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Lipoprotein(a) and Cardiovascular Diseases 　- Revisited.
Lipoprotein(a) and Cardiovascular Diseases　- Revisited. Circ J. 2020 Apr 24;: Authors: Jang AY, Han SH, Sohn IS, Oh PC, Koh KK Abstract Two decades ago, it was recognized that lipoprotein(a) (Lp(a)) concentrations were elevated in patients with cardiovascular disease (CVD). However, the importance of Lp(a) was not strongly established due to a lack of both Lp(a)-lowering therapy and evidence that reducing Lp(a) levels improves CVD risk. Recent advances in clinical and genetic research have revealed the crucial role of Lp(a) in the pathogenesis of CVD. Mendelian randomization studies have shown that ...
Source: Circulation Journal - April 23, 2020 Category: Cardiology Authors: Jang AY, Han SH, Sohn IS, Oh PC, Koh KK Tags: Circ J Source Type: research

Multimorbidity in Patients With Acute Coronary Syndrome Is Associated With Greater Mortality, Higher Readmission Rates, and Increased Length of Stay: A Systematic Review.
CONCLUSIONS: Multimorbid patients with ACS are at a greater risk for worse outcomes than their nonmultimorbid counterparts. Lack of consistent measurement makes interpretation of the impact of multimorbidity challenging and emphasizes the need for more research on multimorbidity's effects on postdischarge healthcare utilization. PMID: 32925234 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Nursing - September 8, 2020 Category: Nursing Authors: Breen K, Finnegan L, Vuckovic K, Fink A, Rosamond W, DeVon HA Tags: J Cardiovasc Nurs Source Type: research

Cardiovascular and renal morbidity in Takayasu arteritis: a population ‐based retrospective cohort study from UK
ConclusionCardiovascular morbidity was increased in patients with TA attending primary care services in the UK. Treatment with statins and anti ‐platelets in these patients was suboptimal.
Source: Arthritis and Rheumatology - September 22, 2020 Category: Rheumatology Authors: Ruchika Goel, Joht Singh Chandan, Rasiah Thayakaran, Nicola J Adderley, Krishnarajah Nirantharakumar, Lorraine Harper Tags: FULL LENGTH Source Type: research

Multimorbidity in Patients With Acute Coronary Syndrome Is Associated With Greater Mortality, Higher Readmission Rates, and Increased Length of Stay: A Systematic Review
Conclusions Multimorbid patients with ACS are at a greater risk for worse outcomes than their nonmultimorbid counterparts. Lack of consistent measurement makes interpretation of the impact of multimorbidity challenging and emphasizes the need for more research on multimorbidity's effects on postdischarge healthcare utilization.
Source: Journal of Cardiovascular Nursing - October 21, 2020 Category: Nursing Tags: Feature Article/Online Only Source Type: research

Prevalence of Guideline-Directed Medical Therapy for Cardiovascular Disease Among Baltimore City Adults in the Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) Study
ConclusionsAmong an urban-dwelling population of adults, the use of secondary prevention of CVD was low, with lower aspirin and combination GDMT for Black participants with CAD. Efforts to improve GDMT use at the patient and provider levels may be needed to improve morbidity and mortality and reduce disparities in CVD.
Source: Journal of Racial and Ethnic Health Disparities - February 16, 2021 Category: International Medicine & Public Health Source Type: research

Cardiovascular and Renal Morbidity in Takayasu Arteritis: A Population ‐Based Retrospective Cohort Study From the United Kingdom
ConclusionCardiovascular morbidity was increased among patients with TAK receiving primary care services in the UK. Treatment with statins and antiplatelet agents in these patients was suboptimal.
Source: Arthritis and Rheumatology - February 27, 2021 Category: Rheumatology Authors: Ruchika Goel, Joht Singh Chandan, Rasiah Thayakaran, Nicola J. Adderley, Krishnarajah Nirantharakumar, Lorraine Harper Tags: Full Length Source Type: research

Adverse Pregnancy Outcomes and Cardiovascular Disease Risk: Unique Opportunities for Cardiovascular Disease Prevention in Women: A Scientific Statement From the American Heart Association
Circulation. 2021 Mar 29:CIR0000000000000961. doi: 10.1161/CIR.0000000000000961. Online ahead of print.ABSTRACTThis statement summarizes evidence that adverse pregnancy outcomes (APOs) such as hypertensive disorders of pregnancy, preterm delivery, gestational diabetes, small-for-gestational-age delivery, placental abruption, and pregnancy loss increase a woman's risk of developing cardiovascular disease (CVD) risk factors and of developing subsequent CVD (including fatal and nonfatal coronary heart disease, stroke, peripheral vascular disease, and heart failure). This statement highlights the importance of recognizing APOs...
Source: Circulation - March 29, 2021 Category: Cardiology Authors: Nisha I Parikh Juan M Gonzalez Cheryl A M Anderson Suzanne E Judd Kathryn M Rexrode Mark A Hlatky Erica P Gunderson Jennifer J Stuart Dhananjay Vaidya American Heart Association Council on Epidemiology and Prevention; Council on Arteriosclerosis, Thrombos Source Type: research

Study Selection for Reviewing Statins Effects on Low-Density Lipoprotein Cholesterol
To the Editor: We read with interest the systematic review and meta-analysis by Dr Byrne and colleagues. Although the authors conclude that “the absolute benefits of statins are modest,” we identified factors that weaken their argument. Pooling of studies with different clinical contexts may lead to erroneous conclusions. Accordingly, of the 21 randomized clinical trials included, only 6 were secondary prevention trials in which the effect of statins on prognosis was more potent. Furthermore, the specific limitations of the included studies cast doubt on the conclusions. The CORONA (Controlled Rosuvastatin Multinationa...
Source: JAMA Internal Medicine - June 27, 2022 Category: Internal Medicine Source Type: research

Effect of omega-3 fatty acids on cardiovascular events in high-risk patients with hypertriglyceridemia in Japan: a 3-year post-marketing surveillance study (OCEAN3 survey)
CONCLUSIONS: Among patients receiving statins, cardiovascular event incidence did not differ significantly between O3AEE-treated patients and non-O3AEE-treated patients. Further studies are required before definitive conclusions can be drawn on the effect of O3AEE on cardiovascular event incidence in high-risk patients with hypertriglyceridemia.TRIAL REGISTRATION: ClinicalTrials.gov, NCT02285166.PMID:35772177 | DOI:10.1080/14740338.2022.2094914
Source: Expert Opinion on Drug Safety - June 30, 2022 Category: Drugs & Pharmacology Authors: Tamio Teramoto Hisao Ogawa Hirotsugu Ueshima Yasushi Okada Kazuo Haze Shigeyuki Matsui Keita Fujikawa Takamasa Hashimoto Sho Sakui Kunihiko Nishimura Mika Kajita Atsushi Horimoto Jovelle Fernandez Source Type: research

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