TB of the radial neck: A typical presentation in an atypical location
This article describes the role of CT and MRI in evaluating a case of tuberculosis of the radial neck. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - December 17, 2016 Category: Pediatrics Source Type: research

Congenital dengue infection: Are we missing the diagnosis?
We present a case report of neonatal dengue with review of literature. A day 8 old newborn with maternally acquired dengue was admitted in our NICU and had an eventful course. This congenital dengue infection case gives us good learning experiences in a not so well understood entity. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 28, 2016 Category: Pediatrics Source Type: research

Applicability and Accuracy of Bacterial Meningitis Score in a resource-limited hospital setting in Thailand
In this study, BMS has 100% sensitivity (95%CI; 0.799-1) and 62.1% specificity (95%CI; 0.554-0.682). Positive predictive value(PPV) was 18.5% (95%CI;0.119-0.273) and negative predictive value(NPV) was 100% (95%CI; 0.967-1). BMS is a useful screening tool for early diagnosis of bacterial meningitis before cerebrospinal fluid culture result is known, especially when latex agglutination is not available. BMS is not recommended as a diagnostic confirmation tool because of its low specificity. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 19, 2016 Category: Pediatrics Source Type: research

Recurrent pneumonia and vaccine associated paralytic polio in a child with X-linked agammaglobulinemia
This report suggests the importance of evaluating patients with vaccine associated paralytic polio (VAPP) for immunodeficiency diseases. We describe a child with VAPP and recurrent pneumonias who had underlying X-linked agammaglobulinemia. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 17, 2016 Category: Pediatrics Source Type: research

TB of the radial neck: A typical presentation in an atypical location.
This article describes the role of CT and MRI in evaluating a case of tuberculosis of the radial neck. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 13, 2016 Category: Pediatrics Source Type: research

Congenital Dengue Infection: Are we missing the Diagnosis? Case report with review of literature
Publication date: Available online 13 September 2016 Source:Pediatric Infectious Disease Author(s): Ramani Ranjan, Kishore Kumar, Nandini Nagar (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 13, 2016 Category: Pediatrics Source Type: research

Neutrophil to Lymphocyte Ratio compared with C reactive protein to predict infection after major surgery in pediatric patients
Conclusions NLR value is not useful for diagnosis postoperative septic complications after pediatric major surgery. NLR value alone does not perform better compared with CRP value alone in predicting postoperative septic complications. The developmental differences in the host inflammatory response in children compared with adults may be the responsible of the different results obtained compared with studies reported in adults patients. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 12, 2016 Category: Pediatrics Source Type: research

Recurrent pneumonia and vaccine associated paralytic polio in a child with X linked agammaglobulinemia
This report suggests the importance of evaluating patients with vaccine associated paralytic polio (VAPP) for immunodeficiency diseases. We describe a child with VAPP and recurrent pneumonias who had underlying X linked agammaglobulinemia. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 12, 2016 Category: Pediatrics Source Type: research

Screening for Group B Streptococcal carriage in Antenatal cases in a tertiary care hospital
Publication date: Available online 12 September 2016 Source:Pediatric Infectious Disease Author(s): Adithi S. Shetty, Shekar Subbaiah, S. Anuradha, Prakash Kini, R. Kishore Kumar (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 12, 2016 Category: Pediatrics Source Type: research

Myocarditis With Pseudobulbar Palsy In A Six Year Old With Typhoid Fever
Publication date: Available online 12 September 2016 Source:Pediatric Infectious Disease Author(s): Sushant Mane, Sonali Singh, Swapnil Kumar, Dattatray Pandurang Shinde (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 12, 2016 Category: Pediatrics Source Type: research

Parainfluenza infection is associated with Henoch-Sch önlein purpura in children
Conclusions The presence of respiratory tract viruses was common in HSP children. PIV may be an important contributing factor in the pathogenesis of HSP. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 2, 2016 Category: Pediatrics Source Type: research

Disseminated bacille Calmette –Guérin disease in an infant with a novel biallelic mutation in interferon gamma receptor-1 gene
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): C.K. Indumathi, Bijayanti Mishra, A.S. Caroline Deswarte, Jacinta Bustamante (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - September 1, 2016 Category: Pediatrics Source Type: research

