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Total 42 results found since Jan 2013.

Acute bioenergetic intervention or pharmacological preconditioning protects neuron against ischemic injury.
In this study we have tested the concept of neuron protection by acute bioenergetic intervention or by pharmacological preconditioning with natural antioxidants. Adenosine triphosphate (ATP), pentobarbital, and suramin were encapsulated in pH-sensitive liposomes and used as bioenergy stabilizer. We induced ATP depletion model by incubating cells with media added with ATP-depleting agents for 2 hours. Treatment with bioenergy stabilizer started 10-min post inducing of ATP-depletion. The acute treatment with bioenergy stabilizer significantly increased cell viability in neuro-2a cells. In searching for a pharmacological prec...
Source: Journal of Experimental Stroke and Translational Medicine - December 2, 2015 Category: Neurology Tags: J Exp Stroke Transl Med Source Type: research

Eating chocolate may slightly lower your risk of stroke
ConclusionThis study used a large prospective cohort of English residents to estimate the risk chocolate poses to cardiovascular death and disease. In addition, they systematically combed the research literature for other similar studies, combining their results with that of other researchers. By comparing the highest chocolate consumers with chocolate abstainers, they found that chocolate was linked to a lower risk of stroke and cardiovascular disease. The risk for coronary heart disease was not statistically significant. Results from the meta-analysis of eight additional studies showed higher chocolate consumption was li...
Source: NHS News Feed - June 16, 2015 Category: Consumer Health News Tags: Food/diet Heart/lungs Neurology Source Type: news

Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease.
Authors: Román GC, Jackson RE, Gadhia R, Román AN, Reis J Abstract The mechanisms of action of the dietary components of the Mediterranean diet are reviewed in prevention of cardiovascular disease, stroke, age-associated cognitive decline and Alzheimer disease. A companion article provides a comprehensive review of extra-virgin olive oil. The benefits of consumption of long-chain ω-3 fatty acids are described. Fresh fish provides eicosapentaenoic acid while α-linolenic acid is found in canola and soybean oils, purslane and nuts. These ω-3 fatty acids interact metabolically with ω-6 fatty acids mainly linoleic...
Source: Revue Neurologique - September 16, 2019 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Ghana: World Stroke Day - Acting Fast to Cut Stroke in Half
[Ghanaian Times] Something interesting happened this morning. After my usual early morning posts about the health benefits of cocoa, a colleague reminded me that today, October 29, is World Stroke Day. The theme for this year's day is "Cut Stroke in Half" by 2030. The campaigns aims to reduce instances of stroke through an integrated prevention strategy.
Source: AllAfrica News: Health and Medicine - October 30, 2019 Category: African Health Source Type: news

Coffee, Tea, and Cocoa and Risk of Stroke Topical Review
Source: Stroke - December 23, 2013 Category: Neurology Authors: Larsson, S. C. Tags: Epidemiology Topical Review Source Type: research

Can chocolate make you smarter?
ConclusionStudies suggesting that chocolate is good for us always grab the headlines. However, as is so often the case, the reality is less clear than the headlines suggest.The current study adds to information about the links between diet and brain function – the way our brain processes and manages information. It found that people who scored better than average on these tests said they ate chocolate more often than people who scored worse than average on the tests. But we don't know why that is.There are quite a few limitations to the study. It's cross-sectional, which means we don't know which came first: the chocol...
Source: NHS News Feed - March 9, 2016 Category: Consumer Health News Tags: Food/diet Mental health Source Type: news

'Chocolate good for the heart' claims sadly too good to be true
Conclusion Health stories that suggest eating or drinking something we like, whether it's chocolate or wine, are always popular. But they don't really tell us anything we don't know already. Certain foods may have a small impact on certain types of diseases, but it's the overall diet that counts. Previous studies have already suggested that the antioxidant properties of cocoa could reduce the risk of cardiovascular disease, so it's surprising that this study focused on one particular cardiovascular disease, atrial fibrillation. AF is a common condition that affects heart rate, often causing a faster than normal, irregular ...
Source: NHS News Feed - May 24, 2017 Category: Consumer Health News Tags: Food/diet Heart/lungs Source Type: news

Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model
In this study, neuroprotective potential of theobromine (TBR) was evaluated in 2-vessel occlusion transient global cerebral ischemia-reperfusion (tGCI/R) rat model. Rats were treated with TBR (50, 100 mg/kg, p.o.) for 7 successive days, and subjected to bilateral common carotid artery occlusion (20 min) or sham surgery after last dose of TBR. Severe neurological deficits accompanied by brain infarction, blood-brain barrier abnormalities, and oedema were noted in rats subjected to tGCI/R, and these effects were prevented by TBR. TBR protected against lipid peroxidation and enhanced glutathione level in brain against tGCI/R....
Source: Cell Research - July 25, 2021 Category: Cytology Authors: Javeed Ahmad Bhat Sushma Gupta Manish Kumar Source Type: research

Effect of cocoa flavanol supplementation for prevention of cardiovascular disease events: The COSMOS randomized clinical trial
CONCLUSION: Cocoa extract supplementation did not significantly reduce total cardiovascular events among older adults but reduced CVD death by 27%. Potential reductions in total cardiovascular events were supported in per-protocol analyses. Additional research is warranted to clarify whether cocoa extract may reduce clinical cardiovascular events.PMID:35294962 | DOI:10.1093/ajcn/nqac055
Source: The American Journal of Clinical Nutrition - March 16, 2022 Category: Nutrition Authors: Howard D Sesso JoAnn E Manson Aaron K Aragaki Pamela M Rist Lisa G Johnson Georgina Friedenberg Trisha Copeland Allison Clar Samia Mora M Vinayaga Moorthy Ara Sarkissian William R Carrick Garnet L Anderson COSMOS Research Group Source Type: research