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Very early infective endocarditis after transcatheter aortic valve replacement
ConclusionA significant proportion of IE episodes following TAVR occurs within a few weeks following the procedure and are associated with dismal outcomes. Some baseline and TAVR procedural factors were associated with VE-IE, andStaphylococcus aureus and enterococci were the main causative pathogens. These results may help to select the more appropriate antibiotic prophylaxis in TAVR procedures and guide the initial antibiotic therapy in those cases with a clinical suspicion of IE.Graphical abstractVery early infective endocarditis after trans-catheter aortic valve replacement. VE-IE indicates very early infective endocard...
Source: Clinical Research in Cardiology - March 9, 2022 Category: Cardiology Source Type: research

Implications of Methicillin-Resistant Staphylococcus aureus Carriage on Cardiac Surgical Outcomes.
CONCLUSIONS: MRSA carriers undergoing cardiac surgery are not at higher risk for mortality or SSI and can expect outcomes similar to those of non-carriers. Higher rates of postoperative MRSA infection and septicemia among carriers, although still very low, support the need for selective preoperative screening and prophylaxis when possible. PMID: 32387036 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - May 4, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Dewan KC, Dewan KS, Navale SM, Gordon SM, Svensson LG, Gillinov AM, Rich JB, Bakaeen F, Soltesz EG Tags: Ann Thorac Surg Source Type: research

Comparison Between Healthcare-Associated and Community-Acquired Infective Endocarditis at Tertiary Care Hospitals in Japan.
CONCLUSIONS: HAIE has different clinical characteristics and causative microorganisms, as well as worse prognosis, than CIE. Preventive strategies, and the prompt and appropriate identification of HAIE may improve the outcome of infective endocarditis. PMID: 32132310 [PubMed - as supplied by publisher]
Source: Circulation Journal - March 4, 2020 Category: Cardiology Authors: Kiriyama H, Daimon M, Nakanishi K, Kaneko H, Nakao T, Morimoto-Ichikawa R, Miyazaki S, Morita H, Daida H, Komuro I Tags: Circ J Source Type: research

“A contemporary description of staphylococcus aureus prosthetic valve endocarditis. Differences according to the time elapsed from surgery”
Staphylococcus aureus prosthetic valve endocarditis (SAPVE) has a poor prognosis. There are no large series that accurately describe this entity. This is a retrospective observational study on a prospective cohort from 3 Spanish reference hospitals for cardiac surgery, including 78 definitive episodes of left SAPVE between 1996 and 2016. Fifty percent had a Charlson Index score>5; 53% were health care-related. Twenty percent did not present fever. Complications at diagnosis included: severe heart failure (HF, 29%), septic shock (SS, 17.9%), central nervous system abnormalities (19%), septic metastasis (4%). Hemorrhagic s...
Source: Medicine - August 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Infective endocarditis requiring ICU admission: epidemiology and prognosis
Conclusions: Mortality in patients admitted to ICU for left-sided IE remains high, especially in cases of endocarditis due to methicillin resistant Staphylococcus aureus, when organ failures occur and ICU scores are high.
Source: Annals of Intensive Care - December 1, 2015 Category: Intensive Care Authors: Olivier LeroyHugues GeorgesPatrick DevosSteve BittonNathalie De SaCéline DedrieSébastien BeaguePierre DucqClaire Boulle-GeronimiDamien ThellierFabienne SaulnierSebastien Preau Source Type: research

Infectious Diseases: Images in Clinical Medicine
Editor: V. Dimov, M.D., Cleveland ClinicHypoglossal Nerve Palsy during Meningococcal Meningitis. NEJM, 10/2014.Herpes Zoster Involving the S1 Dermatome. NEJM, 05/2014.Tinea Faciei. NEJM, 05/2014.Disseminated Cryptococcosis in a CLL patient. 05/2014.Scrofuloderma due to Mycobacterium tuberculosis. NEJM, 06/2012.Leonine Facies in Lepromatous Leprosy. NEJM, 04/2012.Intestinal Infestation with Ancylostoma ceylanicum. NEJM, 03/2012.Kerion celsi form of tinea capitis caused by a T-cell hypersensitivity reaction. NEJM, 03/2012.Eye can see a nest of worms! Thelazia callipaeda. Lancet, 03/2012.Madura Foot. NEJM, 01/2012.Paragonimia...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Images Infectious Diseases Source Type: news