Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease.

Conclusion: Salt exposure induced changes in gene and protein expression in an experimental model of SVD and its parent rat strain in multiple pathways involving components of the glio-vascular unit. Further studies in pertinent experimental models at different ages would help clarify the short and long-term effect of dietary salt in SVD.

Source: Clinical Science - April 9, 2018 Category: Biomedical Science Authors: Bailey, E. L., McBride, M. W., McClure, J. D., Beattie, W., Graham, D., Dominiczak, A. F., Smith, C., Wardlaw, J. M. Tags: PublishAheadOfPrint Source Type: research