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LIM kinase inhibitor T56-LIMKi protects mouse brain from photothrombotic stroke.
Conclusions: T56-LIMK2i may be considered as a promising anti-stroke agent. PMID: 33523710 [PubMed - as supplied by publisher]
Source: Brain Injury - February 3, 2021 Category: Neurology Tags: Brain Inj Source Type: research

An unusual case of Typhus group rickettsial infection presenting as cerebrovascular stroke.
Publication date: Available online 10 November 2015 Source:Pediatric Infectious Disease Author(s): C L Srinivasa Murthy, P Namitha, K Raghavendra, Naveen Kumar, Rajath Pejaver Rickettsial diseases are a group of infections caused by obligate intracellular gram negative bacilli and transmitted to man by arthropod vectors. They are prevalent in many parts in India and are characterized by microvasculitis, causing microinfarcts in various organs 1). Complications of rickettsial infection include pneumonias, renal failures and neurological involvement. Neurological complications such as meningitis and meningoencephaliti...
Source: Pediatric Infectious Disease - November 10, 2015 Category: Pediatrics Source Type: research

An unusual case of typhus group rickettsial infection presenting as cerebrovascular stroke
Publication date: Available online 10 November 2015 Source:Pediatric Infectious Disease Author(s): C.L. Srinivasa Murthy, P. Namitha, K. Raghavendra, Naveen Kumar, Rajath Pejaver Rickettsial diseases are a group of infections caused by obligate intracellular Gram-negative bacilli and transmitted to man by arthropod vectors. They are prevalent in many parts in India and are characterized by microvasculitis, causing microinfarcts in various organs. 1 Complications of rickettsial infection include pneumonias, renal failures, and neurological involvement. Neurological complications, such as meningitis and meningoencepha...
Source: Pediatric Infectious Disease - January 15, 2016 Category: Pediatrics Source Type: research

Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Idiopathic intracranial hypertension associated with iron-deficiency anaemia
A 12-year-old Nigerian girl presented to the Emergency Department with headache, dizziness and diplopia. She had a history of menorrhagia. Mild dyspnoea, tachycardia, left sixth cranial nerve palsy and papilloedema (figures 1 and 2) were noted. Body mass index was normal. Full blood count revealed haemoglobin of 4.8 g/dl. The red cells were hypochromic and mircocytic. A CT scan of the brain with venous contrast was normal. A lumbar puncture showed opening and closing pressures of 35 and 33.5 cm H2O, respectively. The diagnosis of idiopathic intracranial hypertension secondary to iron-deficiency anaemia was made. ...
Source: Archives of Disease in Childhood - May 9, 2013 Category: Pediatrics Authors: Forman, E. B., O'Byrne, J. J., Capra, L., McElnea, E., King, M. D. Tags: Miscellanea Source Type: research