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Total 277 results found since Jan 2013.

Prevention and follow-up in thromboembolic ischemic stroke: Do we need to think out of the box?
Stroke is one of the most debilitating thrombotic diseases, and world-wide it is estimated that by, 2030 23 million people will be affected. Except for the impact on the individual families, the world economy is also affected adversely. Although the medical treatment and knowledge of stroke are both increasing and well-researched, we still do not see a light in the tunnel. Currently various diagnostic tests are employed to determine the specific type of ischemic stroke as classified by the TOAST criteria.
Source: Thrombosis Research - November 4, 2015 Category: Hematology Authors: Albe C. Swanepoel, Etheresia Pretorius Tags: Review Article Source Type: research

Alterations in Aerobic Exercise Performance and Gait Economy Following High-Intensity Dynamic Stepping Training in Persons With Subacute Stroke
Conclusions: High-intensity stepping training may elicit significant improvements in O2submax, whereas changes in both peak capacity and economy better reflect gains in walking function. Providing high-intensity training to improve locomotor and aerobic exercise performance may increase the efficiency of rehabilitation sessions. Video Abstract available for more insights from the authors (see Supplemental Digital Content, http://links.lww.com/JNPT/A142 ).
Source: Journal of Neurologic Physical Therapy - September 24, 2016 Category: Physiotherapy Tags: Research Articles Source Type: research

Biomechanical mechanisms underlying exosuit-induced improvements in walking economy after stroke RESEARCH ARTICLE
This study elucidates the biomechanical mechanisms underlying exosuit-induced reductions in metabolic power. We evaluated the relationships between exosuit-induced changes in the body center of mass (COM) power generated by each limb, individual joint power and metabolic power. Compared with walking with an exosuit unpowered, exosuit assistance produced more symmetrical COM power generation during the critical period of the step-to-step transition (22.4±6.4% more symmetric). Changes in individual limb COM power were related to changes in paretic (R2=0.83, P=0.004) and non-paretic (R2=0.73, P=0.014) ankle power. Inte...
Source: Journal of Experimental Biology - March 7, 2018 Category: Biology Authors: Bae, J., Awad, L. N., Long, A., O'Donnell, K., Hendron, K., Holt, K. G., Ellis, T. D., Walsh, C. J. Tags: Comparative biomechanics of movement RESEARCH ARTICLE Source Type: research

The Interplay Between Walking Speed, Economy, and Stability After Stroke
CONCLUSIONS: People post-stroke appear to prefer walking speeds that are faster than their most stable speed but slower than their most economical speed. The preferred walking speed after stroke appears to balance stability and economy. To encourage faster and more economical walking, deficits in the stable control of the mediolateral motion of the pCoM may need to be addressed.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, http://links.lww.com/JNPT/A416).PMID:36867550 | DOI:10.1097/NPT.0000000000000431
Source: Physical Therapy - March 3, 2023 Category: Physiotherapy Authors: Louis N Awad Brian A Knarr Pawel Kudzia Thomas S Buchanan Source Type: research

Non-invasive brain stimulation to enhance stroke recovery – towards patient-tailored strategies
Stroke is the leading cause of serious long-term disability with growing impact on actual and future health economy. The resulting deficits of a stroke, e.g., of the upper extremity or language, have great impact on activities of daily life, social as well as professional.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: F.C. Hummel Source Type: research

Biomechanical mechanisms underlying exosuit-induced improvements in walking economy after stroke RESEARCH ARTICLE
This study elucidates the biomechanical mechanisms underlying exosuit-induced reductions in metabolic power. We evaluated the relationships between exosuit-induced changes in the body center of mass (COM) power generated by each limb, individual joint powers, and metabolic power. Compared to walking with an exosuit unpowered, exosuit assistance produced more symmetrical COM power generation during the critical period of the step-to-step transition (22.4±6.4% more symmetric). Changes in individual limb COM power were related to changes in paretic (R2= 0.83, P= 0.004) and nonparetic (R2= 0.73, P= 0.014) ankle power. I...
Source: Journal of Experimental Biology - January 18, 2018 Category: Biology Authors: Bae, J., Awad, L. N., Long, A., O'Donnell, K., Hendron, K., Holt, K. G., Ellis, T. D., Walsh, C. J. Tags: RESEARCH ARTICLE Source Type: research

Ditching masks at a stroke is too much too soon
Responding to the Prime Minister’s announcement end​ing rules requiring face coverings in enclosed public spaces, UNISON assistant general secretary Jon Richards said today (Monday): “This isn’t the time to throw caution to the wind, especially with infections on the rise. The economy is important, but so is public confidence. “These hasty changes will create a confusing cocktail of guidance. The public will be expected to know how to react to each and every situation they face. “Pressure is already building on ambulance and other NHS services, and that’s before safety measures are ditched. It’s just to...
Source: UNISON meat hygiene - July 5, 2021 Category: Food Science Authors: Anthony Barnes Tags: News Press release face coverings pandemic Source Type: news

Neuronal Death Mechanisms and Therapeutic Strategy in Ischemic Stroke
AbstractIschemic stroke caused by intracranial vascular occlusion has become increasingly prevalent with considerable mortality and disability, which gravely burdens the global economy. Current relatively effective clinical treatments are limited to intravenous alteplase and thrombectomy. Even so, patients still benefit little due to the short therapeutic window and the risk of ischemia/reperfusion injury. It is therefore urgent to figure out the neuronal death mechanisms following ischemic stroke in order to develop new neuroprotective strategies. Regarding the pathogenesis, multiple pathological events trigger the activa...
Source: Neuroscience Bulletin - May 5, 2022 Category: Neuroscience Source Type: research

The therapeutic benefits of intravenously administrated nanoparticles in stroke and age-related neurodegenerative diseases
Curr Pharm Des. 2022 Jun 8. doi: 10.2174/1381612828666220608093639. Online ahead of print.ABSTRACTThe mean global lifetime risk of neurological disorders such as stroke, Alzheimer's disease (AD), and Parkinson's disease (PD) has shown a large effect on economy and society.Researchersare stillstruggling to find effective drugs to treatneurological disordersand drug delivery through the blood-brain barrier (BBB) is a major challenge to be overcome. The BBB is a specialized multicellular barrier between the peripheral blood circulation and the neural tissue. Unique and selective features of the BBB allow it to tightly control...
Source: Current Pharmaceutical Design - June 9, 2022 Category: Drugs & Pharmacology Authors: Mehdi Farhoudi Saeed Sadigh-Eteghad Javad Mahmoudi Afsaneh Farjami Afsaneh Farjami Mohammad Mahmoudian Sara Salatin Source Type: research

A study on predicting the length of hospital stay for Chinese patients with ischemic stroke based on the XGBoost algorithm
The incidence of stroke is a challenge in China, as stroke imposes a heavy burden on families, national health services, social services, and the economy. The length of hospital stay (LOS) is an essential indi...
Source: BMC Medical Informatics and Decision Making - March 22, 2023 Category: Information Technology Authors: Rui Chen, Shengfa Zhang, Jie Li, Dongwei Guo, Weijun Zhang, Xiaoying Wang, Donghua Tian, Zhiyong Qu and Xiaohua Wang Tags: Research article Source Type: research