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Role of artificial intelligence and machine learning in the diagnosis of cerebrovascular disease
ConclusionThe implementation of AI and ML algorithms to supplement clinical practice has conferred a high degree of accuracy, efficiency, and expedited detection in the clinical and radiographic evaluation and management of ischemic and hemorrhagic strokes, AVMs, and aneurysms. Such algorithms have been explored for further purposes of prognostication for these conditions, with promising preliminary results. Further studies should evaluate the longitudinal implementation of such techniques into hospital networks and residency programs to supplement clinical practice, and the extent to which these techniques improve patient...
Source: Frontiers in Human Neuroscience - September 7, 2023 Category: Neuroscience Source Type: research

Edaravone Dexborneol Alleviates Neuroinflammation by Reducing Neuroglial Cell Proliferation and Suppresses Neuronal Apoptosis/Autophagy in Vascular Dementia Rats
In this study, we established the VD model of rats by bilateral carotid artery occlusion to explore the neuroprotective effect of EDB and its mechanism. Morris Water Maze test was applied to assess the cognitive function of rats. H&E and TUNEL staining were applied to observe the cellular structure of the hippocampus. Immunofluorescence labeling was used to observe the proliferation of astrocytes and microglia. ELISA was applied to examine the levels of TNF-α, IL-1β and IL-6, and RT-PCR was applied to examine their mRNA expression levels. Western blotting was applied to examine apoptosis-related proteins (Bax, Bcl-2,...
Source: Neurochemical Research - June 20, 2023 Category: Neuroscience Authors: Jiawei Zhang Yining Xiao Hongna Liu Lili Xu Xing Guo Yaran Gao Meixi Li Jing Xu Qianqian Qi Peiyuan Lv Source Type: research

Electric field simulations of transcranial direct current stimulation in children with perinatal stroke
DiscussionIndividualized patient-centered tDCS EF simulations are prudent for clinical trial planning and may provide insight into the efficacy of tDCS interventions in children with PS.
Source: Frontiers in Human Neuroscience - February 2, 2023 Category: Neuroscience Source Type: research

Small vessel disease burden predicts functional outcomes in patients with acute ischemic stroke using machine learning
CONCLUSIONS: Our results revealed that different SVD markers had distinct prognostic weights in AIS patients, and SVD burden alone may accurately predict the SVO-AIS patients' prognosis.PMID:36650639 | DOI:10.1111/cns.14071
Source: CNS Neuroscience and Therapeutics - January 17, 2023 Category: Neuroscience Authors: Xueyang Wang Jinhao Lyu Zhihua Meng Xiaoyan Wu Wen Chen Guohua Wang Qingliang Niu Xin Li Yitong Bian Dan Han Weiting Guo Shuai Yang Xiangbing Bian Yina Lan Liuxian Wang Qi Duan Tingyang Zhang Caohui Duan Chenglin Tian Ling Chen Xin Lou MR-STARS Investigat Source Type: research

Is Matrix Metalloproteinase-9 Associated with Post-Stroke Cognitive Impairment or Dementia?
CONCLUSIONS: MMP-9 level and MMP-9 rs3918242 polymorphism have an important role in the occurrence and development of post-stroke cognitive impairment or dementia (PSCID).PMID:36424752 | DOI:10.31083/j.jin2106160
Source: Journal of Integrative Neuroscience - November 25, 2022 Category: Neuroscience Authors: Jianhua Zhao Fangli Yang Xue Peng Qing Li Fan Wang Zhixiu Xu Ruiyan Cai Danxia Ji Jian Zhang Minghua Wang Qiong Li Sibei Ji Shaomin Li Source Type: research

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