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Systematic review of the relationship between Hollenhorst plaques and cerebrovascular events
CONCLUSION: The presence of asymptomatic retinal emboli indicates a risk of a cerebrovascular event when compared to patients with no plaques seen on fundoscopy. The evidence suggests that these patients warrant referral for medical optimization of cardiovascular risk factors. Currently, there is no recommendation to support carotid endarterectomy in patients with Hollenhorst plaques, or retinal emboli, and further studies are needed to assess this.PMID:36914563 | DOI:10.1177/17085381231163339
Source: Vascular - March 13, 2023 Category: Surgery Authors: Baker Moustafa Ghoneim Daniel Westby Mohamed Elsharkawi Marwa Said Stewart R Walsh Source Type: research

Central retinal artery occlusion: a retrospective study of disease presentation, treatment, and outcomes
CONCLUSIONS: The majority of patients with CRAO presented to eye care providers, and few present within the potential window for thrombolysis of 4.5 hours, highlighting the need for public awareness strategies. Our cohort highlights the significant rate of systemic comorbidity that exists in these patients.PMID:35307340 | DOI:10.1016/j.jcjo.2022.02.015
Source: Canadian Journal of Ophthalmology - March 21, 2022 Category: Opthalmology Authors: Meghan J Smith Matthew D Benson Matthew Tennant Imran Jivraj Source Type: research

Intraplaque CTA characteristics as predictors of symptomatology: a semiautomated volumetric analysis
ConclusionHigher volumes of intraplaque IPH, LRNC, matrix, and degree of arterial stenosis are associated with ipsilateral neurologic symptoms. Greater intraplaque proportions of LRNC are also associated with ipsilateral ischemic manifestations, suggesting that larger relative composition of lipids may be particularly predictive of symptomatology.
Source: Emergency Radiology - October 6, 2021 Category: Emergency Medicine Source Type: research

Predictive Factors for Pre-operative Recurrence of Cerebrovascular Symptoms in Symptomatic Carotid Stenosis.
CONCLUSION: More than every tenth patient with sCS experienced an early recurrent cerebrovascular event prior to scheduled CEA, despite optimal medication. However, stroke recurrence was lower than in earlier observational studies, which could be explained by improved care pathways, more aggressive medication, and expedited CEA. All recurrent strokes occurred in patients initially presenting with minor stroke. PMID: 33039297 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - October 7, 2020 Category: Surgery Authors: Eriksson H, Koskinen S, Nuotio K, Heikkilä HM, Vikatmaa P, Silvennoinen H, Valanne L, Mäyränpää MI, Kovanen PT, Soinne L, Lindsberg PJ, Ijäs P Tags: Eur J Vasc Endovasc Surg Source Type: research

Stenosis Length and Degree Interact With the Risk of Cerebrovascular Events Related to Internal Carotid Artery Stenosis
Conclusion: We found a statistically insignificant tendency for the ultrasound-measured length of sICAS<70% to be longer than that of sICAS≥70%. Moreover, the ultrasound-measured length of sICAS<90% was significantly longer than that of sICAS 90%. Among patients with sICAS≥70%, the degree and length of stenosis were inversely correlated. Larger studies are needed before a clinical implication can be drawn from these results. Introduction Internal carotid artery stenosis (ICAS) causes around one-fifth of ischemic cerebrovascular stroke and has the highest risk of early stroke recurrence...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research