Status of introduction of pneumococcal conjugate vaccine in Pakistan
Publication date: April–June 2016 Source:Pediatric Infectious Disease, Volume 8, Issue 2 Author(s): Asad Ali, Sara Husain, Atif Riaz, Huma Khawar Streptococcus pneumoniae infection causes a wide spectrum of diseases ranging from acute otitis media to Invasive Pneumococcal Disease (IPD) presenting as pneumonia, meningitis, joint effusions, bacteraemia and septicaemia. Pakistan was the first country in the South Asian region to introduce PCV-10 within the routine immunisation program. Government of Pakistan, with support from Gavi, the Vaccine Alliance and other partners, introduced PCV-10 in phased manner, starting O...
Source: Pediatric Infectious Disease - August 16, 2016 Category: Pediatrics Source Type: research

Hospital-based surveillance for radiological pneumonia in children under 5 years of age in Uttar Pradesh and Bihar
Publication date: Available online 15 June 2016 Source:Pediatric Infectious Disease Author(s): Shally Awasthi, Jai Vir Singh, Neera Kohli, Monika Agarwal, Neelam Verma, Chandra Bhushan Kumar, Chittaranjan Roy, Kripa Nath Mishra, Pankaj Kumar Jain, Rajesh Yadav, Chandra Mani Pandey, Amit Kumar Srivastava Background and rationale Pneumonia is responsible for about 1.4 million deaths in children under five years of age, mostly in developing countries, including India. In India, Streptococcus pneumoniae (SP) and Haemophilus influenzae (HI) are the common bacterial etiologic agents of pneumonia, and often cause abnormal chest ...
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Laboratory based identification of pneumococcal infections: Current and future
This article summarizes newer methods and guidelines used for pneumococcal identification, serotyping and drug resistance testing. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Disseminated BCG disease with unusual manifestations
We report an interesting case of fever of unknown origin in an infant, closely mimicking hematological malignancy and Langerhans cell histiocytosis (LCH). Investigations revealed disseminated BCG disease with underlying immunodeficiency. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Pneumococcal disease and its prevention in India
Publication date: Available online 22 June 2016 Source:Pediatric Infectious Disease Author(s): Mathuram Santosham, Nirmal K. Ganguly (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Hemophagocytic lymphohistiocytosis associated with severe P. falciparum malaria – A case report
We report a case of 10-year-old female child with fever, hepatospenomegaly, pancytopenia, hyperferritinemia, hypertriglyceridemia and bone marrow hemophagocytosis, favoring the diagnosis of HLH. She required steroid administration for clinical remission. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Alliance for surveillance of invasive pneumococcal disease in India – The ASIP Study: Design and methodology
Publication date: Available online 22 June 2016 Source:Pediatric Infectious Disease Author(s): Anand Manoharan, Jyotsana Singh, Payal Deshpande Disease surveillance has been long recognized as the cornerstones for the public health decision making practices. In the regions of high childhood morbidity and mortality there is an unmet need of continued disease surveillance to identify the causes for menace. Pneumococcal surveillance in India has been heterogeneous with very few examples of attempts. Driven by the gap in the knowledge of nationwide epidemiological distribution of serotype and antibiogram pattern of Streptococ...
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Parainfluenza infection is associated with Henoch-Sch Önlein purpura in children
Conclusions The presence of respiratory tract viruses were common in HSP children.PIV may be an important contributing factor in the pathogenesis of HSP. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

18F-FDG PET/MRI for monitoring disseminated aspergillosis in a 16-year-old boy
We present a case of disseminated aspergillosis treated successfully with high-dose liposomal amphotericin B in a 16-year-old boy with primary immunodeficiency (autoimmune lymphoproliferative syndrome, ALPS). Sites of infection, including the brain, lung and multiple intra-abdominal organs, were studied using 18F-FDG and PET/MRI, which provided important morphological and functional information for monitoring the course of the disease. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Pediatric solitary cysticercosis in buccal mucosa
In this report we document a case of cysticercosis in 10 years child who sought treatment for an asymptomatic nodule in right buccal mucosa that has been clinically diagnosed as a submucosal retension cyst. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Pan India distribution of pneumococcal serotypes (PIDOPS) causing invasive pneumococcal disease and pneumonia in children between 6 weeks and 5 years and their antimicrobial resistance – Phase I
Publication date: Available online 2 July 2016 Source:Pediatric Infectious Disease Author(s): Govindan Vandana, Ahmed Ganaie Feroze, Nagaraj Geetha, Hussain Avid, K.L. Ravi Kumar Analysis of the published pneumococcal surveillance reports reveals variability and lack of long-term studies from India. The variability relates to case definition, characterization, surveillance, and laboratory methods. In the backdrop of scarcity of data, a multisite surveillance network study, PIDOPS Phase I, was launched in the year 2013 at 7 institutional and 51 sentinel sites. During the course of the study, novel molecular techniques were...
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Impact of antibiotic stewardship strategy on the outcome of non-critical hospitalized children with suspected viral infection
Conclusion Fever due to viral infections is very common even among non-critical hospitalized children. It is prudent to wait before starting antibiotics in such patients – it does not worsen the outcome. This study generates evidence for rational use of antimicrobials in paediatric practice. A protocol based ‘Antibiotic Stewardship Program’ can help in rationalizing antibiotic usage in selected group of patients. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - August 13, 2016 Category: Pediatrics Source Type: research

