• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Estimating minimally important differences for the PROMIS pain interference scales: results from 3 randomized clinical trials
Minimally important difference (MID) refers to the smallest meaningful difference that carries implications for patient care. Minimally important differences are necessary to help interpret patient-reported pain outcomes in research and clinical practice. The PROMIS pain interference scales were validated across diverse samples; however, more information about their MIDs could improve their interpretability. The purpose of this study was to estimate MIDs for 4 fixed-length PROMIS pain interference scales, including the 6-item Pain Short Form and the 4-, 6-, and 8-item pain interference scales used in the PROMIS profile ins...
Source: Pain - March 27, 2018 Category: Anesthesiology Tags: Research Paper Source Type: research

Management of antiplatelet therapy in patients undergoing elective invasive procedures. Proposals from the French Working Group on perioperative haemostasis (GIHP) and the French Study Group on thrombosis and haemostasis (GFHT). In collaboration with the French Society for Anaesthesia and Intensive Care Medicine (SFAR)
Publication date: Available online 5 January 2018 Source:Anaesthesia Critical Care & Pain Medicine Author(s): Anne Godier, Pierre Fontana, Serge Motte, Annick Steib, Fanny Bonhomme, Sylvie Schlumberger, Thomas Lecompte, Nadia Rosencher, Sophie Susen, André Vincentelli, Yves Gruel, Pierre Albaladejo, Jean-Philippe Collet The French Working Group on Perioperative Haemostasis (GIHP) and the French Study Group on Haemostasis and Thrombosis (GFHT) in collaboration with the French Society for Anaesthesia and Intensive Care Medicine (SFAR) drafted up-to-date proposals for the management of antiplatelet therapy in patien...
Source: Anaesthesia, Critical Care and Pain Medicine - March 3, 2018 Category: Anesthesiology Source Type: research

Deficient Pain Modulation in Patients with Chronic Hemiplegic Shoulder Pain
ConclusionsThe results suggest that HSP is associated with a lack of pain adaptation, characteristic not only of the painful shoulder but also of the affected side. Although we cannot determine whether lack of pain adaptation precedes the HSP or results from it, interventions that enhance descending pain inhibition may improve management and prevent HSP chronification.
Source: Pain Practice - January 11, 2018 Category: Anesthesiology Authors: Yafit Kashi, Motti Ratmansky, Ruth Defrin Tags: Original Article Source Type: research

Management Of Antiplatelet Therapy In Patients Undergoing Elective Invasive Procedures Proposals From The French Working Group On Perioperative Hemostasis (Gihp) And The French Study Group On Thrombosis And Hemostasis (Gfht) In Collaboration With The French Society For Anesthesia And Intensive Care (Sfar)
Publication date: Available online 5 January 2018 Source:Anaesthesia Critical Care & Pain Medicine Author(s): Anne Godier, Pierre Fontana, Serge Motte, Annick Steib, Fanny Bonhomme, Sylvie Schlumberger, Thomas Lecompte, Nadia Rosencher, Sophie Susen, André Vincentelli, Yves Gruel, Pierre Albaladejo, Jean-Philippe Collet The French Working Group on Perioperative Hemostasis (GIHP) and the French Study Group on Hemostasis and Thrombosis (GFHT) in collaboration with the French Society for Anesthesia and Intensive Care (SFAR) drafted up-to-date proposals for the management of antiplatelet therapy in patients undergoin...
Source: Anaesthesia, Critical Care and Pain Medicine - January 6, 2018 Category: Anesthesiology Source Type: research

Deficient pain modulation in patients with a chronic hemiplegic shoulder pain
ConclusionsThe results suggest that HSP is associated with a lack of pain adaptation, characteristic not only of the painful shoulder but also of the affected side. Although we cannot determine whether lack of pain adaptation precede the HSP or result from it, interventions that enhance descending pain inhibition may improve management and prevent HSP chronification.This article is protected by copyright. All rights reserved.
Source: Pain Practice - November 1, 2017 Category: Anesthesiology Authors: Yafit Kashi, Motti Ratmansky, Ruth Defrin Tags: Original Article Source Type: research

Dynamic Arterial Elastance Obtained Using Arterial Signal Does Not Predict An Increase In Arterial Pressure After A Volume Expansion in the Operating Room
Conclusion In the present study performed in the OR and in hypotensive patients, Eadyn obtained using arterial signal was unable to predict an increase in MAP after volume expansion.
Source: Anaesthesia, Critical Care and Pain Medicine - July 8, 2017 Category: Anesthesiology Source Type: research

Targeted temperature management in the ICU: guidelines from a French expert panel
We present herein recommendations for the use of TTM in adult and paediatric critically ill patients developed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method. These guidelines were conducted by a group of experts from the French Intensive Care Society (Société de Réanimation de Langue Française [SRLF]) and the French Society of Anesthesia and Intensive Care Medicine (Société Francaise d’Anesthésie Réanimation [SFAR]) with the participation of the French Emergency Medicine Association (Société Française de Médecine d’Urgence [SFMU]), the French Group for Pediatric...
Source: Anaesthesia, Critical Care and Pain Medicine - July 6, 2017 Category: Anesthesiology Source Type: research

