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Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe
Background As mortality from coronavirus disease 2019 (COVID-19) is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age-/gender-adjusted data from European cohort studies with the aim to identify populations that could potentially benefit from booster vaccinations. Methods We performed a systematic literature review and meta-analysis to investigate the role of underlying medical conditions as prognostic factors for adverse outcomes due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including death, hospitalisation, intensive c...
Source: European Respiratory Review - November 2, 2022 Category: Respiratory Medicine Authors: Vardavas, C. I., Mathioudakis, A. G., Nikitara, K., Stamatelopoulos, K., Georgiopoulos, G., Phalkey, R., Leonardi-Bee, J., Fernandez, E., Carnicer-Pont, D., Vestbo, J., Semenza, J. C., Deogan, C., Suk, J. E., Kramarz, P., Lamb, F., Penttinen, P. Tags: Respiratory infections and tuberculosis Reviews Source Type: research

COVID-19, Overdoses Made 2021 The Deadliest Year in U.S. History
2021 was the deadliest year in U.S. history, and new data and research are offering more insights into how it got that bad. The main reason for the increase in deaths? COVID-19, said Robert Anderson, who oversees the Centers for Disease Control and Prevention’s work on death statistics. The agency this month quietly updated its provisional death tally. It showed there were 3.465 million deaths last year, or about 80,000 more than 2020’s record-setting total. Early last year, some experts were optimistic that 2021 would not be as bad as the first year of the pandemic — partly because effective COVID-19 vac...
Source: TIME: Health - April 12, 2022 Category: Consumer Health News Authors: MIKE STOBBE / AP Tags: Uncategorized COVID-19 healthscienceclimate wire Source Type: news

COVID-19 postacute care major organ damage: a systematic review
Conclusions and implications of key findings Postacute COVID-19 major organ damage is common and likely higher than controls. However, there is substantial uncertainty. More consistent reporting of clinical outcomes and pre-COVID health status along with careful selection of control groups are needed to address evidence gaps. PROSPERO registration number CRD42020204788.
Source: BMJ Open - August 24, 2022 Category: General Medicine Authors: Greer, N., Bart, B., Billington, C. J., Diem, S. J., Ensrud, K. E., Kaka, A., Klein, M., Melzer, A. C., Reule, S., Shaukat, A., Sheets, K., Starks, J., Vardeny, O., McKenzie, L., Stroebel, B., Macdonald, R., Sowerby, K., Duan-Porter, W., Wilt, T. J. Tags: Open access, Infectious diseases, COVID-19 Source Type: research

Professor elected to National Academy of Medicine
Dr. Arleen Brown, professor of medicine in the division of general internal medicine and health services research at the David Geffen School of Medicine at UCLA, has been elected to the National Academy of Medicine.Brown, who is also co-director of the UCLA Clinical and Translational Science Institute and chief of the division of general internal medicine and health services research at Olive View-UCLA Medical Center, was one of 100 new members announced today during the academy ’s annual meeting in Washington, D.C.She was recognized as “a pioneer in understanding how community, policy, health system, and individual fa...
Source: UCLA Newsroom: Health Sciences - October 18, 2022 Category: Universities & Medical Training Source Type: news

Neurological Complications and Consequences of the Novel Coronavirus COVID-19 Infection in Elderly and Senile Patients (Literature Review)
AbstractBased on available publications, the article systematizes information about some forms of lesions of the central nervous system (CNS), their pathogenesis and clinical manifestations in the case of COVID-19. The risk factors, mechanisms of development, diagnostic approach, and the age characteristics of patients with neurological complications of COVID-19 are discussed. The specific mechanisms of the neuroinvasiveness and neurovirulence of the SARS-CoV-2 virus, regardless of the age of patients and the presence of risk factors, lead to systemic damage to the endothelium of small-caliber vessels, generalized thrombov...
Source: Advances in Gerontology - December 1, 2022 Category: Geriatrics Source Type: research

Safety of COVID-19 Vaccines among Patients with Type 2 Diabetes Mellitus: Real-World Data Analysis
CONCLUSION: Careful monitoring of severe AEs in patients with T2DM may be necessary, especially for those related to thrombotic events and neurological dysfunctions after COVID-19 vaccination.PMID:36872064 | DOI:10.4093/dmj.2022.0129
Source: Diabetes and Metabolism Journal - March 5, 2023 Category: Endocrinology Authors: Hye Jun Kim Sang Jun Lee Soonok Sa Jung Ho Bae Gyuseon Song Chae Won Lee Ju Hee Kim Sung Ryul Shim Myunghee Hong Hyun Wook Han Source Type: research

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