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Total 258 results found since Jan 2013.

DWI Negative Stroke: Learning Points For Imaging In Acute Stroke (P1.037)
CONCLUSIONS: Clinical exam bears more weight than imaging in suspected brainstem infarcts. With the increasing use of DWI as the imaging of choice in acute stroke, DWI negative stroke must be considered in patients who present with classic brain stem infarcts with negative imaging to prevent delay in therapy as these patients may still be a candidate for thrombolysis.Disclosure: Dr. Nalleballe has nothing to disclose. Dr. JADEJA has nothing to disclose. Dr. Bollu has nothing to disclose. Dr. Onteddu has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Nalleballe, K., Jadeja, N., Bollu, P., Onteddu, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Contrast-enhanced ultrasound to predict the risk of microembolization during carotid artery stenting
Conclusion Contrast enhancement of the carotid plaque is strongly associated with post-procedural microembolization and for this reason it can be considered a reliable tool for an accurate selection of patients undergoing this endovascular treatment. However, the neurocognitive test scores performed in this study are not enough sensible to appreciate the impact of the neurological injury on the day life activities.
Source: La Radiologia Medica - March 25, 2015 Category: Radiology Source Type: research

Reducing delay to stroke thrombolysis--lessons learnt from the Stroke 90 Project
Conclusions The DtoCT pathway was successful in reducing delays to thrombolysis and should be implemented routinely. The call to door and CT to needle times were not improved by our interventions and further work is required to streamline these. Factors beyond the control of most hospitals may play a role in delaying treatment, but local changes can be implemented to mitigate this.
Source: Emergency Medicine Journal - January 20, 2015 Category: Emergency Medicine Authors: Kendall, J., Dutta, D., Brown, E. Tags: Stroke, Radiology, Clinical diagnostic tests, Resuscitation Original article Source Type: research

Immediately After A Stroke, Your Next Steps Are Crucial
By Shereen Lehman (Reuters Health) - Time is critical when someone has a stroke, but care can be delayed when victims, bystanders or even health workers don't recognize the emergency, a new study in the UK finds. Better public awareness of the signs of stroke and the importance of seeking immediate emergency care are needed, the authors say. Stroke signs include the sudden onset of various symptoms such as confusion, difficulty speaking, droopy face or slurred speech, weakness in a limb, numbness, being off-balance, visual loss or a really severe headache. "Getting to hospital quickly is...
Source: Science - The Huffington Post - December 12, 2014 Category: Science Source Type: news

Registration of challenging pre-clinical brain images
Publication date: 30 May 2013 Source:Journal of Neuroscience Methods, Volume 216, Issue 1 Author(s): William R. Crum , Michel Modo , Anthony C. Vernon , Gareth J. Barker , Steven C.R. Williams The size and complexity of brain imaging studies in pre-clinical populations are increasing, and automated image analysis pipelines are urgently required. Pre-clinical populations can be subjected to controlled interventions (e.g., targeted lesions), which significantly change the appearance of the brain obtained by imaging. Existing systems for registration (the systematic alignment of scans into a consistent anatomical coordinate...
Source: Journal of Neuroscience Methods - November 8, 2014 Category: Neuroscience Source Type: research

Accelerated three‐dimensional cine phase contrast imaging using randomly undersampled echo planar imaging with compressed sensing reconstruction
The aim of this study was to implement and evaluate an accelerated three‐dimensional (3D) cine phase contrast MRI sequence by combining a randomly sampled 3D k‐space acquisition sequence with an echo planar imaging (EPI) readout. An accelerated 3D cine phase contrast MRI sequence was implemented by combining EPI readout with randomly undersampled 3D k‐space data suitable for compressed sensing (CS) reconstruction. The undersampled data were then reconstructed using low‐dimensional structural self‐learning and thresholding (LOST). 3D phase contrast MRI was acquired in 11 healthy adults using an overall acceleratio...
Source: NMR in Biomedicine - October 16, 2014 Category: Radiology Authors: Tamer A. Basha, Mehmet Akçakaya, Beth Goddu, Sophie Berg, Reza Nezafat Tags: Research article Source Type: research

