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Total 384 results found since Jan 2013.

Multiple cerebral infarction linked to underlying cancer: a review of Trousseau syndrome-related cerebral infarction
Br J Hosp Med (Lond). 2021 May 2;82(5):1-7. doi: 10.12968/hmed.2020.0696. Epub 2021 May 26.ABSTRACTTrousseau syndrome is a cancer-associated hypercoagulative state leading to venous or arterial thromboembolic events. Cerebral infarction is the most common result of arterial embolism and the pathogenesis is complicated, mainly associated with hypercoagulation and non-bacterial thrombotic endocarditis. On magnetic resonance imaging, multiple lesions are dispersed in more than two territories of the brain, often simultaneously involving the bilateral anterior and posterior circulation. Elevated plasma levels of D-dimer and fi...
Source: British Journal of Hospital Medicine - June 2, 2021 Category: Internal Medicine Authors: Chao Zhen Yabo Wang Haifeng Wang Dongmei Li Xin Wang Source Type: research

Cancer-Associated Atherothrombosis: The Challenge
Int J Angiol DOI: 10.1055/s-0041-1729920The association between venous thrombosis and malignancy, having typical features of a paraneoplastic syndrome, has been established for a century. Currently, it is recognized that arterial thromboembolism (ATE) may also behave as a paraneoplastic syndrome. Recent matched cohort studies, systematic reviews, and observational studies concur in showing an increased incidence of acute coronary events, ischemic stroke, accelerated peripheral arterial disease, and in-stent thrombosis during the 6-month period before cancer diagnosis, peaking for 30 days immediately before cancer diagnosis...
Source: International Journal of Angiology - July 19, 2021 Category: Cardiology Authors: Naschitz, Jochanan E. Tags: Review Article Source Type: research

Pulmonary Embolism
Pneumologie. 2021 Oct;75(10):800-818. doi: 10.1055/a-1029-9937. Epub 2021 Oct 18.ABSTRACTPulmonary embolism (PE) is a life-threatening disease and the third most frequent cardiovascular cause of death after stroke and myocardial infarction. The annual incidence is increasing (in Germany from 85 cases per 100000 population in the year 2005 to 109 cases per 100000 population in the year 2015). The individual risk for PE-related complications and death increases with the number of comorbidities and severity of right ventricular dysfunction. Using clinical, laboratory and imaging parameters, patients with PE can be stratified ...
Source: Pneumologie - October 18, 2021 Category: Respiratory Medicine Authors: Lukas Hobohm Mareike Lankeit Source Type: research

Bringing WISDOM to Breast Cancer Care
Dr. Laura Esserman answers the door of her bright yellow Victorian home in San Francisco’s Ashbury neighborhood with a phone at her ear. She’s wrapping up one of several meetings that day with her research team at University of California, San Francisco, where she heads the Carol Franc Buck Breast Care Center. She motions me in and reseats herself at a makeshift home office desk in her living room, sandwiched between a grand piano and set of enormous windows overlooking her front yard’s flower garden. It’s her remote base of operations when she’s not seeing patients or operating at the hospita...
Source: TIME: Health - October 22, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Source Type: news

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Work stress and loss of years lived without chronic disease: an 18-year follow-up of 1.5 million employees in Denmark
AbstractWe aimed to examine the association between exposure to work stress and chronic disease incidence and loss of chronic disease-free life years in the Danish workforce. The study population included 1,592,491 employees, aged 30 –59 in 2000 and without prevalent chronic diseases. We assessed work stress as the combination of job strain and effort-reward imbalance using job exposure matrices. We used Cox regressions to estimate risk of incident hospital-diagnoses or death of chronic diseases (i.e., type 2 diabetes, coronar y heart disease, stroke, cancer, asthma, chronic obstructive pulmonary disease, heart failure, ...
Source: European Journal of Epidemiology - March 21, 2022 Category: Epidemiology Source Type: research

Rapid MRI for ED stroke evaluation cuts costs, hospital length of stay
Using a rapid MRI protocol in the emergency department (ED) with people suspecte...Read more on AuntMinnie.comRelated Reading: Many significant imaging findings can be overlooked in ED patients Is neuroimaging overused for diagnosing dizziness? Short MRI comparable to CT for assessing interstitial lung disease Ultrashort brain MRI cost-effective compared to standard CT Short MRI exam shows promise for prostate cancer screening follow-up
Source: AuntMinnie.com Headlines - June 16, 2022 Category: Radiology Source Type: news

Late effects of childhood cancer recorded at a single outpatient clinic over the course of one year: implications for the follow-up care
Neoplasma. 2022 Jul 13:220531N584. doi: 10.4149/neo_2022_220531N584. Online ahead of print.ABSTRACTSystematic registration and analysis of detailed treatment data and data on late effects in survivors of childhood cancer are important both for building the evidence base for future assessment of current innovative therapies in pediatric oncology and for personalization of preventive care for survivors of childhood cancer. The paper provides a descriptive analysis of medical data (diagnosis, treatment, late effects, and health status) and selected patient-reported outcomes (mental health and psychosocial well-being) from a s...
Source: Neoplasma - July 12, 2022 Category: Cancer & Oncology Authors: Tomas Kepak Hana Hrstkova Vitezslav Dusek Marta Holikova Lucie Strublova Katerina Kepakova Source Type: research

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