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Insomnia as an Independent Predictor of Incident Cardiovascular Disease in HIV: Data From the Veterans Aging Cohort Study
Background: Insomnia is associated with increased cardiovascular disease (CVD) risk in the general population and is highly prevalent in people with HIV. The CVD risk conferred by insomnia in the HIV population is unknown. Methods: Using the Veterans Aging Cohort Study Survey Cohort, insomnia symptoms were measured and dummy coded with the item, “Difficulty falling or staying asleep?” (5-point scale from no difficulty to bothers a lot). Incident CVD event ICD-9 codes (acute myocardial infarction, stroke, or coronary artery revascularization) were identified with the Department of Veterans Affairs (VA) and Medicare...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - April 9, 2019 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Hepatitis C virus coinfection independently increases the risk of cardiovascular disease in HIV‐positive patients
Summary Patients infected with HIV are at increased risk for cardiovascular disease despite successful antiretroviral therapy. Likewise, chronic hepatitis C virus (HCV) infection is associated with extrahepatic complications, including cardiovascular disease. However the risk of cardiovascular disease has not been formally examined in HIV/HCV‐coinfected patients. A retrospective study was carried out to assess the influence of HCV coinfection on the risk of cardiovascular events in a large cohort of HIV‐infected patients recruited since year 2004. A composite event of cardiovascular disease was used as an endpoint, inc...
Source: Journal of Viral Hepatitis - September 22, 2015 Category: Infectious Diseases Authors: J. V. Fernández‐Montero, P. Barreiro, C. Mendoza, P. Labarga, V. Soriano Tags: Original Article Source Type: research

Antivirals for HCV improve kidney and cardiovascular diseases in diabetic patients
(Wiley) Researchers from Taiwan reveal that antiviral therapy for hepatitis C virus (HCV) improves kidney and cardiovascular outcomes for patients with diabetes. Results of the study published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show that incidences of kidney disease, stroke, and heart attack were lower in patients treated with pegylated interferon and ribavirin compared to HCV patients not treated with antivirals or diabetic patients not infected with the virus.
Source: EurekAlert! - Infectious and Emerging Diseases - December 11, 2013 Category: Infectious Diseases Source Type: news