Visual scanning training for neglect after stroke with and without a computerized lane tracking dual task - van Kessel ME, Geurts AC, Brouwer WH, Fasotti L.
Neglect patients typically fail to explore the contralesional half-space. During visual scanning training, these patients learn to consciously pay attention to contralesional target stimuli. It has been suggested that combining scanning training with metho...
Source: SafetyLit: All (Unduplicated) - September 25, 2014 Category: Global & Universal Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Nurses’ fidelity to theory‐based core components when implementing Family Health Conversations – a qualitative inquiry
Background and aimA family systems nursing intervention, Family Health Conversation, has been developed in Sweden by adapting the Calgary Family Assessment and Intervention Models and the Illness Beliefs Model. The intervention has several theoretical assumptions, and one way translate the theory into practice is to identify core components. This may produce higher levels of fidelity to the intervention. Besides information about how to implement an intervention in accordance to how it was developed, evaluating whether it was actually implemented as intended is important. Accordingly, we describe the nurses’ fidelity to ...
Source: Scandinavian Journal of Caring Sciences - September 18, 2014 Category: Nursing Authors: Ulrika Östlund, Britt Bäckström, Viveca Lindh, Karin Sundin, Britt‐Inger Saveman Tags: Methods and Methodologies Source Type: research

Ctbrain machine learning predicts stroke thrombolysis result
Conclusions This proof-of-concept study shows that machine learning methods applied to acute stroke CT-scans potentially offers automation, and improved performance in SICH prediction following thrombolysis. Larger-scale cohorts, and incorporation of CT perfusion/angiography data, should be tested with such methods.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 9, 2014 Category: Neurosurgery Authors: Epton, S., Bentley, P., Ganesalingam, J., Dias, A., Mahady, K., Rinne, P., Sharma, P., Halse, O., Mehta, A., Rueckert, D. Tags: Abstracts Source Type: research

'Safe' stem cell therapy may help stroke recovery
Conclusion This study provides evidence that a new technique using a patient's own stem cells to aid the recovery from severe ischaemic stoke is feasible and appears to be safe. It was not designed to test whether the technique was better than doing nothing or better than other types of care or treatment. The authors are perfectly clear that this "proof-of-concept study was not designed with a control group or powered to be able to detect efficacy". This means we cannot be sure that the improvements seen in the five patients were caused by the stem cell treatment. They could have occurred anyway as part of the na...
Source: NHS News Feed - August 11, 2014 Category: Consumer Health News Tags: Genetics/stem cells Heart/lungs Source Type: news

Disassociation of verbal learning and hippocampal volume in type 2 diabetes and major depression
ConclusionsThe relationship between hippocampal volume and performance on the California Verbal Learning Test is decoupled in subjects with type 2 diabetes and major depression and this decoupling may contribute to poor verbal learning and memory performance in this study population. Copyright © 2014 John Wiley & Sons, Ltd.
Source: International Journal of Geriatric Psychiatry - June 12, 2014 Category: Geriatrics Authors: O. Ajilore, M. Lamar, J. Medina, K. Watari, V. Elderkin‐Thompson, A. Kumar Tags: Research Article Source Type: research

Cannabis linked to brain differences in the young
Conclusion This study found differences between young recreational cannabis users and non-users in the volume and structure of the nucleus accumbens and amygdala, which have a role in the brain’s reward system, pleasure response, emotion and decision making. However, as this was only a cross sectional study taking one-off brain scans of cannabis users and non-users, it cannot prove that cannabis use was the cause of any of the differences seen. It is not known whether cannabis use could have caused these changes in regular users.   Or conversely whether the cannabis users in this study had this brain structure to sta...
Source: NHS News Feed - April 16, 2014 Category: Consumer Health News Tags: Mental health Neurology Source Type: news

Do No Harm: Stories of Life, Death and Brain Surgery review
Patients see neurosurgeons as gods, but what is the reality? Henry Marsh has written a memoir of startling candourWe go to doctors for help and healing; we don't expect them to make us worse. Most people know the aphorism taught to medical students, attributed to the ancient Greek Hippocrates but timeless in its quiet sanity: "First, do no harm." But many medical treatments do cause harm: learning how to navigate the risks of drug therapies, as well as the catastrophic consequences of botched or inadvised surgical operations, is a big part of why training doctors takes so long. Even the simplest of therapies carries the ri...
Source: Guardian Unlimited Science - March 19, 2014 Category: Science Authors: Gavin Francis Tags: The Guardian Private healthcare Culture Society Reviews Books Neuroscience UK news Hospitals NHS Source Type: news

Predicting Future Brain Tissue Loss From White Matter Connectivity Disruption in Ischemic Stroke Clinical Sciences
Conclusions— ChaCo scores varied, but the most affected regions included those with sensorimotor, perception, learning, and memory functions. Correlations between baseline ChaCo and subsequent tissue loss suggest that the Network Modification Tool could be used to identify regions most susceptible to remote degeneration from acute infarcts.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Kuceyeski, A., Kamel, H., Navi, B. B., Raj, A., Iadecola, C. Tags: Computerized tomography and Magnetic Resonance Imaging, Pathology of Stroke Clinical Sciences Source Type: research