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Burdens on caregivers of patients with stroke during a pandemic: relationships with support satisfaction, psychological distress, and fear of COVID-19
Caregivers have faced unprecedented circumstances throughout the COVID-19 pandemic, but previous research only minimally addresses the caregivers' burden. Therefore, this study aimed to investigate the relatio...
Source: BMC Geriatrics - December 13, 2022 Category: Geriatrics Authors: Chieh-hsiu Liu, Yi-Jung Chen, Jung-Sheng Chen, Chia-Wei Fan, Meng-Tsang Hsieh, Chung-Ying Lin and Amir H. Pakpour Tags: Research Source Type: research

Immunoregulation of Ghrelin in neurocognitive sequelae associated with COVID-19: an in silico investigation
In this study, we explored, by bioinformatics approaches, the interaction between the multiple inflammatory agents involved in SARS-CoV-2 and Ghrelin (Ghre) together with its receptor GHSR-1A, which are described as anti-inflammatory mediators, in order to investigate what could trigger the hyper-inflammatory response in some SARS-CoV-2 patients. In our analysis, we found several interactions of Ghre and GHSR-1A with SARS-CoV-2 interacting human genes. We observed a correlation between Ghre, angiotensin-converting enzyme 2 ACE2, toll-like receptors 9 (TLR9), and Acidic chitinase (CHIA), whereas its receptor GHSR-1A interac...
Source: Gene - June 9, 2022 Category: Genetics & Stem Cells Authors: Cristina Russo Giovanna Morello Giuliana Mannino Antonella Russo Lucia Malaguarnera Source Type: research

Effects of statins on the risks of ischemic stroke and heart disease in human immunodeficiency virus infection, influenza and severe acute respiratory syndrome-associated coronavirus: respiratory virus infection with steroid use
CONCLUSION: Statin use was associated with lower aHRs for ischemic stroke and heart disease in those with HIS disorders with comorbidities.PMID:35590450 | DOI:10.1080/00325481.2022.2080359
Source: Postgraduate Medicine - May 20, 2022 Category: Internal Medicine Authors: Jun-Jun Yeh Meichu Lai Cheng-Li Lin Kuan-Hua Lu Chia-Hung Kao Source Type: research

IJERPH, Vol. 19, Pages 2278: The Impacts of COVID-19 on Healthcare Quality in Tertiary Medical Centers & mdash;A Retrospective Study on Data from Taiwan Clinical Performance Indicators System
IJERPH, Vol. 19, Pages 2278: The Impacts of COVID-19 on Healthcare Quality in Tertiary Medical Centers—A Retrospective Study on Data from Taiwan Clinical Performance Indicators System International Journal of Environmental Research and Public Health doi: 10.3390/ijerph19042278 Authors: Shih-An Liu Chieh-Liang Wu I-Ju Chou Pa-Chun Wang Chia-Ling Hsu Chia-Pei Chen To date, COVID-19 is by far the most impactful contagious disease of the 21st century and it has had a devastating effect on public health in countries around the globe. Elective medical services have declined markedly since the outbreak...
Source: International Journal of Environmental Research and Public Health - February 17, 2022 Category: Environmental Health Authors: Shih-An Liu Chieh-Liang Wu I-Ju Chou Pa-Chun Wang Chia-Ling Hsu Chia-Pei Chen Tags: Article Source Type: research

IJERPH, Vol. 19, Pages 162: Increased Anxiety and Depression Symptoms in Post-Acute Care Patients with Stroke during the COVID-19 Pandemic
This study aimed to explore the quality and stability of post-acute care for patients with stroke, including their functional outcomes, mental health and medical care in Taiwan during the COVID-19 pandemic. In this retrospective case–control study—based on propensity score matching—we assessed 11 patients admitted during the pandemic period (in 2021) and 11 patients admitted during the non-pandemic period (in 2020). Functional outcomes, including the scores of the modified Rankin Scale, Barthel Index, EuroQoL-5 Dimension, Lawton–Brody instrumental activities of daily ...
Source: International Journal of Environmental Research and Public Health - December 24, 2021 Category: Environmental Health Authors: Hsiang-Yun Chou Yu-Chun Lo Ya-Wen Tsai Chia-Li Shih Chieh-Ting Yeh Tags: Article Source Type: research

Cerebral venous thrombosis following COVID-19 vaccination
We appreciate the literature review by Abdalkader et al.1 to summarize the clinical epidemiology and features of cerebral venous thrombosis (CVT) in patients with coronavirus disease 2019 (COVID-19). Based on the meta-analysis performed by Baldini et al.,2 the estimated proportion of CVT cases among hospitalized patients with COVID-19 was 0.08%; therefore, it is not surprising that COVID-19 associated CVT had not been given much attention compared to the more common deep vein thrombosis and pulmonary embolism events in this patient population.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2021 Category: Neurology Authors: Chia Siang Kow, Syed Shahzad Hasan Tags: Letter to the Editor Source Type: research

Anticoagulant approach in COVID-19 patients with cerebral venous thrombosis
We appreciate Klein et al. [1] for reporting the case of cerebral venous thrombosis accompanied by hemorrhagic infarct in a young patient with novel coronavirus disease 2019 (COVID-19). The reporting of such a case would raise the awareness of the possibility of the occurrence of cerebral venous thrombosis in the course of COVID-19, especially among the young adults present with COVID-19 and neurological symptoms.
Source: Journal of Stroke and Cerebrovascular Diseases - August 2, 2020 Category: Neurology Authors: Chia Siang Kow, Abdullah Faiz Zaihan, Syed Shahzad Hasan Source Type: research