Community acquired MRSA infections —Three recent cases and an overview of CA MRSA infections
Publication date: January–March 2015 Source:Pediatric Infectious Disease, Volume 7, Issue 1 Author(s): Prakash Vaidya, Gauravi Pawar, Nisha Krishnamurthy Skin and soft tissue infections caused by Staphylococcus aureus are commonly encountered in pediatric practice. Staph infections acquired in the hospital setting are generally methicillin resistant. However these days, infections which are clearly “community acquired” are increasingly found to be due to methicillin resistant Staphylococcus—so called CA MRSA. Community-associated MRSA (CA-MRSA) refers to a MRSA infection with onset in the commu...
Source: Pediatric Infectious Disease - June 17, 2016 Category: Pediatrics Source Type: research

Serum zinc levels in children 6 months –12 years having tuberculosis
Conclusion Serum zinc levels are significantly affected in tuberculosis. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - June 17, 2016 Category: Pediatrics Source Type: research

Disseminated Bacille Calmette-Gu érin Disease in an Infant with a Novel bi-allelic Mutation in Interferon Gamma Receptor-1 Gene
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): C.K. Indumathi, Bijayanti Mishra, A.S. Caroline Deswarte, Jacinta Bustamante (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - June 17, 2016 Category: Pediatrics Source Type: research

Hospital Based Surveillance for Radiological Pneumonia in children under 5 years of age in Uttar Pradesh and Bihar
Publication date: Available online 15 June 2016 Source:Pediatric Infectious Disease Author(s): Shally Awasthi, Jai Vir Singh, Neera Kohli, Monica Agarwal, Neelam Verma, Chandra Bhushan Kumar, Chittaranjan Roy, Kripanath Mishra, Pankaj Kumar Jain, Rajesh Yadav, Chandra Mohan Pandey, Amit Kumar Srivastava Background and rationale Pneumonia is responsible for about 1.2 million deaths in children under five years of age, mostly in developing countries, including India. In India. Streptococcus pneumoniae (SP) and Hemophilus influenzae (HI) are the common bacterial etiologic agents of pneumonia, and often cause abn...
Source: Pediatric Infectious Disease - June 14, 2016 Category: Pediatrics Source Type: research

PCV 10 Introduction in National Immunization Program of Nepal
Publication date: Available online 3 June 2016 Source:Pediatric Infectious Disease Author(s): K.P. Paudel Nepal adopted immunization program as Expanded Program on Immunization in 1977 and is considered a successful program in Nepal for its role in the reduction of infant and under five mortality in the country. Pneumonia is a major killer of children and Streptococcus Pneumonia is the common cause of it. Based on the studies done in Nepal covering the existing serotypes National Committee on immunization practice recommended PCV 10 for its immunization program and it was rolled phase wise manner to all over the country...
Source: Pediatric Infectious Disease - June 3, 2016 Category: Pediatrics Source Type: research

Impact of Pneumococcal Conjugate Vaccines (PCV) on pneumonia, the forgotten killer of children
Publication date: Available online 3 June 2016 Source:Pediatric Infectious Disease Author(s): Nitin Shah (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - June 3, 2016 Category: Pediatrics Source Type: research

Crystal-induced nephrotoxicity associated with acyclovir use in paediatric patient
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Abin Chandrakumar, Ceriyac Jose Mundadan, Dilip Chandrasekhar, Sabin Tharappel Sojan, Sharanya Nair Drug-induced nephrotoxicity has evolved as one of the significant causes of renal failure in the contemporary setting accounting up to 20%. Acyclovir is an antiviral agent, which has the potential for precipitating transient crystal-induced nephrotoxicity, especially in elderly, euvolemic or renal patients when given as rapid intravenous bolus. The current case depicts evolution and management of transient nephropathy in a ...
Source: Pediatric Infectious Disease - May 26, 2016 Category: Pediatrics Source Type: research

