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Condition: Diabetes
Infectious Disease: Herpes

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Total 29 results found since Jan 2013.

Herpes Simplex Virus Meningoencephalitis Masquerading as Acute Stroke With Broca's Aphasia: A Case Report
This report highlights the importance of considering herpes encephalitis as a potential etiology in patients presenting with atypical neurological symptoms, even in the absence of typical radiological findings. Early diagnosis and appropriate management with acyclovir are crucial in improving outcomes in such cases.PMID:37476130 | PMC:PMC10354683 | DOI:10.7759/cureus.40618
Source: Herpes - July 21, 2023 Category: Infectious Diseases Authors: Gagandeep Singh Arora Don Phung Parneet Kaur Source Type: research

Antibodies to Human Herpesviruses and Rate of Incident Cardiovascular Events and All-Cause Mortality in the UK Biobank Infectious Disease Pilot Study
CONCLUSIONS: In this mostly White UK Biobank subset, neither HHV seropositivity nor titers were associated with stroke/MI or all-cause mortality.PMID:35873304 | PMC:PMC9301583 | DOI:10.1093/ofid/ofac294
Source: Herpes - July 25, 2022 Category: Infectious Diseases Authors: Petrina Chu Sharon Louise Cadogan Charlotte Warren-Gash Source Type: research

Pharmaceutical perspective of neuropathic pain management for primary care providers
Inflammopharmacology. 2022 Mar 28. doi: 10.1007/s10787-022-00963-7. Online ahead of print.ABSTRACTNeuropathic pain (NP) is a chronic condition that affects ~ 1% of the general population globally. Several conditions such as chronic diabetes, herpes zoster (HZ), cancer, HIV, stroke, multiple sclerosis, physical compression or damage of nerves and certain surgical procedures can lead to neuropathy and related pain. The condition is difficult to treat with traditional analgesic drugs. Typically, non-traditional analgesics are used in treating pain in this condition such as antidepressants and antiepileptic drugs. Opioids are ...
Source: Herpes - March 29, 2022 Category: Infectious Diseases Authors: Sandhya Jinesh Justin Kullgren Gollapudi S Shankar Rajan Radhakrishnan Source Type: research

Basis for diurnal exacerbation of neuropathic pain hypersensitivity and its application for drug development
J Biochem. 2021 Dec 30:mvab143. doi: 10.1093/jb/mvab143. Online ahead of print.ABSTRACTIn addition to diurnal rhythms in physiology and behavior, a variety of pathological conditions also exhibit marked day-night changes in symptom intensity, exemplified by allergic rhinitis, arthritis, asthma, myocardial infarction, congestive heart failure, stroke, and chronic pain disorders. Currently, novel therapeutic approaches are facilitated by the development of chemical compounds targeted to key proteins that cause diurnal exacerbation of pathological events. Neuropathic pain is a chronic condition that occurs by tumor-induced ne...
Source: Herpes - December 30, 2021 Category: Infectious Diseases Authors: Satoru Koyanagi Naoki Kusunose Sai Yasukochi Shigehiro Ohdo Source Type: research

The risk of laryngitis with herpes zoster infection: A nested case-control study using data from the Korean National Sample Cohort
CONCLUSIONS: HZI is independently associated with laryngitis. Results of this study have implications for etiological investigations and prevention strategies for laryngitis.PMID:34890416 | DOI:10.1371/journal.pone.0261366
Source: Herpes - December 10, 2021 Category: Infectious Diseases Authors: Young-Hoon Joo Hyun-Jin Lee Jun-Ook Park Young Joon Seo Tae Hoon Kong Kyoung Ho Park Source Type: research

Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications
AbstractPurpose of ReviewTranscutaneous electrical nerve stimulation (TENS) is widely used as a non-pharmacological approach for pain relief in a variety of clinical conditions. This manuscript aimed to review the basic mechanisms and clinical applications regarding the use of TENS for alleviating the peripheral (PNP) and central neuropathic pain (CNP).Recent FindingsBasic studies on animal models showed that TENS could alleviate pain by modulating neurotransmitters and receptors in the stimulation site and its upper levels, including the spinal cord, brainstem, and brain. Besides, many clinical studies have investigated t...
Source: Current Pain and Headache Reports - February 17, 2020 Category: Neurology Source Type: research

Disseminated cutaneous herpes zoster and multiple cerebral infarcts in an adult with diabetes mellitus
We present the case of a patient with a medical history of type 2 diabetes mellitus (DM) who experienced disseminated cutaneous VZV infection followed by multiple cerebral infarcts associated with VZV vasculopathy. Brain magnetic resonance imaging revealed multiple hyperintense lesions over the bilateral deep white matter and basal ganglia. A skin biopsy revealed small-vessel leukocytoclastic vasculitis with neutrophilic, lymphocytic, and eosinophilic infiltration. This case report describes the rare finding of cutaneous leukocytoclastic vasculitis in VZV infection and highlights that VZV infection is an uncommon but criti...
Source: Journal of NeuroVirology - January 14, 2020 Category: Neurology Source Type: research

Adult onset MELAS Syndrome Presenting as A Mimic of Herpes Simplex Encephalitis.
CONCLUSION: The clinical presentation and imaging studies of MELAS in adults are variable and may mimic those of HSE. Antiviral therapy should be administered until the diagnosis of MELAS is definitive. Infection and metformin may have also precipitated MELAS manifestation in this patient. Clinicians should avoid potential mitochondrial-toxic drugs in these patients. PMID: 31867706 [PubMed - in process]
Source: Acta Neurologica Taiwanica - December 25, 2019 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news