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Estimation of mean population salt intakes using spot urine samples and associations with body mass index, hypertension, raised blood sugar and hypercholesterolemia: Findings from STEPS Survey 2019, Nepal
by Saroj Bhattarai, Bihungum Bista, Binod Kumar Yadav, Pradip Gynawali, Anil Poudyal, Anjani Kumar Jha, Meghnath Dhimal BackgroundHigh dietary salt intake is recognized as a risk factor for several non-communicable diseases (NCDs), in particular cardiovascular diseases (CVDs), including heart attack and stroke. Accurate measurement of population level salt intake is essential for setting targeted goals and plans for salt reduction strategies. We used a spot urine sample to estimate the mean population salt intake in Nepal and evaluated the association of salt intake with excess weight, hypertension, raised blood sugar and ...
Source: PLoS One - April 12, 2022 Category: Biomedical Science Authors: Saroj Bhattarai Source Type: research

Impact of salt intake reduction on CVD mortality in Costa Rica: A scenario modelling study
The objective of this study was to estimate the impact of reducing salt intake on CVD mortality in Costa Rica using a scenario simulation model. The Preventable Risk Integrated ModEl (PRIME) was used to estimate the number of deaths that would be averted or delayed in the Costa Rican population by following the national and the international guidelines to reduce salt consumption, according to two scenarios: A) 46% reduction and B) 15% reduction, both at an energy intake of 2171 kcal. The scenarios estimated that between 4% and 13%, respectively, of deaths due to CVD would be prevented or postponed. The hig hest percentages...
Source: PLoS One - January 12, 2021 Category: Biomedical Science Authors: Jaritza Vega-Solano Source Type: research

The incidence of recurrent cardiovascular events among acute coronary syndrome patients treated with generic or original clopidogrel in relation to their sociodemographic and clinical characteristics. The Aegean study.
Conclusions: The use of a generic clopidogrel besylate formulation was quite high in both urban and insular areas of Greece and had similar efficacy and safety profile with the original clopidogrel salt, supporting the routine use of this low-cost generic clopidogrel in the management of cardiovascular disease patients. PMID: 32863989 [PubMed]
Source: Archives of Medical Science - August 31, 2020 Category: Biomedical Science Tags: Arch Med Sci Source Type: research

Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease.
Conclusion: Salt exposure induced changes in gene and protein expression in an experimental model of SVD and its parent rat strain in multiple pathways involving components of the glio-vascular unit. Further studies in pertinent experimental models at different ages would help clarify the short and long-term effect of dietary salt in SVD.
Source: Clinical Science - April 9, 2018 Category: Biomedical Science Authors: Bailey, E. L., McBride, M. W., McClure, J. D., Beattie, W., Graham, D., Dominiczak, A. F., Smith, C., Wardlaw, J. M. Tags: PublishAheadOfPrint Source Type: research