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Total 2908 results found since Jan 2013.

Assessment of ischemic penumbra in patients with hyperacute stroke using amide proton transfer (APT) chemical exchange saturation transfer (CEST) MRI
Chemical exchange saturation transfer (CEST)‐derived, pH‐weighted, amide proton transfer (APT) MRI has shown promise in animal studies for the prediction of infarction risk in ischemic tissue. Here, APT MRI was translated to patients with acute stroke (1–24 h post‐symptom onset), and assessments of APT contrast, perfusion, diffusion, disability and final infarct volume (23–92 days post‐stroke) are reported. Healthy volunteers (n = 5) and patients (n = 10) with acute onset of symptoms (0–4 h, n = 7; uncertain onset <24 h, n = 3) were scanned with diffusion‐ and perfusion‐weighted...
Source: NMR in Biomedicine - November 28, 2013 Category: Radiology Authors: Anna Tietze, Jakob Blicher, Irene Klærke Mikkelsen, Leif Østergaard, Megan K. Strother, Seth A. Smith, Manus J. Donahue Tags: Research article Source Type: research

Oxygen Extraction Fraction and Stroke Risk in Patients with Carotid Stenosis or Occlusion: A Systematic Review and Meta-Analysis BRAIN
CONCLUSIONS: Abnormal oxygen extraction fraction remains a powerful predictor of stroke in carotid stenosis or occlusion and is a valuable reference standard to compare and validate MR imaging–based measures of brain oxygen metabolism. However, there is a need for further evaluation of oxygen extraction fraction testing in patients with high-grade but asymptomatic carotid disease.
Source: American Journal of Neuroradiology - February 12, 2014 Category: Radiology Authors: Gupta, A., Baradaran, H., Schweitzer, A. D., Kamel, H., Pandya, A., Delgado, D., Wright, D., Hurtado-Rua, S., Wang, Y., Sanelli, P. C. Tags: BRAIN Source Type: research

Role of EPI-FLAIR in Patients with Acute Stroke: A Comparative Analysis with FLAIR FELLOWS' JOURNAL CLUB
CONCLUSIONS: In patients with acute stroke, EPI-FLAIR is feasible with comparable qualitative and quantitative results to conventional FLAIR and results in reduced acquisition time.
Source: American Journal of Neuroradiology - May 15, 2014 Category: Radiology Authors: Meshksar, A., Villablanca, J. P., Khan, R., Carmody, R., Coull, B., Nael, K. Tags: FELLOWS ' JOURNAL CLUB Source Type: research

CTA Collateral Status and Response to Recanalization in Patients with Acute Ischemic Stroke BRAIN
CONCLUSIONS: Patients with good or intermediate collaterals on CTA benefit from intra-arterial therapy, whereas patients with poor collaterals do not benefit from treatment.
Source: American Journal of Neuroradiology - May 15, 2014 Category: Radiology Authors: Nambiar, V., Sohn, S. I., Almekhlafi, M. A., Chang, H. W., Mishra, S., Qazi, E., Eesa, M., Demchuk, A. M., Goyal, M., Hill, M. D., Menon, B. K. Tags: BRAIN Source Type: research

Ultrafast in vivo diffusion imaging of stroke at 21.1 T by spatiotemporal encoding
ConclusionsConsideration of experiment duration, image quality, and mapped ADC values provided by spatiotemporally encoded demonstrates that this single‐shot acquisition is a method of choice for high‐throughput, ultrahigh‐field in vivo stroke quantification. Magn Reson Med, 2014. © 2014 Wiley Periodicals, Inc.
Source: Magnetic Resonance in Medicine - May 20, 2014 Category: Radiology Authors: Avigdor Leftin, Jens T. Rosenberg, Eddy Solomon, Fabian Calixto Bejarano, Samuel C. Grant, Lucio Frydman Tags: Full Paper Source Type: research

Free‐floating thrombus in stroke patients with nonstenotic internal carotid artery—An ultrasonographic study
ConclusionsInternal carotid artery FFT could be found in young stroke patients without identifiable arterial disease and could be resolved with antithrombotic treatment © 2014 Wiley Periodicals, Inc. J Clin Ultrasound, 2014
Source: Journal of Clinical Ultrasound - June 4, 2014 Category: Radiology Authors: Evguenia Vassileva, Marin Daskalov, Paraskeva Stamenova Tags: Research Article Source Type: research

Clinical and Angiographic Features and Stroke Types in Adult Moyamoya Disease FELLOWS' JOURNAL CLUB
CONCLUSIONS: In adult Moyamoya disease, major artery occlusion and collateral compensation occurred more often in the hemorrhagic than in the ischemic hemispheres. Thus, anterior cerebral artery occlusion with or without MCA occlusion and intracranial aneurysms may be the main contributing factors to hemorrhagic stroke in adult patients with Moyamoya disease.
Source: American Journal of Neuroradiology - June 11, 2014 Category: Radiology Authors: Jang, D.- K., Lee, K.- S., Rha, H. K., Huh, P.- W., Yang, J.- H., Park, I. S., Ahn, J.- G., Sung, J. H., Han, Y.- M. Tags: FELLOWS ' JOURNAL CLUB Source Type: research