Unusual presentation of enteric fever in an 11-year-old female child
We report a case of enteric fever that presented at the start as acute gastritis and then went on to develop acute pancreatitis, which is a rare complication of enteric fever, along with capillary leak syndrome in the acute phase mimicking dengue shock syndrome. This unusual presentation has not been reported in Indian or foreign literature. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - May 26, 2016 Category: Pediatrics Source Type: research

Pediatric gastrointestinal basidiobolomycosis
Publication date: Available online 4 April 2016 Source:Pediatric Infectious Disease Author(s): A. Eghbalkhah, M. Habibi, M. Lesanpezeshki, Sh. Shahinpour Basidiobolomycosis is a rare fungal disease caused by Basidiobolus ranarum, which is an environmental saprophyte. It is a chronic inflammatory disease that is generally restricted to the subcutaneous tissue and rarely involves the gastrointestinal tract. With the intent to spread awareness of this potentially life threatening and rare infection, we report a 4-year-old boy presenting with abdominal pain and fever with eventual diagnosis of gastrointestinal basidiobol...
Source: Pediatric Infectious Disease - May 26, 2016 Category: Pediatrics Source Type: research

Orbital entomophthoromycosis in a toddler – An unusual presentation/a case report
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Mourouguessine Vimal, Marie Therese Manipadam, Soosan Jacob Entomophthoromycosis is a rare fungal infection seldom occurring in humans. Only very few cases of entomophthoromycosis exclusively involving the orbit have been reported in the literature. We are reporting a case of entomophthoromycosis in a toddler who presented with swelling of the left orbit following trauma to the left eye. The nonspecific clinical signs and symptoms of the patient posed us diagnostic dilemma. Histopathological examination helped us to arrive ...
Source: Pediatric Infectious Disease - April 5, 2016 Category: Pediatrics Source Type: research

’Pediatric gastrointestinal Basidiobolomycosis’
Publication date: Available online 4 April 2016 Source:Pediatric Infectious Disease Author(s): A. Eghbalkhah, M. Habibi, M. Lesanpezeshki, Sh. Shahinpour Basidiobolomycosis is a rare fungal disease caused by basidiobolus ranarum which is an environmental saprophyte. It is a chronic inflammatory disease that is generally restricted to the subcutaneous tissue and rarely involves gastrointestinal tract. With the intent to spread the awareness of this potentially life threatening and rare infection, we report a 4 years old boy presenting with abdominal pain and fever with eventual diagnosis of gastrointestinal basidiobol...
Source: Pediatric Infectious Disease - April 4, 2016 Category: Pediatrics Source Type: research

