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New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Regular activity may help some people stay 'fat and fit'
Conclusion As people often say, if exercise was a medicine, it would be hailed as a miracle cure. This study suggests that what we already know about the benefits of exercise may extend to reducing risk of cardiovascular disease for middle aged and older people, even if they are overweight or obese. But the study has some limitations. This type of study can't prove that one factor – exercise – is responsible for the lower risk of heart attack and stroke among overweight or obese people who exercise more. It's possible that other factors are important – for example people's income may be linked to their opportuniti...
Source: NHS News Feed - March 2, 2017 Category: Consumer Health News Tags: Obesity Lifestyle/exercise Heart/lungs Source Type: news

Yoga may help protect against heart disease
ConclusionOverall, this review suggests that yoga may be beneficial in reducing risk factors for cardiovascular disease and metabolic syndrome.While these are encouraging findings, the authors also caution that these are based on trials with some limitations, including: There was a wide variation in the type of yoga practised, the frequency and the length of each session across the studies. This means it is difficult to say what the actual effects of each approach are, as the overall effects are just an average across all of these approaches. Some may have more of an effect and some may have less. The review does not rep...
Source: NHS News Feed - December 16, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Obesity Source Type: news

Offer weight loss surgery to obese people with diabetes
A quarter of the UK population is now obese, fuelling a rise in cases of type 2 diabetes, as well as heart disease, fatty liver disease and cancer. One in 20 people in the UK has type 2 diabetes, a progressive disease that causes heart disease, stroke, blindness, kidney failure and limb amputations. Updated NICE guidance focuses on identifying, assessing and treating people who are already obese.
Source: NHS Networks - December 1, 2014 Category: UK Health Authors: Maria Axford Source Type: news

NICE: 'Obese should be prescribed slimming clubs'
“GPs told to prescribe £100 slimming courses for millions of obese patients,” the Daily Mail reports. The news is based on new guidelines from the National Institute for Health and Care Excellence (NICE) that aim to encourage sustainable weight loss in the obese; “lose a little, and keep it off”. The guidance is mainly aimed at commissioners (who plan and agree which services will be provided in the NHS and monitor them), health professionals and groups who provide lifestyle weight management programmes. The recommendations may also be of interest to members of the public, including people who are overweight or o...
Source: NHS News Feed - May 28, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Food/diet Obesity QA articles Source Type: news

No pain, no gain? Getting the most out of exercise
Staying in shape has all sorts of benefits, from maintaining heart health to warding off dementia and cancerInactivity – fuelled by cars and a sedentary work life – has been dubbed the biggest public health problem of the 21st century, a global pandemic with dramatic impact on peoples wellbeing. The latest reports suggest that around the world it was responsible for 5.3 million deaths in 2008 – around one in 10 – more deaths than smoking.Not only does exercise make you fitter, it can also ward off numerous and often unexpected diseases, from heart attacks, to diabetes, some forms of cancer and dementia. There are t...
Source: Guardian Unlimited Science - January 13, 2014 Category: Science Authors: Catherine de Lange Tags: Cycling Fitness Sport Running Transport Yoga Weightlifting Features UK news Life and style Cycle hire schemes The Observer Swimming Science Source Type: news