Relative Filling Time Delay Based on CT Perfusion Source Imaging: A Simple Method to Predict Outcome in Acute Ischemic Stroke BRAIN
CONCLUSIONS: Relative filling time delay is a useful independent predictor of clinical outcome after ischemic stroke.
Source: American Journal of Neuroradiology - September 9, 2014 Category: Radiology Authors: Cao, W., Campbell, B. C. V., Dong, Q., Davis, S. M., Yan, B. Tags: BRAIN Source Type: research

Efficacy of systemic thrombolysis within 4.5 h from stroke symptom onset: a single-centre clinical and diffusion–perfusion 3T MRI study
Conclusion Treatment with IV rt-PA within 4.5 h of stroke onset preserves a significant amount of brain tissue from final infarction, and increases the possibility of early and late clinical improvement.
Source: La Radiologia Medica - October 1, 2014 Category: Radiology Source Type: research

Conscious Sedation versus General Anesthesia during Endovascular Acute Ischemic Stroke Treatment: A Systematic Review and Meta-Analysis EVIDENCE-BASED MEDICINE LEVEL 1
CONCLUSIONS: Patients with acute ischemic stroke undergoing intra-arterial therapy may have worse outcomes with general anesthesia compared with conscious sedation. However, the difference in stroke severity at the onset may confound the comparison in the available studies; thus, a randomized trial is necessary to confirm this association.
Source: American Journal of Neuroradiology - March 12, 2015 Category: Radiology Authors: Brinjikji, W., Murad, M. H., Rabinstein, A. A., Cloft, H. J., Lanzino, G., Kallmes, D. F. Tags: EVIDENCE-BASED MEDICINE LEVEL 1 Source Type: research

Percutaneous transluminal angioplasty and stenting for severe stenosis of the intracranial extradural internal carotid artery causing transient ischemic attack or minor stroke.
Authors: Ko JK, Choi CH, Cha SH, Choi BK, Cho WH, Kang TH, Sung SM, Cho HJ, Lee TH Abstract The purpose of this study is to assess the technical feasibility and clinical efficacy of percutaneous transluminal angioplasty and stenting (PTAS) for symptomatic stenosis of the intracranial extradural (petrous and cavernous) internal carotid artery (ICA).Review of medical records identified 26 consecutive patients who underwent PTAS using a balloon-expandable coronary stent (n = 15, 57.7%) or a Wingspan self-expandable stent (n = 11, 42.3%) for treatment of severe stenosis (>70%) involving the intracranial extr...
Source: Interventional Neuroradiology - June 13, 2015 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Brain effective connectivity during motor-imagery and execution following stroke and rehabilitation
This study expands our understanding of motor network involved during two different tasks, which are commonly used during rehabilitation following stroke. A clear understanding of the effective connectivity networks leads to a better treatment in helping stroke survivors regain motor ability.
Source: NeuroImage: Clinical - June 28, 2015 Category: Radiology Source Type: research

Carotid Intima‐Media Thickness is Inversely Related to Bone Density in Female but not in Male Patients with Acute Stroke
CONCLUSIONSThis study showed that carotid IMT/plaque thickness was inversely related to the BMD in female but not in male patients with acute ischemic stroke.
Source: Journal of Neuroimaging - September 1, 2015 Category: Radiology Authors: Shi Nae Kim, Hye Sun Lee, Hyo Suk Nam, Hwa Reung Lee, Jung Min Kim, Sang Won Han, Joong Hyun Park, Jong Sam Baik, Jeong Yeon Kim, Jae Hyeon Park Tags: Clinical Investigative Study Source Type: research

Frontoparietal white matter integrity predicts haptic performance in chronic stroke
This study demonstrates the importance of frontoparietal white matter in mediating haptic performance and specifically identifies that T-M1 and precuneus interhemispheric tracts may be appropriate targets for piloting rehabilitation interventions, such as noninvasive brain stimulation, when the goal is to improve poststroke haptic performance.
Source: NeuroImage: Clinical - November 13, 2015 Category: Radiology Source Type: research

Voxel-based lesion-symptom mapping of stroke lesions underlying somatosensory deficits
This study reveals that stroke lesions in the sensory fibers of the superior thalamocortical radiation and the parietal operculum are significantly associated with multiple exteroceptive and proprioceptive deficits in the arm and hand.
Source: NeuroImage: Clinical - December 12, 2015 Category: Radiology Source Type: research