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How are Malformations of the Cerebral Cortex Grouped?
Discussion Cerebral cortex development is an extremely complex process overall. Our current understanding is incomplete and constantly changing as our understanding of genetics and the processes each gene controls emerges from scientific research. Neural cells are produced in the subventicular zone of the pallial or dorsal germinal epithelium. They then differentiate and migrate radially or tangentially to the cerebral cortex and organize themselves to function. Malformations of cortical development (MCD) is a heterogeneneous group of disorders that cause defective cortical development. These disorders are broadly catego...
Source: PediatricEducation.org - July 23, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

New spectrum of the neurologic consequences of Zika
Zika virus infection represents a new neuropathological agent with association to a wide spectrum of neurological complications: a) Congenital Zika Syndrome by affecting the neural stem cells of the human fetal brain; b) Guillain-Barr é Syndrome by an autoimmune response against peripheral myelin and/or axonal components or probable direct inflammatory reaction; c) Encephalitis/meningoencephalitis and myelitis by a direct viral inflammatory process on the central nervous system; d) Sensory neuropathy by infecting directly the pe ripheral neurons and causing substantial cell death and pathogenic transcriptional dysregulati...
Source: Journal of the Neurological Sciences - October 31, 2017 Category: Neurology Authors: Marco T. Medina, Marco Medina-Montoya Tags: Editorial Source Type: research