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Infectious Disease: COVID-19
Therapy: Stem Cell Therapy
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Total 23 results found since Jan 2013.
Treatments in Ischemic Stroke: Current and Future
Background and Aim: Despite progress made over the last 30 years, stroke is still a leading cause of disability and mortality; likewise, its burden is expected to increase over the next decades, due to population growth and aging. The development of drugs with better safety-efficacy profiles as well as strategies able to improve ischemic stroke management from the pre-hospital setting is needed.Summary: The pathophysiology of ischemic stroke involves multiple pathways resulting in cerebral artery obstruction and brain tissue ischemia. To date, the only approved drug for acute ischemic stroke is intravenous thrombolytic alt...
Source: European Neurology - August 2, 2022 Category: Neurology Source Type: research
COVID-19-Induced Stroke and the Potential of Using Mesenchymal Stem Cells-Derived Extracellular Vesicles in the Regulation of Neuroinflammation
In this study, we have first described the advantages and disadvantages of neuroinflammation in the pathological evolution after IS and summarized the characteristics of neuroinflammation in COVID-19-related stroke. Then, we have discussed the potential benefit of MSC-EVs in the regulation of inflammatory responses after COVID-19-induced ischemic events.PMID:35025001 | PMC:PMC8755896 | DOI:10.1007/s10571-021-01169-1
Source: Cellular and Molecular Neurobiology - January 13, 2022 Category: Cytology Authors: Leyla Norouzi-Barough Amir Asgari Khosroshahi Ali Gorji Fariba Zafari Mohammad Shahverdi Shahraki Sadegh Shirian Source Type: research
UCLA researchers study genetics ’ role in COVID-19 susceptibility, severity
“One of the most troubling things about COVID-19 is that we have a limited ability to predict how sick a specific individual will get,” said Dr. Daniel Geschwind.Geschwind is the MacDonald Distinguished Professor in Human Genetics at theDavid Geffen School of Medicine at UCLA and a member of theEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. And he ’s part of a team of UCLA scientists conducting research to learn why certain people get sick from the virus that causes COVID-19 — and why others don’t.Millions of people around the world have been infected with SARS-CoV-2, the v...
Source: UCLA Newsroom: Health Sciences - October 26, 2020 Category: Universities & Medical Training Source Type: news
Bioinformatics analysis of potential therapeutic targets for COVID-19 infection in patients with carotid atherosclerosis
CONCLUSIONS: With COVID-19 being a relatively new disease, associations have been proposed for its connections with several ailments and conditions, including IS and carotid atherosclerosis. More patient-based data-sets and studies are needed to fully explore and understand the relationship.PMID:35344771 | DOI:10.1016/j.jiph.2022.03.004
Source: Atherosclerosis - March 28, 2022 Category: Cardiology Authors: Liang Yanchao Zhang Sibin Ilgiz Gareev Xiang Huan Zhao Junfei Liu Chunyang Ozal Beylerli Albert Sufianov Yuan Chao Gai Yuyan Xu Xun Aamir Ahmad Liang Peng Yang Guang Source Type: research
Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 6, 2022 Category: Surgery Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research
