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Self-reported snoring patterns predict stroke events in high-risk patients with obstructive sleep apnea: post-hoc analyses of the SAVE study.
Abstract BACKGROUND: The relation of snoring to risks of stroke and other major cardiovascular (CV) events is uncertain. RESEARCH QUESTION: We aimed to determine associations of snoring patterns and major CV events in relation to the obstructive sleep apnea (OSA), among participants of the international Sleep Apnea cardiovascular Endpoints (SAVE) trial. STUDY DESIGN: and Methods: Post-hoc analyses of the SAVE trial, which involved 2687 patients with co-existing moderate-severe OSA and established coronary or cerebral CV disease, who were randomly allocated to continuous positive airway pressure (CPAP) tr...
Source: Chest - July 13, 2020 Category: Respiratory Medicine Authors: Li J, McEvoy RD, Zheng D, Loffler KA, Wang X, Redline S, Woodman RJ, Anderson CS Tags: Chest Source Type: research

Impact of lung function on cardiovascular diseases and cardiovascular risk factors: a two sample bidirectional Mendelian randomisation study
Conclusion Higher lung function likely protect against CAD and stroke.
Source: Thorax - January 12, 2022 Category: Respiratory Medicine Authors: Au Yeung, S. L., Borges, M. C., Lawlor, D. A., Schooling, C. M. Tags: Thorax Respiratory epidemiology Source Type: research

Etiology, clinical characteristics, and outcome of infective endocarditis: 10-year experience from a tertiary care center in Pakistan
In conclusion, our study provided valuable data on the clinical characteristics and outcomes of patients with IE in a developing country. S. aureus was the most common causative agent. Heart failure and stroke were the most common complications. The presence of prosthetic valves, history of chronic kidney disease, ischemic heart disease and previous stroke were associated with a significantly increased risk of mortality. Surgical management was not associated with improved outcomes.PMID:35347974 | DOI:10.4081/monaldi.2022.2212
Source: Monaldi Archives for Chest Disease - March 29, 2022 Category: Respiratory Medicine Authors: Sara Salim Ali Imran Ahmed Qureshi Ahmed Ayaz Ainan Arshad Awais Farhad Bushra Jamil Muhammad Rizwan Sohail Source Type: research

Study on the predictive ability of emergency CHADS < sub > 2 < /sub > score and CHA < sub > 2 < /sub > DS < sub > 2 < /sub > -VASc score for coronary artery disease and prognosis in patients with acute ST-segment elevation myocardial infarction
CONCLUSIONS: Multiple factors jointly affect the severity and prognosis of CAD in patients with acute STEMI. The CHA2DS2-VASc score is better than the CHADS2 score in predicting the severity of coronary artery lesions and prognosis of patients, providing theoretical support for clinical practice.PMID:35928606 | PMC:PMC9344425 | DOI:10.21037/jtd-22-763
Source: Journal of Thoracic Disease - August 5, 2022 Category: Respiratory Medicine Authors: Xin Huang Hong Lv Zeyan Liu Yuan Liu Xue Yang Source Type: research

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