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Neurocognitive Recovery of Sentence Processing in Aphasia.
Conclusions Sentence processing treatment results in improved comprehension and production of complex syntactic structures in chronic agrammatism and generalization to less complex, linguistically related structures in chronic agrammatism. Patients also show treatment-induced shifts toward normal-like online sentence processing routines (based on eye movement data) and changes in neural recruitment patterns (based on functional neuroimaging), with posttreatment activation of regions overlapping with those within sentence processing and dorsal attention networks engaged by neurotypical adults performing the same task. These...
Source: Journal of speech, language, and hearing research : JSLHR - November 21, 2019 Category: Speech-Language Pathology Authors: Thompson CK Tags: J Speech Lang Hear Res Source Type: research

Stacked Bidirectional Convolutional LSTMs for Deriving 3D Non-Contrast CT From Spatiotemporal 4D CT
The imaging workup in acute stroke can be simplified by deriving non-contrast CT (NCCT) from CT perfusion (CTP) images. This results in reduced workup time and radiation dose. To achieve this, we present a stacked bidirectional convolutional LSTM (C-LSTM) network to predict 3D volumes from 4D spatiotemporal data. Several parameterizations of the C-LSTM network were trained on a set of 17 CTP-NCCT pairs to learn to derive a NCCT from CTP and were subsequently quantitatively evaluated on a separate cohort of 16 cases. The results show that the C-LSTM network clearly outperforms the baseline and competitive convolutional neur...
Source: IEE Transactions on Medical Imaging - March 31, 2020 Category: Biomedical Engineering Source Type: research

T1AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex.
Abstract Abnormalities in thyroid hormones (TH) availability and/or metabolism have been hypothesized to contribute to Alzheimer's disease (AD) and to be a risk factor for stroke. Recently, 3-iodothyronamine (T1AM), an endogenous amine putatively derived from TH metabolism, gained interest for its ability to promote learning and memory in the mouse. Moreover, T1AM has been demonstrated to rescue the β-Amyloid dependent LTP impairment in the entorhinal cortex (EC), a brain area crucially involved in learning and memory and early affected during AD. In the present work, we have investigated the effect of T1AM on is...
Source: Neurobiology of Disease - January 19, 2021 Category: Neurology Authors: Tozzi F, Rutigliano G, Borsò M, Falcicchia C, Zucchi R, Origlia N Tags: Neurobiol Dis Source Type: research

HIV-positive people have higher incidence of coronary plaque
Coronary CT angiography (CCTA) shows that HIV-positive people have higher incidenc...Read more on AuntMinnie.comRelated Reading: CTA shows the effect of job stress on the heart Use of CTA, CT perfusion up -- but for the right reasons CCTA shows coronary plaque burden higher in people with HIV Machine learning helps find vessel occlusions on CTA CTA spots COVID-19 in stroke patients
Source: AuntMinnie.com Headlines - June 30, 2021 Category: Radiology Source Type: news

What are Some Risk Factors for Hypoxic-Ischemic Encephalopathy Outcomes?
Discussion “Neonatal encephalopathy, manifesting as altered responsiveness, seizures, apnea and abnormal muscle tone and reflexes, resulting from hypoxic-ischemic injury is termed hypoxic-ischemic encephalopathy (HIE).” Neonatal encephalopathy can be associated with other problems including stroke, hemorrhage, infection, pre-term brain injury and hypoglycemia as some examples. Sometimes more than one of these entities occurs simultaneously such as hypoglycemia and HIE. HIE can result in long-term neurological problems including motor, behavioral, and cognitive problems that can become apparent even years later....
Source: PediatricEducation.org - December 13, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Abstract No. 240 Automated outcome prediction in mechanical thrombectomy for acute large vessel ischemic stroke using 3D convolutional neural networks applied to CT angiography
Accurate prediction of clinical outcomes of acute large vessel occlusions (LVO) would lead to better patient selection and treatment planning for mechanical thrombectomy (MT). We developed a deep learning pipeline that predicts thrombectomy passes, immediate perfusion quality via the Thrombolysis in Cerebral Infarction (TICI) score and functional outcome via the 30-day modified Rankin Scale (mRS).
Source: Journal of Vascular and Interventional Radiology : JVIR - June 1, 2022 Category: Radiology Authors: L. Tran, S. Meng, P. Wang, I. Pan, T. Yi, R. Wang, Z. Jiao, H. Bai Source Type: research

The Great Contrast Shortage of 2022 —Lessons learnt in Australia
ConclusionOur findings demonstrate that the IBCM shortage crisis had a very significant impact on the delivery of healthcare. While V/Q scans could (partially) substitute for CTPA studies in suspected pulmonary emboli, there appeared to be no valid alternative for CTNA studies in stroke calls. The unexpected and critical shortage of IBCM forced healthcare professionals to conserve resources, prioritise indications, triage patients based on risk, explore alternate imaging strategies and prepare for similar events recurring in the future.
Source: Journal of Medical Imaging and Radiation Oncology - May 18, 2023 Category: Radiology Authors: Giles Kisby, James H Seow, Greg Schie, Constantine C Phatouros, Kay ‐Vin Lam, Tracey Muir, Sally Burrows, Paul M Parizel Tags: Medical Imaging —Original Article Source Type: research

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