit: All (Unduplicated) - May 7, 2015 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Heatstroke induces liver injury via IL-1β and HMGB1-induced pyroptosis - Geng Y, Ma Q, Liu YN, Peng N, Yuan FF, Li XG, Li M, Wu YS, Li BL, Song WB, Zhu W, Xu WW, Fan J, Su L.
BACKGROUND & AIMS: Liver injury is a common complication of heat stroke (HS), and often constitutes a direct cause for patient death. The cellular and molecular mechanism underlying HS-induced liver injury remains unclear. Recent evidence indicates that in...
Source: SafetyLit: All (Unduplicated) - May 11, 2015 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Areas of brain damage underlying increased reports of behavioral disinhibition - Knutson KM, Dal Monte O, Schintu S, Wassermann EM, Raymont V, Grafman J, Krueger F.
Disinhibition, the inability to inhibit inappropriate behavior, is seen in frontal-temporal degeneration, Alzheimer's disease, and stroke. Behavioral disinhibition leads to social and emotional impairments, including impulsive behavior and disregard for so...
Source: SafetyLit: All (Unduplicated) - May 15, 2015 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Implementing Guidelines: The Cost and Clinical Impact of Anticoagulants in the UK Atrial Fibrillation Population
Conclusions The clinical benefits of appropriate anticoagulation are widely recognised; however, full implementation can be difficult and costly. Therefore, the development of models can support the planning process by facilitating discussion among stakeholders on how best they can reach full implementation. The model is flexible and can be adapted to suit different payers.
Source: Applied Health Economics and Health Policy - June 15, 2015 Category: Health Management Source Type: research

Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery
Publication date: Available online 24 June 2015 Source:Pharmacology & Therapeutics Author(s): M. Zakkar , R. Ascione , A.F. James , G.D. Angelini , M.S. Suleiman Postoperative atrial fibrillation (POAF) is a common complication of cardiac surgery that occurs in up to 60% of patients. POAF is associated with increased risk of cardiovascular mortality, stroke and other arrhythmias that can impact on early and long term clinical outcomes and health economics. Many factors such as disease-induced cardiac remodelling, operative trauma, changes in atrial pressure and chemical stimulation and reflex sympathetic/ parasym...
Source: Pharmacology and Therapeutics - June 26, 2015 Category: Drugs & Pharmacology Source Type: research

Study finds obese people may struggle to reach a healthy weight
ConclusionThis research makes use of a general practice database providing just under 10 years of BMI observations for a large, nationally representative UK sample. It demonstrates that low proportions of people in the obese categories were able to achieve a normal BMI over a year of follow-up, and the common problem of weight cycling. However, there are points to consider when interpreting these results: The probability of obtaining a normal BMI over a year was very low: only 1 in 210 for men and 1 in 124 for women in the "simple obese" category of 30 to 35kg/m2, and much lower than that for the higher categor...
Source: NHS News Feed - July 20, 2015 Category: Consumer Health News Tags: Food/diet Obesity Source Type: news

Potential cost-savings may be considerable with management of hypertension according to updated US hypertension guidelines, but for women aged 35-44 years these benefits are unlikely
Commentary on: Moran AE, Odden MC, Thanataveerat A, et al. Cost-effectiveness of hypertension therapy according to 2014 guidelines. N Engl J Med 2015;372:447–55. Context The number of people with hypertension is anticipated to increase despite greater awareness of the condition as a risk factor for cardiovascular disease (CVD) and more options for treatment. Clinical guidelines are evidence-based recommendations used to inform clinician practice when treating an individual patient. Regular updates of guidelines are important to ensure their ongoing relevance. Moran and colleagues investigated the potential cost impli...
Source: Evidence-Based Medicine - July 24, 2015 Category: Internal Medicine Authors: Cadilhac, D. A., Kim, J. Tags: Health policy, Drugs: cardiovascular system, Stroke, Hypertension, Health economics, Health service research, Guidelines Economic analysis Source Type: research

Right care and high-value cardiology: doctors' responsibilities to the patient and the population
Significant advances in cardiovascular care, developed over the past three decades, are now routine treatment for people with heart disease—for example, primary angioplasty for acute ST elevation myocardial infarction is available to over 70% of the UK population, resynchronisation and defibrillator pacing devices are options for those with advanced heart failure, and drug therapies such as statins for secondary prevention have made significant impacts in reducing cardiovascular mortality in the past 50 years. Today, patients with cardiovascular disease can expect a better quality of life and greater longevity t...
Source: Postgraduate Medical Journal - August 24, 2015 Category: Journals (General) Authors: Malhotra, A., Apps, A., Saini, V., Gray, M. Tags: Patients, General practice / family medicine, Drugs: cardiovascular system, Stroke, Interventional cardiology, Ischaemic heart disease, Radiology, Clinical diagnostic tests, Cardiothoracic surgery, Vascular surgery, Epidemiology, Health economics Editor Source Type: research

Ezetimibe provides incremental reduction in risk for cardiovascular events and need for revascularisation following an acute coronary syndrome
Commentary on: Cannon CP, Blazing MA, Giugliano RP, et al., IMPROVE-IT Investigators. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med 2015;372:2387–97. Context Use of statin therapy to treat dyslipidemia in patients with established coronary artery disease is the standard of care worldwide. Given the negative results of a number of trials that tested the use of adjuvant lipid-lowering therapies against a statin background, there has been great scepticism about whether or not non-statin drugs provide incremental benefit.1–3 Ezetimibe inhibits the absorption of both dietary and bili...
Source: Evidence-Based Medicine - September 24, 2015 Category: Internal Medicine Authors: Toth, P. P. Tags: Health policy, Epidemiologic studies, Genetics, Immunology (including allergy), Vaccination / immunisation, Stroke, Diet, Ischaemic heart disease, Health economics, Health service research, Lipid disorders Therapeutics/Prevention Source Type: research

Economics of Team-based Care in Controlling Blood Pressure
Conclusions Team-based care to improve blood pressure control is cost effective based on evidence that 26 of 28 estimates of $/QALY gained from ten studies were below a conservative threshold of $50,000. This finding is salient to recent U.S. healthcare reforms and coordinated patient-centered care through formation of Accountable Care Organizations.
Source: American Journal of Preventive Medicine - October 15, 2015 Category: Global & Universal Source Type: research