Lab diagnosis of brucellosis
This article reviews the various culture methods, serological tests and newer diagnostic methods available in making a laboratory diagnosis of brucellosis along with their advantages and drawbacks. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Rotavirus infection markers in children with rotaviral gastroenteritis and their relation to disease severity
Conclusion Accordingly, we can conclude that rotaviral antigenemia and viremia were common in children with rotaviral diarrhea, however, the impact of rotavirus antigenemia/viremia on clinical manifestations of infection is unknown. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Cytomegalovirus Infection in Children after Bone Marrow Transplantation: Risk factors, Clinical aspects and Outcomes
Conclusions Antigenemia-guided pre-emptive strategy with ganciclovir was very affective and CMV reactivation tended not to affect the outcome in our study cohort. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Crystal Induced Nephrotoxicity Associated with Acyclovir Use in Paediatric Patient
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Abin Chandrakumar, Pretty G Tharakan, Bittu Thomas, Anu Albert, Teena Jacob Drug induced nephrotoxicity has evolved as one of the significant causes of renal failure in the contemporary setting accounting up to 20%. Acyclovir is an antiviral agent which has potential for precipitating transient crystal induced nephrotoxicity especially in elderly, euvolemic or renal patients when given as rapid intravenous bolus. The current case depicts evolution and management of transient nephropathy in a paediatric patient treated wit...
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Unusual presentation of enteric fever in 11 year old female child
We report a case of enteric fever which presented to start with as acute gastritis and then went on to develop acute pancreatitis which is a rare complication of enteric fever; along with capillary leak syndrome in the acute phase mimicking dengue shock syndrome. This unusual presentation has not been reported in Indian or foreign literature. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Orbital entomophthoromycosis in a toddler–an unusual presentation/a case report
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Mourouguessine Vimal, Marie Therese Manipadam, Soosan Jacob Entomophthoromycosis is a rare fungal infection seldom occurring in humans. Only very few cases of Entomophthoromycosis exclusively involving the orbit have been reported in the literature. We are reporting a case of Entomophthoromycosis in a toddler who presented with swelling of the left orbit following trauma to the left eye. The nonspecific clinical signs and symptoms of the patient posed us diagnostic dilemma. Histopathological examination helped us to arrive ...
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Disseminated Bacille Calmette-Guérin Disease in an Infant with a Novel bi-allelic Mutation in Interferon Gamma Receptor-1 Gene
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): C.K. Indumathi, Bijayanti Mishra, A.S. Caroline Deswarte, Jacinta Bustamante (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Fixed dose combination of Anti-tubercular drugs: Time to reformulate
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Sumit Mehndiratta (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Rapid diagnosis of childhood TB: Can we meet pediatric TB requirements?
Publication date: Available online 3 March 2016 Source:Pediatric Infectious Disease Author(s): Chaitali Nikam, Asawari Chavan, Swapna Naik, Archana Khillari, Lancelot Pinto, Anjali Shetty, Camilla Rodrigues (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 5, 2016 Category: Pediatrics Source Type: research

A Case Report of Bartonella Endocarditis with Pancytopenia
Publication date: Available online 2 March 2016 Source:Pediatric Infectious Disease Author(s): Heather Riebel, Michael Hainstock, Jane Atkins A nine year old male with history of complex congenital heart disease presented with intermittent fevers and chills of three month duration along with pancytopenia. Given a high suspicion for endocarditis despite negative blood cultures, a literature search for culture negative endocarditis yielded the possibility of less common organisms, including zoonotic agents. There were only isolated case reports of Bartonella causing pancytopenia. Further testing revealed positive Barton...
Source: Pediatric Infectious Disease - March 3, 2016 Category: Pediatrics Source Type: research

Nodular Lymphangitis Caused by Mycobacterium marinum
Publication date: Available online 21 February 2016 Source:Pediatric Infectious Disease Author(s): Mazen Saleh, Mark Saleh A five year old boy with an infection in the area of the external malleolus of the right foot was presented to a local walk-in clinic for which amoxicillin was prescribed. Upon completion of the course of the antibiotic the inflammation in the primary area of the infection subsided but the multiple sites of nodular lymphangitis in the surrounding area persisted. Examination of those sites lead to the identification of Mycobacterium marinum as the cause of the co-infection. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - February 22, 2016 Category: Pediatrics Source Type: research

The relevance of the serum levels of C-reactive protein and creatine kinase-MB to the severity of hand-foot-and-mouth disease patients in China: A meta-analysis
Conclusions The result of these analyses indicated that the CRP and CK-MB levels are correlated with HFMD severity. Thus, these frequently used and accessible measures may aid clinicians in effectively diagnosing, treating, and predicting the prognosis of children with HFMD. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - February 21, 2016 Category: Pediatrics Source Type: research

Rickettsial diseases in India – A long way ahead…
Publication date: Available online 2 February 2016 Source:Pediatric Infectious Disease Author(s): Narendra Rathi (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - February 11, 2016 Category: Pediatrics Source Type: research

The Relevance of Serum C-reactive Protein and Creatine Kinase-MB Levels to the Severity of Hand-Foot-and-Mouth Disease Patients in China: A Systematic Review and Meta-analysis
Conclusions The result of these analyses indicated that the CRP and CK-MB levels are correlated with HFMD severity. Thus, these frequently used and accessible measures may aid clinicians in effectively diagnosing, treating, and predicting the prognosis of children with HFMD. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - February 10, 2016 Category: Pediatrics Source Type: research

Neurological manifestations of Rickettsial infections in children
Conclusions Myriads of neurological manifestations were seen with varying range of severity. Pediatricians should be aware of neurological manifestations seen in Rickettsial infections and should have high index of suspicion for Rickettsial diseases in febrile patients having neurological features specially in endemic areas. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - February 3, 2016 Category: Pediatrics Source Type: research