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Chocolate and risk of chronic disease: a systematic review and dose-response meta-analysis
ConclusionChocolate consumption is not related to risk for several chronic diseases, but could have a small inverse association with CHD and stroke. Our findings are limited by very low  or low credibility of evidence, highlighting important uncertainty for chocolate–disease associations.
Source: European Journal of Nutrition - February 25, 2019 Category: Nutrition Source Type: research

Total polyphenol intake, polyphenol subtypes and incidence of cardiovascular disease: The SUN cohort study
ConclusionThe intake of flavonoids showed an inverse association with risk of cardiovascular events in a prospective cohort of Spanish middle-aged adult university graduates.Registration number for clinical trialsNCT02669602 in Clinical Trials.
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

Chocolate intake and heart disease and stroke in the Women's Health Initiative: a prospective analysis
ConclusionWe observed no association between chocolate intake and risk of CHD, stroke, or both combined in participants free of pre-existing major chronic disease. The relation for both combined was modified by age, with a significant positive linear trend and an increased risk in the highest quintile of chocolate consumption among women age<65 y. This trial was registered at clinicaltrials.gov as NCT03453073.
Source: American Journal of Clinical Nutrition - June 21, 2018 Category: Nutrition Source Type: research

Chocolate intake and heart disease and stroke in the Women's Health Initiative: a prospective analysis.
Conclusion: We observed no association between chocolate intake and risk of CHD, stroke, or both combined in participants free of pre-existing major chronic disease. The relation for both combined was modified by age, with a significant positive linear trend and an increased risk in the highest quintile of chocolate consumption among women age <65 y. This trial was registered at clinicaltrials.gov as NCT03453073. PMID: 29931040 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - June 21, 2018 Category: Nutrition Authors: Greenberg JA, Manson JE, Neuhouser ML, Tinker L, Eaton C, Johnson KC, Shikany JM Tags: Am J Clin Nutr Source Type: research