Dexmedetomidine and general anesthesia: a narrative literature review of its major indications for use in adults undergoing non-cardiac surgery.
CONCLUSIONS: The properties of dexmedetomidine lead to its use for elective indications such as awake fiberoptic intubation and neurosurgical anesthesia. New topics are under debate. These subjects must be studied thoroughly because of their implication in the patients' surgical course. These advantages must be weighed against the major drawback of dexmedetomidine administration which is the potential for hemodynamic abnormalities. PMID: 28643999 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - June 25, 2017 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Targeting brain-derived neurotrophic factor in the medial thalamus for the treatment of central poststroke pain in a rodent model
Abstract: Approximately 7% to 10% of patients develop a chronic pain syndrome after stroke. This chronic pain condition is called central poststroke pain (CPSP). Recent studies have observed an abnormal increase in the secretion of brain-derived neurotrophic factor (BDNF) in spinal cord tissue after spinal cord injury. An animal model of CPSP was established by an intrathalamus injection of collagenase. Mechanical and thermal allodynia was induced after lesions of the thalamic ventral basal complex in rats. Four weeks after the injection, the number of neurons decreased, the number of astrocytes, microglia, and P2X4 recept...
Source: Pain - June 22, 2017 Category: Anesthesiology Tags: Research Paper Source Type: research

Impact of Pain on Incident Risk of Disability in Elderly Japanese Cause-specific Analysis
This study aimed to investigate the association of pain severity with subsequent functional disability due to all causes as well as stroke, dementia, and joint disease/fracture.Methods The authors conducted a prospective cohort study of 13,702 Japanese individuals aged 65 yr or older. Information regarding pain severity during the previous 4 weeks and other lifestyle factors was collectedvia questionnaire in 2006. Data on the incidence of functional disability were retrieved from the Long-term Care Insurance database. Cox proportional hazards regression analysis was used to estimate the multivariate-adjusted hazard ratios ...
Source: Anesthesiology - March 14, 2017 Category: Anesthesiology Source Type: research

In Vogue: Ketamine for Neuroprotection in Acute Neurologic Injury.
Abstract Neurologic deterioration following acute injury to the central nervous system may be amenable to pharmacologic intervention, although, to date, no such therapy exists. Ketamine is an anesthetic and analgesic emerging as a novel therapy for a number of clinical entities in recent years, including refractory pain, depression, and drug-induced hyperalgesia due to newly discovered mechanisms of action and new application of its known pharmacodynamics. In this focused review, the evidence for ketamine as a neuroprotective agent in stroke, neurotrauma, subarachnoid hemorrhage, and status epilepticus is highligh...
Source: Anesthesia and Analgesia - January 9, 2017 Category: Anesthesiology Authors: Bell JD Tags: Anesth Analg Source Type: research

Delirium after cardiac surgery: A pilot study from a single tertiary referral center.
CONCLUSIONS: Patients who developed delirium had systemic disease in the form of hypertension and cerebrovascular disease. Delirium was seen in patients who had higher postoperative pain scores, longer ICU stay, and NIV use. This study can be used to develop a predictive tool for diagnosing postcardiac surgical delirium. PMID: 28074801 [PubMed - in process]
Source: Annals of Cardiac Anaesthesia - December 31, 2016 Category: Anesthesiology Authors: Kumar AK, Jayant A, Arya VK, Magoon R, Sharma R Tags: Ann Card Anaesth Source Type: research

Animal models for central poststroke pain: a critical comprehensive review
Abstract: Central poststroke pain (CPSP) is a severe type of neuropathic pain that can develop after stroke and is difficult to treat. Research into its underlying mechanisms and treatment options could benefit from a valid CPSP animal model. Nine different CPSP animal models have been published, but there are relatively few reports on successful reproductions of these models and so far only little advances in the understanding or the management of CPSP have been made relying on these models. In general, the construct validity (similarity in underlying mechanisms) of these CPSP animal models is relatively high, although th...
Source: Pain - December 30, 2016 Category: Anesthesiology Tags: Comprehensive Review Source Type: research

Mechanical pinprick pain in patients with unilateral spatial neglect: The influence of space representation on the perception of nociceptive stimuli
ConclusionThese findings uphold the notion that the perception of nociceptive stimuli is modulated by the relative position of the hands in space, but raise questions about the conditions under which these effects may arise. SignificanceWe show that deficits in space representation can influence the processing of mechanical pinprick stimuli. Our results raise several questions on the mechanisms underlying these effects, which are relevant for the clinical practice.
Source: European Journal of Pain - December 14, 2016 Category: Anesthesiology Authors: V. Vizzari, S. Barba, P. Gindri, S. Duca, D. Giobbe, P. Cerrato, G. Geminiani, D.M. Torta Tags: Original Article Source Type: research

The Genetics of Pain
This article aims to review some human pain conditions, both common and rare, and their possible association with ion channels, receptors and the genes involved. Current and ongoing research evidence of the involvement of multiple cellular and molecular pathways in pain, advances in gene therapy and new medications are mentioned, as well as their limitations due to the complexity of pain.
Source: Current Anesthesiology Reports - November 16, 2016 Category: Anesthesiology Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12