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Role of the chemokine receptors CCR2 and CX3CR1 in an experimental model of thrombotic stroke.
This study underlines a key role of CCR2- and CX3CR1-expressing immune cells in the neuropathology associated with ischemic injuries. PMID: 29545116 [PubMed - as supplied by publisher]
Source: Brain, Behavior, and Immunity - March 12, 2018 Category: Neurology Authors: Cisbani G, Le Behot A, Plante MM, Préfontaine P, Lecordier M, Rivest S Tags: Brain Behav Immun Source Type: research

Effect of TTC Treatment on Immunohistochemical Quantification of Collagen IV in Rat Brains after Stroke
AbstractAlthough used extensively in stroke research, there is limited knowledge of how 2, 3, 5-triphenyltetrazolium chloride (TTC)-treated rat brain sections are altered and if they can be used for immunohistochemical quantification after staining with TTC. In the present study, we hypothesized that TTC treatment (TTC+) would not interfere with collagen IV immunohistochemical staining compared with non-TTC-treated (TTC −) brain slices. We further hypothesized that there would be no difference in autofluorescence or nonspecific secondary antibody fluorescence between TTC+ and TTC− brain slices. Coronal brain sections o...
Source: Translational Stroke Research - January 8, 2018 Category: Neurology Source Type: research

Effects of High- Versus Moderate-Intensity Training on Neuroplasticity and Functional Recovery After Focal Ischemia Basic Sciences
Conclusions—Low-volume HIT based on lactate threshold seems to be more effective after cerebral ischemia than work-matched MOD to improve aerobic fitness and grip strength and might promote cerebral plasticity.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Caroline Pin–Barre, Annabelle Constans, Jeanick Brisswalter, Christophe Pellegrino, Jerome Laurin Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

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